Results 171 to 180 of about 244,586 (299)

Rocks and clay: Potters' technological choices within the cultural dynamics of Bronze Age Kazakhstan. [PDF]

PLoS One
Doumani Dupuy PN, Amicone S, Frenken M, Berner J, Hermes T, Frachetti MD, Kiyasbek G.   +6 more
europepmc   +1 more source

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang, Jennifer A. Winton, Kyle T. Matschke, Alexandre Stouffs, Kimberly C. Lee, Yuanyuan Zhang, Wenlian Qiao, Weiwei Tan   +7 more
wiley   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Genomic insights from a final Bronze Age community buried in a collective tumulus in an Urnfield settlement in Northeastern Iberia. [PDF]

Commun Biol
Bretos Ezcurra M, Rohrlach AB, Papac L, Royo Guillén JI, Barquera R, Gómez Lecumberri F, Laborda Lorente R, Risch R, Krause J, Picazo Millán JV, Haak W, Villalba-Mouco V.   +11 more
europepmc   +1 more source

International student agency in academic self‐formation: Mobility as agency situated within knowledge structures

British Educational Research Journal, EarlyView.
Abstract With growing attention to student agency in academic and policy discourse, international education has become a prominent context for examining how students navigate new cultural, academic, linguistic and social environments. However, much of this discussion attributes student agency to the ‘international’ aspect, while overlooking the ...
Soyoung Lee
wiley   +1 more source

Cemento-Osseous Dysplasia in a Female Bronze Age Skeleton (North Caucasus). [PDF]

Head Neck Pathol
Gresky J, Frotscher M, Thiem S, Stoessel A, Kalmykov A, Berezina N.   +5 more
europepmc   +1 more source

A pipeline crisis or a sustainability crisis? Local and national succession planning for headteachers in England

British Educational Research Journal, EarlyView.
Abstract Recruiting and retaining school leaders is a challenge in many systems worldwide. Previous research has identified three distinct ways in which succession planning can be conceptualised and approached: a ‘pipeline’ approach seeks to match supply and demand for the posts that need filling; a ‘pool’ strategy involves proactively identifying and ...
Toby Greany, Pat Thomson, Tom Perry, Mike Collins   +3 more
wiley   +1 more source

Between soft power and suspicion: Chinese international students as diasporic actors in U.S.‐China geopolitical tensions

British Educational Research Journal, EarlyView.
Abstract This study examines the under‐theorized political role and identity of Chinese international students, who emerge as significant actors caught between U.S. soft power ambitions and rising geopolitical suspicion. Amid escalating U.S.‐China tensions, these students are forced to confront environments shaped by competing geopolitical discourses ...
Jing Yu
wiley   +1 more source

Diverse feasting networks at the end of the Bronze Age in Britain (c. 900-500 BCE) evidenced by multi-isotope analysis. [PDF]

iScience
Esposito C, Lamb AL, Andersen MB, Millet MA, Inglis E, Lugli F, Nederbragt AJ, Madgwick R.   +7 more
europepmc   +1 more source

“They say we're a rights‐respecting school but nobody knows what that really means”: Children's rights implementation in a Scottish secondary school

British Educational Research Journal, EarlyView.
Abstract Education has been an enduring feature of international human rights law since the Universal Declaration of Human Rights in 1948 and is the only human right that is compulsory for children. Appearing in all major human rights treaties, including the UN Convention on the Rights of the Child, education is multidimensional and a multiplier of ...
Amy Hanna
wiley   +1 more source