Results 51 to 60 of about 48,024 (205)

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Epigenetic Clock in Bears: A Simple Cost‐Effective Blood DNA Methylation‐Based Age Estimation Method Applicable to Multiple Bear Species

Ecology and Evolution
Age is an essential factor to understand the life history and demographic parameters of wildlife. Previously, we established an age estimation method for brown bears based on blood DNA methylation level.
Michito Shimozuru, Shiori Nakamura, Jumpei Yamazaki, Yojiro Yanagawa, Hiroo Tamatani, Misako Kuroe, Koji Yamazaki, Shinsuke Koike, Yusuke Goto, Tomoko Naganuma, Kahoko Tochigi, Akino Inagaki, Naoki Takekoshi, Seungyun Baek, Nobutaka Sato, Yusuke Honda, Toshio Tsubota, Hideyuki Ito   +17 more
doaj   +1 more source

A dispersing bear in Białowieża Forest raises important ecological and conservation management questions for the central European lowlands

Global Ecology and Conservation, 2020
In Europe brown bears are currently largely confined to mountainous areas and eastern European refugia with sparse human populations. Poland typifies this distribution, with bears being present in the Carpathian Mountains, but absent from the lowlands ...
T.A. Diserens, M. Churski, J.W. Bubnicki, K. Stępniak, A. Pekach, N. Selva, D.P.J. Kuijper   +6 more
doaj   +1 more source

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

Advanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini, Margalida Campaner Socias, Andreas Dimopoulos, Lorenza Rinvenuto, Enrico Pozzo, Diana Stalkopf, Angelo Serafini, Sara Morri, Ashley Wang, Rita La Rovere, Yoke Chin Chai, Sveva Bollini, Geert Bultynck, H. Llewelyn Roderick, Ioannis Papantoniou, Maurilio Sampaolesi   +15 more
wiley   +1 more source

Ancestral polymorphisms and sex-biased migration shaped the demographic history of brown bears and polar bears.

PLoS ONE, 2013
Recent studies have reported discordant gene trees in the evolution of brown bears and polar bears. Genealogical histories are different among independent nuclear loci and between biparentally inherited autosomal DNA (aDNA) and matrilineal mitochondrial ...
Shigeki Nakagome, Shuhei Mano, Masami Hasegawa   +2 more
doaj   +1 more source

Paths for colonization or exodus? New insights from the brown bear (Ursus arctos) population of the Cantabrian Mountains.

PLoS ONE, 2020
Over the centuries, the geographical distribution of brown bear (Ursus arctos) across the Iberian Peninsula has been decreasing, with the species currently confined to North Iberia.
Inês Gregório, Tânia Barros, Doriana Pando, Joaquín Morante, Carlos Fonseca, Eduardo Ferreira   +5 more
doaj   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

Advanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij, Antonia G. Vasilopoulou, Lennard Spauwen, Antoinette van den Dikkenberg, Jasmijn V. Korpershoek, Mylene de Ruijter, Jos Malda, Bas G. P. van Ravensteijn, Tina Vermonden   +8 more
wiley   +1 more source

Behavioral and Physiological Responses of Scandinavian Brown Bears (Ursus arctos) to Dog Hunts and Human Encounters

Frontiers in Ecology and Evolution, 2019
Innovations in biologging have offered new possibilities to better understand animals in their natural environment. Biologgers can be used by researchers to measure the impact of human disturbances on wildlife and guide conservation decisions.
Luc Le Grand, Neri H. Thorsen, Boris Fuchs, Alina L. Evans, Timothy G. Laske, Jon M. Arnemo, Jon M. Arnemo, Solve Sæbø, Ole-Gunnar Støen, Ole-Gunnar Støen   +9 more
doaj   +1 more source

Water Permeates and Plasticizes Amorphous Carbon Dots: Unraveling the Inner Accessibility of the Nanoparticles by Glass Transition Studies

Advanced Materials, EarlyView.
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti, Valerio Di Lisio, Lucia Cardo, Alessandro Camilli, Estela Moretón Alfonsín, Daniele Cangialosi, Amaia Iturrospe Ibarra, Arantxa Arbe, Maurizio Prato   +8 more
wiley   +1 more source