Results 51 to 60 of about 31,984 (296)

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

open access: yesAdvanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang   +12 more
wiley   +1 more source

Brown algae [PDF]

open access: yesCurrent Biology, 2011
Cock, J. Mark   +2 more
openaire   +5 more sources

Mussel‐Bioinspired Edible Ca2+‐Crosslinked Alginate Hydrogel Electrodes for Glucose Gastrointestinal Monitoring

open access: yesAdvanced Science, EarlyView.
A fully edible soft electrode is engineered from Ca2⁺‐crosslinked alginate integrated with polydopamine, silver nanoparticles, and food‐grade glucose oxidase. The hybrid hydrogel combines ionic and electronic conduction, enabling efficient glucose‐to‐H2O2 conversion and catalytic reduction in simulated intestinal fluid.
Verdiana Marchianò   +10 more
wiley   +1 more source

Pigments Content (Chlorophylls, Fucoxanthin and Phycobiliproteins) of Different Commercial Dried Algae

open access: yesSeparations, 2020
Algae are a complex, polyphyletic group of organisms, affordable and naturally rich in nutrients, but also valuable sources of structurally diverse bioactive substances such as natural pigments.
Catarina Osório   +6 more
doaj   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu   +13 more
wiley   +1 more source

Comparative description of brown algae from the coastal zone of Far East

open access: yesИзвестия ТИНРО, 2015
Data on stock and distribution of commercial and prospective for harvesting brown algae at the coast of Russian Far East are presented and compared. Their total biomass in the traditional harvesting grounds prevails 3.5 million tons. Saccharina japonica,
Natalia M. Aminina
doaj   +1 more source

Antidiabetic Potential of Marine Brown Algae—a Mini Review

open access: yesJournal of Diabetes Research, 2020
Marine algae are an important source of bioactive metabolites in drug development and nutraceuticals. Diabetes mellitus is a metabolic disorder and the third leading cause of death worldwide due to lifestyle changes associated with rapid urbanization ...
Thilina L. Gunathilaka   +3 more
doaj   +1 more source

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

open access: yesAdvanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács   +9 more
wiley   +1 more source

3D Hydrogel Cell Cultures and Their Biomedical Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai   +7 more
wiley   +1 more source

Identification, characterization and expression analysis of the CDPK family in kelp Saccharina japonica

open access: yesBMC Genomics
Background Calcium-dependent protein kinases (CDPKs) are crucial sensors and serine/threonine protein kinases in plants, involved in growth, development, and stress responses.
Minghui Sun   +4 more
doaj   +1 more source

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