Results 91 to 100 of about 2,212,387 (300)

Ventricular tachycardia associated with lacosamide co-medication in drug-resistant epilepsy. [PDF]

, 2012
We report a case of sustained ventricular tachycardia following the initiation of lacosamide as adjunctive epilepsy treatment. A 49-year-old male with intractable frontal lobe seizures experienced severe ventricular tachycardia following the addition of ...
DeGiorgio, Andrew C, DeGiorgio, Christopher M, Desso, Tamara E, Lee, Lance   +3 more
core   +1 more source

A Case of STEMI Masquerading Brugada Syndrome: Emphasizing the Importance of Clinical Decision Making in Emergencies

Journal of Investigative Medicine High Impact Case Reports, 2021
Brugada syndrome is a rare arrhythmogenic syndrome that is associated with an increased risk of ventricular fibrillation and sudden cardiac death. Electrocardiographic findings include patterns similar to a right bundle branch block (RBBB) and persistent
Nirmal Guragai MD, Rahul Vasudev MD, Dhaval Shah MD, Balraj Singh MD, Parminder Kaur MD, Ashen Fernando MD, Fayez Shamoon MD, Raja Pullatt MD, Meherwan Joshi MD, Preet Randhawa MD   +9 more
doaj   +1 more source

Electrical Storms in Brugada Syndrome: Review of Pharmacologic and Ablative Therapeutic Options [PDF]

, 2005
Electrical storm occurring in a patient with the Brugada syndrome is an exceptional but malignant and potentially lethal event. Efficient therapeutic solutions should be known and urgently applied because of the inability of usual antiarrhythmic means in
Haïssaguerre, M, Hocini, M, Maury, P
core   +2 more sources

Predicting cardiac electrical response to sodium-channel blockade and Brugada syndrome using polygenic risk scores

European Heart Journal, 2019
Aims Sodium-channel blockers (SCBs) are associated with arrhythmia, but variability of cardiac electrical response remains unexplained. We sought to identify predictors of ajmaline-induced PR and QRS changes and Type I Brugada syndrome (BrS ...
R. Tadros, H. Tan, S. el Mathari, J. Kors, P. Postema, N. Lahrouchi, L. Beekman, Milena Radivojkov-Blagojević, A. Amin, T. Meitinger, M. Tanck, A. Wilde, C. Bezzina   +12 more
semanticscholar   +1 more source

Epilepsy–heart syndrome: Concept, clinical context, and opportunity for integrated care

Epilepsia, Volume 66, Issue 6, Page 1830-1837, June 2025.
Abstract In this concept paper, we introduce epilepsy‐heart syndrome as a shared burden of illness between epilepsy and cardiac disorders. This pragmatic definition is agnostic of which condition came first (the epilepsy or the cardiac disorder), recognising that these conditions can each serve as a risk factor for the other owing to a bidirectional ...
Gashirai K. Mbizvo, Iain E. Buchan, Anthony G. Marson, Gregory Y. H. Lip   +3 more
wiley   +1 more source

Abnormal ECG Findings in Athletes: Clinical Evaluation and Considerations. [PDF]

, 2019
PURPOSE OF REVIEW: Pre-participation cardiovascular evaluation with electrocardiography is normal practice for most sporting bodies. Awareness about sudden cardiac death in athletes and recognizing how screening can help identify vulnerable athletes have
A Biffi, A Biffi, A D’Silva, A D’Silva, A Magalski, A Malhotra, A Malhotra, A Malhotra, A Merghani, A Morshedi-Meibodi, A Pelliccia, A Pelliccia, A Zaidi, A Zaidi, A Zorzi, A Zorzi, A Zorzi, AD Desai, AL Aro, AL Rao, AO Usoro, BJ Maron, BJ Maron, C Antzelevitch, C Calore, C Daubert, C Miles, D Corrado, D Corrado, D Corrado, D Corrado, F D’Ascenzi, F Migliore, F Schnell, FI Marcus, G Finocchiaro, G Malfatto, G Mcclean, GJ Klein, GJ Klein, H Dhutia, H Morita, HUH Virk, J Basu, J Ehtisham, J Marek, J Novak, J Pei, J Steinfurt, JA Drezner, JA Drezner, KG Harmon, KM Park, L Calò, L Verdile, M Brosnan, M Papadakis, M Papadakis, M Sadron Blaye-Felice, MAE Haukilahti, Mark Abela, MG Wilson, MI Cohen, MJ Ackerman, MJ Brosnan, N Chandra, N Panhuyzen-goedkoop, N Sheikh, P Banankhah, PG Postema, PT Matusik, RE Bent, RE Eckart, S Gati, S Kapa, S Masrur, S Peters, S Sharma, S Viskin, Sanjay Sharma, SEE Page, T Senturk, X Li, YH Lee   +83 more
core   +1 more source

A Variant of Brugada Syndrome [PDF]

Baylor University Medical Center Proceedings, 2017
Brugada syndrome is an inherited disorder that can present with syncope, cardiac arrest, or sudden cardiac death. Multiple genetic mutations have been described that cause this disease. We present a 56-year-old man who sustained an out-of-hospital cardiac arrest, was resuscitated, and was found to have typical features of the Brugada criteria on the ...
Enoch Agunanne, Mohamed Teleb, Maryna Popp Switzer, Aamer Abbas   +3 more
openaire   +3 more sources

Identification of N-terminal protein acetylation and arginine methylation of the voltage-gated sodium channel in end-stage heart failure human heart [PDF]

, 2014
The α subunit of the cardiac voltage-gated sodium channel, Naᵥ1.5, provides the rapid sodium inward current that initiates cardiomyocyte action potentials.
Batlle, Montserrat, Beltran-Alvarez, Pedro, Brugada, Ramon, Chiva, Cristina, Chiva, Critina, Pagans, Sara, Perez-Serra, Alexandra, Perez-Villa, Felix, Pérez-Serra, Alexandra, Pérez-Villa, Félix, Sabido, Eduard, Sabidó, Eduard, Schulte, Uwe, Tarradas, Anna   +13 more
core   +1 more source

Parkinson's disease‐linked Kir4.2 mutation R28C leads to loss of ion channel function

The Journal of Physiology, Volume 603, Issue 12, Page 3499-3518, 15 June 2025.
Abstract figure legend Pathogenic impact of the PD‐linked Kir4.2R28C mutation on Kir4.2 channel proteostasis and function. The Kir4.2R28C mutation, identified in a familial Parkinson's disease (PD) pedigree, leads to a near‐complete loss of potassium channel function and exerts a significant dominant‐negative effect.
Xiaoyi Chen, Rocio K. Finol‐Urdaneta, Mo Chen, Alex M. Sykes, Bingmiao Gao, Jamila Iqbal, David J. Adams, George D. Mellick, Linlin Ma   +8 more
wiley   +1 more source

A case of Brugada syndrome [PDF]

QJM, 2012
A 48-year-old man presented himself to our clinic due to an episode of a sense of dizziness and presyncope while he was standing from which he recovered after 5 min of adopting the supine position. The patient did not have related palpitations, chest pain or shortness of breath and was feeling fully recovered at the time of the interview. The patient’s
A.L. Aguilar-Shea, C. Gallardo-Mayo
openaire   +3 more sources