Results 101 to 110 of about 62,050 (302)

Brucella abortus Traverses Brain Microvascular Endothelial Cells Using Infected Monocytes as a Trojan Horse

Frontiers in Cellular and Infection Microbiology, 2018
Neurobrucellosis is an inflammatory disease caused by the invasion of Brucella spp. to the central nervous system (CNS). The pathogenesis of the disease is not well characterized; however, for Brucella to gain access to the brain parenchyma, traversing ...
M. C. Miraglia, Ana M. Rodríguez, P. Barrionuevo, Julia Rodríguez, Kwang Sik Kim, Vida A. Dennis, M. Delpino, G. Giambartolomei   +7 more
semanticscholar   +1 more source

Diagnostic Performance of Four Serological Assays for Bovine Brucellosis and Optimised Cutoff Thresholds in an Endemic Region of Iran

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
A Venn diagram representing the overlaps and unique sets between four common serological tests used for Brucellosis detection: I‐ELISA, RBT, Wright and 2‐ME. Each circle corresponds to one of the tests, with varying levels of overlap indicating the number of positives shared between these tests.
Faranak Abnaroodheleh, Fereshteh Ansari, Youcef Shahali, Maryam Dadar   +3 more
wiley   +1 more source

Serological, cultural, and molecular evidence of Brucella infection in small ruminants in Pakistan

Journal of Infection in Developing Countries, 2015
Introduction: The objectives of the present study were to determine the seroprevalence and identify the causative agent of brucellosis in small ruminants in Pakistan.
Shahzad Ali, Shamim Akhter, Heinrich Neubauer, Falk Melzer, Iahtasham Khan, Qurban Ali, Muhammad Irfan   +6 more
doaj   +1 more source

Small ubiquitin-related modifier 2 affects the intracellular survival of 2308 by regulating activation of the NF-κB pathway

Innate Immunity, 2021
Brucella is a genus of Gram-negative intracellular pathogens that cause animal and human diseases. Brucella survival and replication inside immune cells is critical for the establishment of chronic infections.
Yueli Wang, Jing Xi, Peng Wu, Huan Zhang, Xiaoyu Deng, Yong Wang, Zhongchen Ma, Jihai Yi, Chuangfu Chen   +8 more
doaj   +1 more source

Persistence of Brucella abortus in the Bone Marrow of Infected Mice

Journal of Immunological Research, 2018
Brucellosis is a zoonotic bacterial infection that may persist for long periods causing relapses in antibiotic-treated patients. The ability of Brucella to develop chronic infections is linked to their capacity to invade and replicate within the ...
Cristina Gutiérrez-Jiménez, Lisiena Hysenaj, A. Alfaro-Alarcón, Ricardo Mora-Cartin, Vilma Arce-Gorvel, E. Moreno, J. Gorvel, E. Barquero-Calvo   +7 more
semanticscholar   +1 more source

A BtpB‐Deleted Brucella Vaccine Strain Provides Dual Advantages: Enhanced Protection and Diagnostic Differentiation Capability in Mice

Microbial Biotechnology, Volume 18, Issue 9, September 2025.
The Brucella A19ΔBtpB strain induces robust cellular immunity, reduces organ damage, protects mice against M28 infection and enables serological differentiation from other Brucella strains via iELISA. ABSTRACT The Brucella abortus A19 attenuated live vaccine poses potential infection risks during practical applications and interferes with serological ...
Zhenyu Xu, Xiaoyu Deng, Hengyun Gao, Yueli Wang, Huan Zhang, Yimei Xu, Haibo He, Aodi Wu, Yuchen Zhang, Jihai Yi, Zhen Wang, Chuangfu Chen, Zhongchen Ma   +12 more
wiley   +1 more source

Risk factors for human brucellosis in northern Tanzania [PDF]

, 2018
Little is known about the epidemiology of human brucellosis in sub-Saharan Africa. This hampers prevention and control efforts at the individual and population levels. To evaluate risk factors for brucellosis in northern Tanzania, we conducted a study of
Biggs, Holly M., Cash-Goldwasser, Shama, Cleaveland, Sarah, Crump, John A., Halliday, Jo E.B., Kazwala, Rudovick R., Lwezaula, Bingileki F., Maro, Venance P., Maze, Michael J., Mmbaga, Blandina T., Muiruri, Charles, Rubach, Matthew P., Saganda, Wilbrod, Shand, Michael C., Sharples, Katrina J., Stoddard, Robyn A.   +15 more
core   +1 more source

Characterization of Three Small Proteins in Brucella abortus Linked to Fucose Utilization

Journal of Bacteriology, 2018
Despite being one of the most common zoonoses worldwide, there is currently no human vaccine to combat brucellosis. Therefore, a better understanding of the pathogenesis and biology of Brucella spp., the causative agent of brucellosis, is essential for ...
James A. Budnick, Lauren M Sheehan, L. Kang, P. Michalak, Clayton C. Caswell   +4 more
semanticscholar   +1 more source

An HWE‐Family Histidine Kinase Modulates Brucella Cell Envelope Properties and Host Innate Immune Response

Molecular Microbiology, Volume 124, Issue 3, Page 245-258, September 2025.
The HWE‐family histidine kinase PhyK regulates the cell envelope structure of the intracellular pathogen Brucella ovis and affects how the host immune system responds to this bacterium. Deletion of phyK alters bacterial survival in the face of detergent stress and reduces immune activation in infected macrophages.
Xingru Chen, Emily Perez, Eleanor C. Scheeres, Rosemary Northcote, Aretha Fiebig, Andrew J. Olive, Sean Crosson   +6 more
wiley   +1 more source

Brucella abortus activates human neutrophils

Microbes and Infection, 2009
Human brucellosis is caused by infection with certain species of the genus Brucella and is characterized by bacterial persistence and inflammation of many host tissues. Neutrophils are one of the predominant cell types present in the infiltrate of these inflamed tissues, and due to their potential effect on the inflammatory response and tissue damage ...
Zwerdling, Astrid, Delpino, María Victoria, Pasquevich, Karina Alejandra, Barrionuevo, Paula, Cassataro, Juliana, Garcia Samartino, Clara, Giambartolomei, Guillermo Hernan   +6 more
openaire   +4 more sources