Results 71 to 80 of about 28,587 (260)
Therapeutic novelties of inhaled corticosteroids and bronchodilators in asthma
, 2015 Orally inhaled agents are a key therapeutic class for treatment of asthma. Inhaled corticosteroids (ICS) are the most effective anti-inflammatory treatment for asthma thus representing the first-line therapy and bronchodilators complement the effects of ...
P. Rogliani +7 more
core +1 more source
Allergy, EarlyView.ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin +4 more
wiley +1 more source
Variants in the interleukin 8 gene and the response to inhaled bronchodilators in cystic fibrosis
, 2017 Objective: Interleukin 8 protein promotes inflammatory responses, even in airways. The presence of interleukin 8 gene variants causes altered inflammatory responses and possibly varied responses to inhaled bronchodilators.
Dorotéia Rossi Silva Souza +5 more
core +2 more sources
, 2020 Increasing physical activity (PA) in patients with chronic obstructive pulmonary disease (COPD) is an important issue, however, the effect of bronchodilators on PA is still controversial.
Yoshiaki Minakata, Seigo Sasaki
core +1 more source
Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma
Allergy, EarlyView.EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler +22 more
wiley +1 more source
In Vitro Performance of Valved Holding Chambers in Paediatric Asthma Controller Therapy
Acta Paediatrica, EarlyView.ABSTRACT Aim Research on the drug delivery of inhaled corticosteroids and combination medications via valved holding chambers (VHCs) with children's breathing patterns is limited. We aimed to evaluate the in vitro performance of commercially available VHCs without facemasks under preschooler breathing conditions, focusing on total delivered dose and ...
Laura Ojanperä +2 more
wiley +1 more source
Use of breath-actuated inhalers in patients with chronic obstructive pulmonary disease
Медицинский совет, 2013 Chronic obstructive pulmonary disease is characterized by persistent progressive airflow limitation, and is associated with a chronic inflammatory response of the lungs to noxious particles or gases [1].
N. N. Mescheryakova
doaj +1 more source
Epidemiology and exogenous factors in nocturnal airflow limitation in children [PDF]
, 1996 The studies in this thesis add new insights to the concept on the pathophysiology of nocturnal airflow limitation in asthmatic children. Exogenous factors such as environmental tobacco smoke, the presence of pets, and high HDMA levels all independently ...
Rosman-Meijer, Geertruida Gerarda +1 more
core
Novel bronchodilators in the treatment of asthma and COPD
, 2013 This review analyses the patents published during the period January 1998 to August 2001 concerning bronchodilators, with special emphasis on their applications for the most important pulmonary diseases, which include asthma and COPD. Bronchodilators are
Campillo, Nuria E., Páez, Juan A.
core +1 more source