Results 291 to 300 of about 4,305,734 (370)

Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential

open access: yesChemBioEng Reviews, EarlyView.
This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona   +2 more
wiley   +1 more source

Comparative Study of Platinum(II) and Platinum(IV) Complexes with 2‐(Pyridin‐2‐ylmethylamino)acetic Acid and 4‐(Pyridin‐2‐ylmethylamino)benzoic Acid: Experimental and Theoretical Analysis

open access: yesChemistryEurope, EarlyView.
GA: Ligand precursor 2‐(2‐pyridin‐2‐ylmethylamino)acetic acid (HL1) featuring flexible alkyl chains formed PtII and PtIV complexes with coordination involving the COO‐ group. In contrast, 4‐(2‐pyridin‐2‐ylmethylamino)benzoic acid (HL2) with a rigid p‐phenylene moiety successfully formed the desired PtII and PtIV complexes featuring free carboxylic acid
Stefan Richter   +4 more
wiley   +1 more source

Whole‐genome CRISPR‐Cas9 knockout screens identify SHOC2 as a genetic dependency in NRAS‐mutant melanoma

open access: yes
Cancer Communications, EarlyView.
Andrea Y. Gu   +6 more
wiley   +1 more source

Unjamming Transition as a Paradigm for Biomechanical Control of Cancer Metastasis

open access: yesCytoskeleton, EarlyView.
ABSTRACT Tumor metastasis is a complex phenomenon that poses significant challenges to current cancer therapeutics. While the biochemical signaling involved in promoting motile phenotypes is well understood, the role of biomechanical interactions has recently begun to be incorporated into models of tumor cell migration.
Grace Cai   +2 more
wiley   +1 more source

Comprehensive DSRCT multi‐omics analyses unveil CACNA2D2 as a diagnostic hallmark and super‐enhancer‐driven EWSR1::WT1 signature gene

open access: yes
Cancer Communications, EarlyView.
Florian Henning Geyer   +33 more
wiley   +1 more source

PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential

open access: yesCytoskeleton, EarlyView.
ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah   +2 more
wiley   +1 more source

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