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Brucellosis is a zoonotic disease cause by pathogenic bacteria of the genus Brucella. The disease infects livestock mammals such as cows, goats, pigs, and including humans. Brucella abortus has several potential virulence factors, i.e.
Ratih Novita Praja +3 more
doaj +1 more source
Brucellosis remains a neglected disease inthe developing world: a call forinterdisciplinary action [PDF]
Brucellosis places significant burdens on the human healthcare system and limits the economic growth of individuals, communities, and nations where such development is especially important to diminish the prevalence of poverty.
A Fournier +46 more
core +1 more source
Background: Brucellosis is an emerging zoonotic disease worldwide. Brucella melitensis, Brucella abortus, Brucella suis, and Brucella canis are the main etiologic agents causing human brucellosis.
Kun Li +9 more
doaj +1 more source
The aim of this study is to determine the sensitivity of bacterial culture technique in the detection of Brucella abortus in milk samples of aborted cows.
Bashar Sadeq Noomy
doaj +1 more source
Ex vivo innate immune cytokine signature of enhanced risk of relapsing brucellosis. [PDF]
BackgroundBrucellosis, a zoonotic infection caused by one of the Gram-negative intracellular bacteria of the Brucella genus, is an ongoing public health problem in Perú.
Feldman, Kristyn E +9 more
core +3 more sources
Effects of live Brucella abortus strain 19 vaccine on reindeer
Twenty female and seven male reindeer (Rangifer tarandus) were vaccinated subcutaneously in the right shoulder with a 1-ml dose of approximately 1.2 x 108 colony forming units of Brucella abortus strain 19, the standard reduced dose for cattle.
Robert A. Dieterich, Jamie K. Morton
doaj +1 more source
Mitochondrial fusion protein 2 affects intracellular survival of brucella abortus a19 by regulating endoplasmic reticulum stress and apoptosis [PDF]
Mitochondrial fusion protein 2 (MFN2) deficiency has been shown to hinder the survival of bacteria in macrophages. Endoplasmic reticulum stress and apoptosis are vital defense mechanisms against Brucella infection, but the specific role of MFN2 in ...
Zhenyu XU +5 more
doaj +1 more source
Btp Proteins from Brucella abortus Modulate the Lung Innate Immune Response to Infection by the Respiratory Route [PDF]
Although inhalation of infected aerosols is a frequent route for Brucella infection in humans, it rarely causes pulmonary clinical manifestations, suggesting a mild or nearly absent local inflammatory response.
Baldi, Pablo Cesar +6 more
core +1 more source
BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43
This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan +13 more
wiley +1 more source
Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu +5 more
wiley +1 more source

