Rev1 wbdR tagged vaccines against Brucella ovis [PDF]
Veterinary Research, 2019 Sheep brucellosis is a worldwide extended disease caused by B. melitensis and B. ovis, two species respectively carrying smooth or rough lipopolysaccharide. Vaccine B. melitensis Rev1 is used against B. melitensis and B.
Beatriz Aragón-Aranda +8 more
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Characterization of Cell Envelope Multiple Mutants of Brucella ovis and Assessment in Mice of Their Vaccine Potential [PDF]
Frontiers in Microbiology, 2018 Brucella ovis is a non-zoonotic Brucella species lacking specific vaccine. It presents a narrow host range, a unique biology relative to other Brucella species, and important distinct surface properties.
Rebeca Singh Sidhu-Muñoz +8 more
doaj +4 more sources
Brucella ovis mutant in ABC transporter protects against Brucella canis infection in mice and it is safe for dogs. [PDF]
PLoS ONE, 2020 BACKGROUND/OBJECTIVES:Vaccination is the most important tool for controlling brucellosis, but currently there is no vaccine available for canine brucellosis, which is a zoonotic disease of worldwide distribution caused by Brucella canis. This study aimed
Camila Eckstein +14 more
doaj +3 more sources
Genome degradation in Brucella ovis corresponds with narrowing of its host range and tissue tropism. [PDF]
PLoS ONE, 2009 Brucella ovis is a veterinary pathogen associated with epididymitis in sheep. Despite its genetic similarity to the zoonotic pathogens B. abortus, B. melitensis and B. suis, B. ovis does not cause zoonotic disease.
Renee M Tsolis +19 more
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Reversion of a RND transporter pseudogene reveals latent stress resistance potential in Brucella ovis. [PDF]
PLoS GeneticsSmall-molecule screens can advance therapeutic discovery and uncover new features of pathogen biology. Through a luminescence-based screen, we identified clinically approved dihydropyridines that impaired fitness of the intracellular pathogen Brucella ...
Thomas Kim +7 more
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An HWE-Family Histidine Kinase Modulates Brucella Cell Envelope Properties and Host Innate Immune Response. [PDF]
Mol MicrobiolThe HWE‐family histidine kinase PhyK regulates the cell envelope structure of the intracellular pathogen Brucella ovis and affects how the host immune system responds to this bacterium. Deletion of phyK alters bacterial survival in the face of detergent stress and reduces immune activation in infected macrophages.
Chen X +6 more
europepmc +2 more sources
Brucella ovis Cysteine Biosynthesis Contributes to Peroxide Stress Survival and Fitness in the Intracellular Niche. [PDF]
Infect Immun, 2021 Varesio LM, Fiebig A, Crosson S.
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Molecular Detection of Brucella ovis in Aborted Ewes in Sulaimani Governorate [PDF]
Basrah Journal of Veterinary Research, 2021 Abortion causes substantial economic losses in sheep flocks. In addition to financial compensation, abortion is a sharp aspect of public health. Brucella, Campylobacter, Salmonella and Chlamydia are the most examples of diseases associated with the ...
Eman Arif
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Comparative proteomic analysis of outer membrane vesicles from Brucella suis, Brucella ovis, Brucella canis and Brucella neotomae. [PDF]
Arch Microbiol, 2021 Gram-negative bacteria release nanovesicles, called outer membrane vesicles (OMVs), from their outer membrane. Proteomics has been used to determine their composition. OMVs contain proteins able to elicit an immune response, so they have been proposed as a model to develop acellular vaccines. In this study, OMVs of Brucella suis, B. ovis, B. canis, and
Socorro Ruiz-Palma MD +9 more
europepmc +4 more sources
First study of Brucella ovis antibodies in purebred sheep flocks in the State of Parana, Brazil
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021 Brucella ovis, a non-zoonotic species, is the etiological agent of ovine brucellosis, an infectious disease of clinical or subclinical occurrence in sheep flocks.
J.V.P. Barreto +6 more
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