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Highlights in the knowledge of brown spider toxins [PDF]

open access: goldJournal of Venomous Animals and Toxins including Tropical Diseases, 2017
Brown spiders are venomous arthropods that use their venom for predation and defense. In humans, bites of these animals provoke injuries including dermonecrosis with gravitational spread of lesions, hematological abnormalities and impaired renal function.
Daniele Chaves-Moreira   +5 more
doaj   +4 more sources

Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates [PDF]

open access: yesToxins, 2023
Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade ...
Daniele Chaves-Moreira   +9 more
doaj   +2 more sources

Brown Spider (Loxosceles) Venom Toxins as Potential Biotools for the Development of Novel Therapeutics [PDF]

open access: yesToxins, 2019
Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological disturbances. Several toxins make
Daniele Chaves-Moreira   +11 more
doaj   +2 more sources

Hold the Chemo! Leukostasis, a Presentation of Brown Recluse Spider Bite: A Case Report [PDF]

open access: goldJournal of Investigative Medicine High Impact Case Reports, 2021
Brown recluse spiders, also known as Loxosceles reclusa, are endemic to the Southwest and Central Midwestern United States. A bite from this spider can cause a range of clinical manifestations, anywhere from a painless papular lesion to life-threatening ...
Ahmad Hallak MD   +5 more
doaj   +2 more sources

Partial proteomic analysis of brown widow spider (Latrodectus geometricus) venom to determine the biological activities

open access: goldToxicon: X, 2020
Spiders use their venom for defence and to capture prey. These venoms contain a cocktail of biologically active compounds that display several different biological activities, such as large molecules and small molecules including peptides, proteins ...
Pornsawan Khamtorn   +6 more
doaj   +2 more sources

Forty Years of the Description of Brown Spider Venom Phospholipases-D [PDF]

open access: yesToxins, 2020
Spiders of the genus Loxosceles, popularly known as Brown spiders, are considered a serious public health issue, especially in regions of hot or temperate climates, such as parts of North and South America.
Luiza Helena Gremski   +9 more
doaj   +2 more sources

Management of skin necrosis and wound dehiscence following brown recluse spider bite in the course of breast reconstruction: A case report [PDF]

open access: goldJPRAS Open
Background: Breast reconstruction following mastectomy is a critical component of breast cancer treatment, aimed at improving patient quality of life.
Sten Kajitani   +4 more
doaj   +2 more sources

TCTP from Loxosceles Intermedia (Brown Spider) Venom Contributes to the Allergic and Inflammatory Response of Cutaneous Loxoscelism [PDF]

open access: yesCells, 2019
LiTCTP is a toxin from the Translationally Controlled Tumor Protein (TCTP) family identified in Loxosceles brown spider venoms. These proteins are known as histamine-releasing factors (HRF). TCTPs participate in allergic and anaphylactic reactions, which
Marianna Boia-Ferreira   +12 more
doaj   +2 more sources

Clinical Spectrum of Hemolytic Anemia in Loxoscelism: Report of Two Cases Highlighting Variable Severity and Management [PDF]

open access: yesCase Reports in Hematology
Loxoscelism can cause local as well as systemic manifestations. Hematologic complications of brown recluse spider venom can be life-threatening.
Anas Al-Sadi   +4 more
doaj   +2 more sources

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