Results 111 to 120 of about 534,808 (344)

Use of bone-SPECT/CT and Na[18F]F-PET/CT in hyperparathyroidism

Frontiers in Nuclear Medicine
Hyperparathyroidism disrupts the balance of physiological bone formation and resorption by upregulating osteoclast activity. This leads to hypercalcemia, resulting in osteoporosis and eventually the formation of “brown tumors.” Currently used ...
Wouter van der Bruggen, Bernard F. Bulten   +1 more
doaj   +1 more source

Brown Tumour in a Patient with Secondary Hyperparathyroidism Resistant to Medical Therapy: Case Report on Successful Treatment after Subtotal Parathyroidectomy

International Journal of Endocrinology, 2009
Brown tumour represents a serious complication of hyperparathyroidism. Differential diagnosis, based on histological examination, is only presumptive and clinical, radiological and laboratory data are necessary for definitive diagnosis. Here we describe
Nicola Di Daniele, Stefano Condò, Michele Ferrannini, Marta Bertoli, Valentina Rovella, Laura Di Renzo, Antonino De Lorenzo   +6 more
doaj   +1 more source

Brown tumor in a patient with ectopic mediastinal parathyroid adenoma: A case report

Saudi Dental Journal, 2014
Brown tumors are uncommon focal giant-cell lesions that arise as a direct result of the effect of parathyroid hormone on bone tissue in some patients that have hyperparathyroidism.
Faiza A. Qari
doaj   +1 more source

Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]

, 2019
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence, Keenan, Bridget P, Kelley, Robin K   +2 more
core   +2 more sources

Multiple brown tumors within the cranium, in a patient with primary hyperparathyroidism. A case report and review of the literature

, 2022
Anas Bardeesi, Ashwag Alqurashi, Sumaih Shinawi, Firas R. Abi Sheffah, Abdulrazag Ajlan, Mohammad Binmahfoodh   +5 more
openalex   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

A 60-year-old man with chronic renal failure and a costal mass: a case report and review of the literature

Journal of Medical Case Reports, 2009
Introduction Brown tumors are a rare focal manifestation of osteitis fibrosa cystica, which results from hyperparathyroidism. Chronic kidney failure may lead to secondary or tertiary hyperparathyroidism and thus to osteitis fibrosa cystica and brown ...
Campuzano-Zuluaga Germán, Velasco-Pérez William, Marín-Zuluaga Juan Ignacio   +2 more
doaj   +1 more source

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

Hydrogel and scalp/skin conductivities impact dose from tumor treating fields

Frontiers in Bioengineering and Biotechnology
PurposeTumor Treating Fields (TTFields) are delivered by transducer arrays applied to scalp or body surface for treatment of multiple malignancies. Dermatologic complications are thought to be related to hydrogel situated between the electrodes and scalp
Edwin Lok, Edwin Lok, Olivia Liang, Olivia Liang, Monika Haack, Eric T. Wong, Eric T. Wong, Eric T. Wong   +7 more
doaj   +1 more source