Results 41 to 50 of about 82,573 (267)

Temporal trends of tracheal, bronchus, and lung cancer between 2010 and 2019, in Asian countries by geographical region and sociodemographic index, comparison with global data

Thoracic Cancer, 2023
Background This study aimed to describe the trends in incidence, mortality, and burden of tracheal, bronchial and lung (TBL) cancer in Asia from 2010 through 2019 and compare with global and other continental data.
Fatemeh Rezaei, Afrooz Mazidimoradi, Ali Rayatinejad, Leila Allahqoli, Hamid Salehiniya   +4 more
doaj   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Bronchial tree of the human embryo: Categorization of the branching mode as monopodial and dipodial.

PLoS ONE, 2021
Some human organs are composed of bifurcated structures. Two simple branching modes-monopodial and dipodial-have been proposed. With monopodial branching, child branches extend from the sidewall of the parent branch.
Sena Fujii, Taiga Muranaka, Jun Matsubayashi, Shigehito Yamada, Akio Yoneyama, Tetsuya Takakuwa   +5 more
doaj   +1 more source

Whistle in the bronchus

Annals of Thoracic Medicine, 2007
An 18-year-old male presented with 4 weeks' history of productive cough and fever that had started 1 day after alleged ingestion of a plastic whistle. Multiple courses of antibiotics had proved ineffective. Crepitation and a localized wheeze on right chest were observed on clinical examination.
Koul Parvaiz, Wahid Abdul, Bhat Tariq, Hussain Tajamul   +3 more
openaire   +3 more sources

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Distinguishing bronchoscopically observed anatomical positions of airway under by convolutional neural network

Therapeutic Advances in Chronic Disease, 2023
Background: Artificial intelligence (AI) technology has been used for finding lesions via gastrointestinal endoscopy. However, there were few AI-associated studies that discuss bronchoscopy.
Chongxiang Chen, Felix JF Herth, Yingnan Zuo, Hongjia Li, Xinyuan Liang, Yaqing Chen, Jiangtao Ren, Wenhua Jian, Changhao Zhong, Shiyue Li   +9 more
doaj   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

Imaging features of rhinosporidiosis on contrast CT

Indian Journal of Radiology and Imaging, 2013
Context: Rhinosporidiosis is a chronic granulomatous disease endemic in certain regions of India. Computed tomography (CT) imaging appearances of rhinosporidiosis have not been previously described in the literature.
Shailesh M Prabhu, Aparna Irodi, Hannah L Khiangte, V Rupa, P Naina   +4 more
doaj   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

Endobronchial Myoepithelioma With Fluorodeoxyglucose Uptake

Respirology Case Reports
Myoepitheliomas of the respiratory organs are extremely rare. We report a case of endobronchial myoepithelioma in a 43‐year‐old woman presenting to hospital with a cough.
Taro Abe, Keitaro Nakamoto, Eriko Ieki, Miku Oda, Yoshifumi Hirata, Isao Kataoka, Kazuharu Suda, Aya Isomura, Junji Shibahara, Yutaka Suzuki   +9 more
doaj   +1 more source