Results 1 to 10 of about 5,811 (198)

Mining the Flavoproteome of Brucella ovis, the Brucellosis Causing Agent in Ovis aries [PDF]

Microbiology Spectrum, 2022
Flavoproteins are a diverse class of proteins that are mostly enzymes and contain as cofactors flavin mononucleotide (FMN) and/or flavin adenine dinucleotide (FAD), which enable them to participate in a wide range of physiological reactions.
Martha Minjárez-Sáenz, Marta Martínez-Júlvez, Inmaculada Yruela, Milagros Medina   +3 more
doaj   +9 more sources

The Transcriptional Regulator MucR, but Not Its Controlled Acid-Activated Chaperone HdeA, Is Essential for Virulence and Modulates Surface Architecture and Properties in Brucella ovis PA [PDF]

Frontiers in Veterinary Science, 2022
Brucella ovis is a non-zoonotic bacterium causing contagious epididymitis and other genital lesions in rams and responsible for significant economic losses in sheep-breeding areas.
Beatriz Tartilán-Choya, Rebeca S. Sidhu-Muñoz, Rebeca S. Sidhu-Muñoz, Nieves Vizcaíno, Nieves Vizcaíno   +4 more
doaj   +4 more sources

A Brucella melitensis H38ΔwbkF rough mutant protects against Brucella ovis in rams [PDF]

Veterinary Research, 2022
Brucella melitensis and Brucella ovis are gram-negative pathogens of sheep that cause severe economic losses and, although B. ovis is non-zoonotic, B. melitensis is the main cause of human brucellosis. B.
Pilar M. Muñoz, Raquel Conde-Álvarez, Sara Andrés-Barranco, María-Jesús de Miguel, Amaia Zúñiga-Ripa, Beatriz Aragón-Aranda, Miriam Salvador-Bescós, Estrella Martínez-Gómez, Maite Iriarte, Montserrat Barberán, Nieves Vizcaíno, Ignacio Moriyón, José M. Blasco   +12 more
doaj   +10 more sources

The Three Flagellar Loci of Brucella ovis PA Are Dispensable for Virulence in Cellular Models and Mice [PDF]

Frontiers in Veterinary Science, 2020
Brucella ovis is a facultative intracellular bacterium that causes a non-zoonotic ovine brucellosis mainly characterized by male genital lesions and is responsible for important economic losses in sheep farming areas.
Rebeca S. Sidhu-Muñoz, Rebeca S. Sidhu-Muñoz, Carmen Tejedor, Nieves Vizcaíno, Nieves Vizcaíno   +4 more
doaj   +4 more sources

Demonstration of IS711 transposition in Brucella ovis and Brucella pinnipedialis [PDF]

BMC Microbiology, 2008
Background The Brucella genome contains an insertion sequence (IS) element called IS711 or IS6501, which is specific to the genus. The copy number of IS711 varies in the genome of the different Brucella species, ranging from 7 in B.
García-Lobo Juan M, Ocampo-Sosa Alain A
doaj   +8 more sources

The outer membrane proteins based seroprevalence strategy for Brucella ovis natural infection in sheep [PDF]

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionThe diagnosis of brucellosis largely relies on tiger red plate agglutination test (RBPT). However, it is difficult to distinguish between natural infection antibody positive and vaccination antibody positive, nevertheless, the identification ...
Tao Zhang, Yu Wang, Yin Li, Tingting Qi, Zhirong Yue, Lili Cao, Bo Zhou, Huping Jiao   +7 more
doaj   +2 more sources

Characterization of three predicted zinc exporters in Brucella ovis identifies ZntR-ZntA as a powerful zinc and cadmium efflux system not required for virulence and unveils pathogenic Brucellae heterogeneity in zinc homeostasis [PDF]

Frontiers in Veterinary Science, 2023
Brucella ovis causes non-zoonotic ovine brucellosis of worldwide distribution and is responsible for important economic losses mainly derived from male genital lesions and reproductive fails.
Beatriz Tartilán-Choya, Carmen Tejedor, Raquel Conde-Álvarez, Pilar María Muñoz, Pilar María Muñoz, Nieves Vizcaíno, Nieves Vizcaíno   +6 more
doaj   +2 more sources

Crystal structure of a short-chain dehydrogenase from Brucella ovis with apo and coenzyme NAD⁺-bound protomer chains. [PDF]

Acta Crystallogr F Struct Biol Commun
This article describes the structural characterization of a short‐chain dehydrogenase from the pathogenic bacterium Brucella ovis. In this manuscript, two structures are described: the structure of the apo protein and a structure containing the coenzyme NAD+.Short‐chain dehydrogenases (SDRs) are a family of NAD(P)‐dependent enzymes involved in redox ...
Zupko SP, Konstanty AT, Mayclin SJ, Choi R, Serbzhinskiy D, Robles E, Moses V, Barrett LK, Van Voorhis WC, Edwards TE, Myler PJ, Torelli AT, French JB, Hicks KA.   +13 more
europepmc   +2 more sources

Disruption of pyruvate phosphate dikinase in Brucella ovis PA CO2-dependent and independent strains generates attenuation in the mouse model [PDF]

Veterinary Research, 2020
Brucella ovis is a non-zoonotic rough Brucella that causes genital lesions, abortions and increased perinatal mortality in sheep and is responsible for important economic losses worldwide. Research on virulence factors of B.
Nieves Vizcaíno, Lara Pérez-Etayo, Raquel Conde-Álvarez, Maite Iriarte, Ignacio Moriyón, Amaia Zúñiga-Ripa   +5 more
doaj   +2 more sources

The CO2-dependence of Brucella ovis and Brucella abortus biovars is caused by defective carbonic anhydrases [PDF]

Veterinary Research, 2018
Brucella bacteria cause brucellosis, a major zoonosis whose control requires efficient diagnosis and vaccines. Identification of classical Brucella spp.
Lara Pérez-Etayo, María Jesús de Miguel, Raquel Conde-Álvarez, Pilar M. Muñoz, Mammar Khames, Maite Iriarte, Ignacio Moriyón, Amaia Zúñiga-Ripa   +7 more
doaj   +2 more sources