Results 91 to 100 of about 31,968 (274)

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

open access: yesRespirology, EarlyView.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota   +17 more
wiley   +1 more source

Allergic bronchopulmonary aspergillosis: diagnostic and treatment challenges [PDF]

open access: yes, 2016
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder, occurring mostly in asthmatic and cystic fibrosis patients, caused by an abnormal T-helper 2 lymphocyte response of the host to Aspergillus fumigatus antigens.
CINICOLA, BIANCA LAURA   +3 more
core   +1 more source

Dysphagia in Children With Autism Spectrum Disorder: A Scoping Review

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective There are four phases of swallowing: oral preparatory, oral transit, oropharyngeal, and esophageal. Disruption of any phase(s) can lead to dysphagia. Autism spectrum disorder (ASD) children have a high rate of dysphagia compared with neurotypical peers.
Chase Hintelmann   +3 more
wiley   +1 more source

Trends in bronchoscopic findings over a decade [PDF]

open access: yes, 2009
The incidence of lung cancer in Maltese males is higher than that in females. However trends in Maltese and other foreign populations indicate a substantial recent increment in the diagnosis of lung cancer in women.
Agius, Maria   +4 more
core  

Research Progress on Upper Airway Cough Syndrome

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Nasal Airway Transcriptome Reflects Selected Asthma‐Associated Gene Signatures in the Lower Airways

open access: yesAllergy, EarlyView.
Seven genes and two gene modules were consistently associated with asthma in both airway compartments in ARMS and were validated in ATLANTIS. The two modules reflected IL‐13 related inflammation and mast cell activity, respectively. Nasal gene signatures provide a non‐invasive proxy for selected bronchial asthma‐associated gene signatures. ARMS, Asthma
Hui Wen   +22 more
wiley   +1 more source

Malignant bronchial ulcer with coexistent pulmonary tuberculosis

open access: yesMonaldi Archives for Chest Disease, 2019
Ulceration in the bronchial mucosa is noted rarely in bronchoscopy. In the past, it was frequently encountered in endobronchial tuberculosis. Deep necrotic bronchial ulcers are seen very rarely in clinical practice.
Yuvarajan Sivagnaname   +2 more
doaj   +1 more source

Decentralised Clinical Guidelines Modelling with Lightweight Coordination Calculus

open access: yes, 2007
Background: Clinical protocols and guidelines have been considered as a major means to ensure that cost-effective services are provided at the point of care.
Dasmahapatra, Srinandan   +3 more
core  

Evolution of pulmonary inflammation and nutritional status in infants and young children with cystic fibrosis [PDF]

open access: yes, 2011
Introduction Improved nutrition is the major proven benefit of newborn screening programmes for cystic fibrosis (CF) and is associated with better clinical outcomes.
Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF)   +6 more
core   +1 more source

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