Results 121 to 130 of about 61,242 (304)

The Cellular Immunoprotection of BALB/C mice vaccinated with Salt-Extractable Brucella abortus S19 antigens and Immunoadjuvant βeta-glucan challenged with Brucella abortus Virulent Strain

The Iraqi Journal of Veterinary Medicine, 2015
The aim of this study was to evaluate the cellular immune responses of salt-Extractable Brucella abortus S19 antigens with immunoadjuvant soluble βeta-glucan in BALB/C mice later challenged with B. abortus virulent strain.
Nidhal Raoof Mahdi
doaj   +1 more source

TLR7 and TLR3 Sense Brucella abortus RNA to Induce Proinflammatory Cytokine Production but They Are Dispensable for Host Control of Infection

Frontiers in Immunology, 2017
Brucella abortus is a Gram-negative, facultative intracellular bacterium that causes brucellosis, a worldwide zoonotic disease leading to undulant fever in humans and abortion in cattle.
Priscila C. Campos, M. T. Gomes, Erika S. Guimarães, G. Guimarães, S. Oliveira   +4 more
semanticscholar   +1 more source

The Induction and Characterization of a Potential Rough‐Type Brucella Vaccine Candidate Strain RA343, and Its Safety, Protective Efficacy in Mouse and Guinea Pig Models

Animal Research and One Health, Volume 3, Issue 2, Page 195-205, May 2025.
Brucellosis is a zoonotic disease caused by Brucella spp. which seriously jeopardize the health and safety of animals and human beings. In this study, a genetically stable Brucella rough RA343 strain was obtained by cross‐induction. The virulence and protective efficacy of RA343 were subsequently assessed. Overall, the RA343 strain is a promising novel
Linjiao Li, Guangzhi Zhang, Minghe Liu, Lang Lv, Xiaowei Peng, Yu Feng, Xiaotong Yang, Jiabo Ding, Chunhai Liu, Jianhua Qin, Peng Li, Hui Jiang, Xuezheng Fan   +12 more
wiley   +1 more source

Isolation, Identification and Molecular Characterization of Brucella abortus from Bovines

Journal of Pure and Applied Microbiology, 2017
Brucellosis is an important zoonosis and a significant cause of reproductive losses in animals. Abortion, placentitis, epididymitis and orchitis are the most common clinical manifestations in animals.
M.D. Shrimali, N.M. Shah, B.S. Chandel, H.C. Chauhan, S.S. Patel, K.B. Patel, B.K. Patel, A.G. Bhagat, S.I. Patel, A.I. Dadawala, J.D. Shah, Manish Rajgor, R.P. Pandya, A.C. Patel, M.A. Patel, J.K. Kala, M.G. Patel   +16 more
doaj   +1 more source

The role of NLRP3 and AIM2 in inflammasome activation during Brucella abortus infection

Seminars in Immunopathology, 2016
The innate immune system is essential for the detection and elimination of bacterial pathogens. Upon inflammasome activation, caspase-1 cleaves pro-IL-1β and pro-IL-18 to their mature forms IL-1β and IL-18, respectively, and the cell undergoes ...
F. Marim, Miriam M. Costa Franco, M. T. Gomes, M. C. Miraglia, G. Giambartolomei, S. Oliveira   +5 more
semanticscholar   +1 more source

Cetacean Host-Pathogen Interaction(s): Critical Knowledge Gaps [PDF]

, 2018
Within the broad range of viral and non-viral pathogens infecting cetaceans, Cetacean Morbillivirus (CeMV), Herpesvirus (HV), Brucella ceti, and Toxoplasma gondii are of special concern, due to their impact(s) on the health and conservation of free ...
Centelleghe, Cinzia, Di Guardo, Giovanni, Mazzariol, Sandro   +2 more
core   +2 more sources

Proteomic Analysis of Membrane Blebs of Brucella abortus 2308 and RB51 and Their Evaluation as an Acellular Vaccine

Frontiers in Microbiology, 2019
Membrane blebs are released from Gram-negative bacteria, however, little is known about Brucella blebs. This work pursued two objectives, the first was to determine and identify the proteins in the membrane blebs by proteomics and in silico analysis. The
Minerva Araiza-Villanueva, Eric Daniel Avila-Calderón, Eric Daniel Avila-Calderón, Leopoldo Flores-Romo, Juana Calderón-Amador, Nammalwar Sriranganathan, Hamzeh Al Qublan, Sharon Witonsky, Sharon Witonsky, Ma. Guadalupe Aguilera-Arreola, María del Socorro Ruiz-Palma, María del Socorro Ruiz-Palma, Enrico A. Ruiz, Francisco Suárez-Güemes, Zulema Gómez-Lunar, Araceli Contreras-Rodríguez   +15 more
doaj   +1 more source

Enhancing One Health outcomes using decision science and negotiation

Frontiers in Ecology and the Environment, Volume 23, Issue 4, May 2025.
One Health initiatives have advanced zoonotic disease management by recognizing the interconnectedness of three sectors of governance (human, ecosystem, and animal) and by identifying options that can improve full‐system health. Although One Health has had many successes, its full realization may be inhibited by a lack of strategies to overcome ...
Jonathan D Cook, Evan H Campbell Grant, Howard S Ginsberg, Diann J Prosser, Michael C Runge   +4 more
wiley   +1 more source

RecA and RadA Proteins of Brucella abortus Do Not Perform Overlapping Protective DNA Repair Functions following Oxidative Burst [PDF]

, 2006
Very little is known about the role of DNA repair networks in Brucella abortus and its role in pathogenesis. We investigated the roles of RecA protein, DNA repair, and SOS regulation in B. abortus.
Bellaire, Bryan H., Booth, Natha J., Elzer, Philip H., Ennis, Don G., Gee, Jason M., Kovach, Michael E., Roop, R. Martin II, Roux, Christelle M., Tsolis, Renee M.   +8 more
core   +2 more sources

A rapid minor groove binder PCR method for distinguishing the vaccine strain Brucella abortus 104M

BMC Veterinary Research, 2018
Background Brucellosis is a widespread zoonotic disease caused by Gram-negative Brucella bacteria. Immunisation with attenuated vaccine is an effective method of prevention, but it can interfere with diagnosis.
Wenlong Nan, Lide Qin, Yong Wang, Yueyong Zhang, Pengfei Tan, Yuqi Chen, Kairong Mao, Yiping Chen   +7 more
doaj   +1 more source