Demonstration of IS
BMC Microbiology, 2008 Background The Brucella genome contains an insertion sequence (IS) element called IS711 or IS6501, which is specific to the genus. The copy number of IS711 varies in the genome of the different Brucella species, ranging from 7 in B.
García-Lobo Juan M, Ocampo-Sosa Alain A
doaj +5 more sources
Disruption of pyruvate phosphate dikinase in Brucella ovis PA CO2-dependent and independent strains generates attenuation in the mouse model [PDF]
Veterinary Research, 2020 Brucella ovis is a non-zoonotic rough Brucella that causes genital lesions, abortions and increased perinatal mortality in sheep and is responsible for important economic losses worldwide. Research on virulence factors of B.
Nieves Vizcaíno +5 more
doaj +2 more sources
Reversion of a RND transporter pseudogene reveals latent stress resistance potential in Brucella ovis. [PDF]
PLoS GeneticsSmall-molecule screens can advance therapeutic discovery and uncover new features of pathogen biology. Through a luminescence-based screen, we identified clinically approved dihydropyridines that impaired fitness of the intracellular pathogen Brucella ...
Thomas Kim +7 more
doaj +2 more sources
Rev1 wbdR tagged vaccines against Brucella ovis [PDF]
Veterinary Research, 2019 Sheep brucellosis is a worldwide extended disease caused by B. melitensis and B. ovis, two species respectively carrying smooth or rough lipopolysaccharide. Vaccine B. melitensis Rev1 is used against B. melitensis and B.
Beatriz Aragón-Aranda +8 more
doaj +2 more sources
The CO2-dependence of Brucella ovis and Brucella abortus biovars is caused by defective carbonic anhydrases [PDF]
Veterinary Research, 2018 Brucella bacteria cause brucellosis, a major zoonosis whose control requires efficient diagnosis and vaccines. Identification of classical Brucella spp.
Lara Pérez-Etayo +7 more
doaj +2 more sources
Brucella ovis mutant in ABC transporter protects against Brucella canis infection in mice and it is safe for dogs. [PDF]
PLoS ONE, 2020 BACKGROUND/OBJECTIVES:Vaccination is the most important tool for controlling brucellosis, but currently there is no vaccine available for canine brucellosis, which is a zoonotic disease of worldwide distribution caused by Brucella canis. This study aimed
Camila Eckstein +14 more
doaj +2 more sources
Ovine epididymitis – a neglected notifiable disease in Germany: a case report [PDF]
BMC Veterinary ResearchBackground Ovine contagious epididymitis is an infectious disease caused by Brucella ovis. Its occurrence in EU member states must be reported to the relevant authorities.
Hanka Brangsch +6 more
doaj +2 more sources
Characterization of Cell Envelope Multiple Mutants of Brucella ovis and Assessment in Mice of Their Vaccine Potential [PDF]
Frontiers in Microbiology, 2018 Brucella ovis is a non-zoonotic Brucella species lacking specific vaccine. It presents a narrow host range, a unique biology relative to other Brucella species, and important distinct surface properties.
Rebeca Singh Sidhu-Muñoz +8 more
doaj +2 more sources
Molecular Detection of Brucella ovis in Aborted Ewes in Sulaimani Governorate [PDF]
Basrah Journal of Veterinary Research, 2021 Abortion causes substantial economic losses in sheep flocks. In addition to financial compensation, abortion is a sharp aspect of public health. Brucella, Campylobacter, Salmonella and Chlamydia are the most examples of diseases associated with the ...
Eman Arif
doaj +1 more source
Crystal structure of a short-chain dehydrogenase from Brucella ovis with apo and coenzyme NAD<sup>+</sup>-bound protomer chains. [PDF]
Acta Crystallogr F Struct Biol CommunThis article describes the structural characterization of a short‐chain dehydrogenase from the pathogenic bacterium Brucella ovis. In this manuscript, two structures are described: the structure of the apo protein and a structure containing the coenzyme NAD+.Short‐chain dehydrogenases (SDRs) are a family of NAD(P)‐dependent enzymes involved in redox ...
Zupko SP +13 more
europepmc +2 more sources