Results 51 to 60 of about 82,573 (267)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

Hepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo, Ivana Nikolic, Alfonso Mora, Elena Rodríguez, Luis Leiva‐Vega, Aránzazu Pintor‐Chocano, Daniel Horrillo, Lourdes Hernández‐Cosido, Jorge L. Torres, Eva Novoa, Rubén Nogueiras, Gema Medina‐Gómez, Miguel Marcos, Magdalena Leiva, Guadalupe Sabio   +14 more
wiley   +1 more source

Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature review

Respirology Case Reports
Tracheo‐bronchial adenoid cystic carcinoma (TBACC) is a rare disease. Its treatment is mainly surgical. We herein describe the clinical and para‐clinical varieties of TBACC as well as their surgical treatment and prognosis.
Kaouther Ben Amara, Imen Bouassida, Rahma Ayadi, Mariem Affes, Amina Abdelkbir, Mahdi Abdennadher, Salma Ben Othmen, Ayda Ayadi‐Kaddour, Hazem Zribi, Adel Marghli   +9 more
doaj   +1 more source

Rare multiple bronchial abnormalities in a patient with congenital heart disease

Clinical Case Reports, 2017
Key Clinical Message Although many variations regarding lobar or segmental bronchial subdivisions have been described, abnormal bronchi originating from the trachea or main bronchi are relatively rare.
Andrew C. Chatzis, Joanne Sofianidou, Theofili Kousi, Olga Karapanagiotou, Meletios A. Kanakis   +4 more
doaj   +1 more source

Caveolin-1: Functional Insights into Its Role in Muscarine- and Serotonin-Induced Smooth Muscle Constriction in Murine Airways

Frontiers in Physiology, 2017
An increased bronchoconstrictor response is a hallmark in the progression of obstructive airway diseases. Acetylcholine and 5-hydroxytryptamine (5-HT, serotonin) are the major bronchoconstrictors.
Maryam Keshavarz, Heike Schwarz, Petra Hartmann, Silke Wiegand, Melanie Skill, Mike Althaus, Wolfgang Kummer, Wolfgang Kummer, Gabriela Krasteva-Christ, Gabriela Krasteva-Christ   +9 more
doaj   +1 more source

Investigation of the non‐small cell lung cancer patients with bronchus involvements: A population‐based study

The Clinical Respiratory Journal, 2023
Background We aimed to explore the prognostic differences among T1‐4N0‐2M0 non‐small cell lung cancer (NSCLC) patients with bronchus involvements and to validate the T category of these patients in an external cohort.
Gang Wang, Yong‐Qiang Ye, Bao‐Long Xie, Xiang‐Min Lai, Sheng‐Peng Zhong   +4 more
doaj   +1 more source

Monolayer MoS2 With Ultrahigh Piezoelectricity: From ALD Dose Control to Device Performance

Advanced Science, EarlyView.
This study demonstrates that controlling precursor dosages in atomic layer deposition (ALD) serves to regulate ultrathin oxide quality, which in turn determines sulfurization behavior and MoS2 monolayer continuity. The resulting continuous, low‐defect monolayers enable improved piezoelectric performance and support a flexible slippage sensor, linking ...
Yun Li, Ming Rui Joel Tan, Subhasis Das, Yafei Du, Wenjie Lai, Jiamin Amanda Ong, Yongli He, Yiming Zou, Anatoli Kurkin, Peiwen Huang, Jiajun Liu, Xingyu Chen, Alfred Iing Yoong Tok, Soo Jay Phee, Lioz Etgar, Shlomo Magdassi, Pooi See Lee   +16 more
wiley   +1 more source

18F‐FAPI versus 18F‐FDG PET/CT in the Diagnosis of Relapsing Polychondritis

Clinical Case Reports
Relapsing polychondritis (RP) is a rare immune‐mediated systemic inflammatory disease with diverse clinical manifestations. Independent involvement of the respiratory system in RP is uncommon. In the event of respiratory involvement as the initial airway‐
Xiaotong Guo, Juan Chen, Qian Zhao, Ying Liu, Xiuyan Wang   +4 more
doaj   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

The importance of patient positioning for bronchial foreign body extraction: a case report

Veterinární Medicína, 2009
A bronchial foreign body was found in a dog. A circular foreign body was found radiographically in the left bronchus right after the bifurcation. A lateral thoracotomy was performed at the fifth intercostal space, guided by fluoroscopy.
B. Pirkic, T. Babic, M. Stejskal, D. Maticic, D. Vnuk, M. Kreszinger, D. Stanin   +6 more
doaj   +1 more source