Results 91 to 100 of about 25,067 (232)

Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans

Experimental Physiology, EarlyView.
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts, Lydia L. Simpson, Jack S. Talbot, Elliott J. Jenkins, Travis D. Gibbons, Connor A. Howe, Lauren E. Maier, Emily R. Vanden Berg, Alex M. Williams, Philip N. Ainslie, Samuel J. Oliver, Craig D. Steinback, Mike Stembridge, Jonathan P. Moore   +13 more
wiley   +1 more source

Adjunctive Therapy With a Perna canaliculus and Euphausia superba Extract (EAB‐277TM) for Clinical Signs of Tracheal Collapse in Dogs: A Prospective, Randomized and Placebo‐Controlled Exploratory Trial

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Key findings: Adjunctive EAB‐277TM therapy may enhance airway health with the greatest improvements observed on Day 14 by improving exercise tolerance and reducing dynamic tracheal collapse. ABSTRACT Background Tracheal collapse is a common canine respiratory disease characterized by dorsoventral cartilage flattening, airway lumen narrowing and ...
Wasutorn Yangwanitset, Somkiat Huaijantug, Mookmanee Taechikantaphat, Melanie Hezzell, Walasinee Sakcamduang   +4 more
wiley   +1 more source

Risk Factors Associated with Misuse of Soft Mist Inhaler in Patients with Chronic Obstructive Pulmonary Disease

International Journal of COPD
Jong Geol Jang,* Young Seok Lee,* Kyung Soo Hong, June Hong Ahn Division of Pulmonology and Allergy, Department of Internal Medicine, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Republic of Korea*These ...
Jang JG, Lee YS, Hong KS, Ahn JH
doaj  

Effect of outpatient therapy with inhaled corticosteroids on decreasing in-hospital mortality from pneumonia in patients with COPD

International Journal of COPD, 2016
Yasuhiro Yamauchi,1 Hideo Yasunaga,2 Wakae Hasegawa,1 Yukiyo Sakamoto,1 Hideyuki Takeshima,1 Taisuke Jo,1,3 Hiroki Matsui,2 Kiyohide Fushimi,4 Takahide Nagase1 1Department of Respiratory Medicine, Graduate School of Medicine, 2Department of Clinical ...
Yamauchi Y, Yasunaga H, Hasegawa W, Sakamoto Y, Takeshima H, Jo T, Matsui H, Fushimi K, Nagase T   +8 more
doaj  

Agonist‐specific conformational dynamics at the β2‐adrenoceptor dictate allosteric modulation of Gαs signalling and bronchodilation

British Journal of Pharmacology, Volume 183, Issue 17, Page 5315-5335, September 2026.
Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah, Joshua Richard, Suvankar Ghosh, Jillian Jerwick, Joice T. Gavali, Raymond B. Penn, Alexander D. MacKerell Jr, Deepak A. Deshpande   +7 more
wiley   +1 more source

Field‐applicable low‐intensity exercise induces bronchodilation in horses with severe asthma

Equine Veterinary Journal, Volume 58, Issue 5, Page 1445-1453, September 2026.
Abstract Background Airway dysfunction in severe equine asthma (SEA) often results in early retirement or euthanasia of affected horses. Exercise‐induced bronchodilation occurs in horses with SEA after intense treadmill exercise, but the effects of a lighter, field‐applicable, training regimen remain largely unexplored.
Sophie Mainguy‐Seers, Sarah‐Maude Grondin, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Acute Exacerbation of Chronic Obstructive Pulmonary Disease Immediately After Extubation Following Percutaneous Nephrolithotomy: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT In patients with moderate‐to‐severe COPD, short‐term (1‐day) preoperative respiratory optimization may be insufficient to prevent acute exacerbation after extubation. Prolonged preoperative preparation, meticulous intraoperative lung‐protective ventilation, and a post‐extubation rapid‐response protocol are essential.
Mengyue Gu, Sen Yan, Ruiliang Wang, Fujun Zhang, Tianyao Zhang, Hui Zhong   +5 more
wiley   +1 more source

The burden of chronic obstructive pulmonary disease associated with maintenance monotherapy in the UK

International Journal of COPD, 2016
Susan C Edwards,1 Sian E Fairbrother,2 Anna Scowcroft,3 Gavin Chiu,4 Andrew Ternouth,3 Brian J Lipworth5 1Department of Market Access Pricing & Outcomes Research, 2Department of Medical Affairs - Respiratory, 3Department of Market Access ...
Edwards SC, Fairbrother SE, Scowcroft A, Chiu G, Ternouth A, Lipworth BJ   +5 more
doaj  

Improvement of Severe Volume Dependent Airway Closure With Tezepelumab: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Severe asthma may be complicated by airway remodeling, manifesting as higher symptom burden, airflow limitation and reduced treatment response. The effect of biologics on lung function changes remains uncertain. We report a 31‐year‐old man with severe uncontrolled asthma and chronic rhinosinusitis with nasal polyposis, characterized by ...
Philipp Suter, Robert Greig, Rory Chan, Brian J. Lipworth   +3 more
wiley   +1 more source

Efficacy and safety of tiotropium + olodaterol maintenance treatment in patients with COPD in the TONADO® and OTEMTO® studies: a subgroup analysis by age

International Journal of COPD, 2016
Gary T Ferguson,1 Jill P Karpel,2 Emmanuelle Clerisme-Beaty,3 Lars Grönke,4 Florian Voß,4 Roland Buhl5 1Pulmonary Research Institute of Southeast Michigan, Farmington Hills, MI, 2North Shore Medical Arts LLP, Great Neck, NY, 3Boehringer ...
Ferguson GT, Karpel JP, Clerisme-Beaty E, Grönke L, Voß F, Buhl R   +5 more
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