Results 131 to 140 of about 1,465,544 (217)
All‐D peptides that bind monomeric α‐synuclein shift the aggregation equilibrium, dismantle pathogenic fibrils, and suppress seeding activity in vitro and in cells. In a Parkinson's disease mouse model, treatment delays disease progression and extends survival, supporting direct aggregate disassembly as a disease‐modifying therapeutic strategy for ...
Sara Reithofer +17 more
wiley +1 more source
Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems
Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai +6 more
wiley +1 more source
The methanolic extract of Cinnamomum verum exhibited antibacterial and antibiofilm activities, enhanced the efficacy of conventional antibiotics against multidrug‐resistant bacteria, and showed favorable interactions with key bacterial targets in molecular docking analyses, supporting its potential as a natural antimicrobial adjuvant for combating ...
Hayet Edziri +11 more
wiley +1 more source
Natural compound phosphonothrixin's herbicidal activity resides exclusively in its (S)‐enantiomer, yet existing enantioselective syntheses are cumbersome, and direct chiral LC separation is hampered by the compound's high polarity, lack of aromatic groups, and metal chelation–induced peak tailing.
Mirna Maalouf +8 more
wiley +1 more source
Unveiling the chemical and biological properties of Litsea cubeba essential oil. ABSTRACT Litsea cubeba essential oil (LCEO) is recognised for its broad spectrum of biological activities, including antimicrobial and insecticidal effects, making it a promising natural alternative to synthetic agents.
Miroslava Kačániová +10 more
wiley +1 more source
A chitosan–gelatin edible coating containing nanoemulsions of Satureja bachtiarica and Nepeta binaludensis essential oils was developed and applied to burgers during refrigerated storage. The active coating improved microbial stability and helped maintain the physicochemical and sensory quality of burgers, demonstrating its potential for extending ...
Mahsa Nakhaei +4 more
wiley +1 more source
Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou +6 more
wiley +1 more source
Background: Application of natural compounds, including essential oils (EOs) and lysozyme is an effective method against growth of bacterial pathogens in foods.
T Mohajerfar +5 more
doaj
Abstract BACKGROUND Inhibitors of angiotensin‐converting enzyme (ACE) are used in pharmaceuticals and functional foods. Captopril, a well‐known ACE inhibitor, extends the lifespan of the nematode Caenorhabditis elegans. Bioactive peptides derived from food sources are considered safe ACE inhibitors.
Issei Yokoyama +6 more
wiley +1 more source
Thermotolerant Campylobacter spp., the leading cause of foodborne bacterial diarrhoea in Europe, are fastidious in vitro. Thus, a cultural detection can be challenging.
Buhler, Christiane +5 more
core

