Results 71 to 80 of about 1,233,631 (221)

Genes previously associated with Brugada syndrome.

, 2022
Genes previously associated with Brugada syndrome.
Ricardo Lage (6392375), María Sabater-Molina (10302275), Juan Jiménez-Jáimez (489480), Laura Martínez-Campelo (10330403), Eva Ramos-Luis (12174423), Raquel Cruz (10330406), María Álvarez-Barredo (320199), Pablo Peñafiel-Verdú (12174426), Moisés Rodríguez-Mañero (480185), Alejandro Blanco-Verea (113187), María Brion (12174429), Isabel Moscoso (3413960)   +11 more
core   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Characteristics of Patients with Spontaneous Versus Drug-Induced Brugada Electrocardiogram: Sub-Analysis From the SABRUS. [PDF]

, 2023
Brugada syndrome; electrocardiography; heart arrest; syncope; ventricular ...
Casado-Arroyo, R, Denjoy, I, Postema, Pieter G, Yan, Gan-Xin, Giustetto, C, Sarquella-Brugada, G, Takagi, M, Brugada, Josep, Gaita, F, Corrado, D, Leshem, Eran, Andorin, Antoine, Calo, Leonardo, Conte, G, Tfelt-Hansen, Jacob, Sarquella-Brugada, Georgia, Gourraud, Jean-Baptiste, Andorin, A, Mazzanti, A, Maeda, Shingo, Kamakura, T, Kusano, Kengo, Priori, SG, Aiba, T, Hirao, K, Probst, V, Takahashi, Yoshihide, Leenhardt, Antoine, Kim, Sung-Hwan, Wijeyeratne, Yanushi YD, Arbelo, E, Brugada, J, Wilde, Arthur A.M., Huang, Zhengrong, Behr, Elijah Raphael, Yan, G-X, Leshem, E, Milman, A, Delise, P, Kusano, Kengo KF, Kusano, KF, Takahashi, Y, Michowitz, Y, Veltmann, C, Priori, Silvia, Leenhardt, A, Probst, Vincent, Wilde, AAM, Arbelo, Elena, Sabbag, A, Aiba, Takeshi, Juang, JJ, Denjoy, Isabelle, Wilde, Arthur A M, Wijeyeratne, Yanushi D, Gaita, Fiorenzo, Delise, Pietro, Brugada, R, Mabo, Philippe, Casado-Arroyo, Ruben, Brugada, P, Takagi, Masahiko, Wijeyeratne, YD, Mizusawa, Yuka, Hirao, Kenzo, Kim, SungHwan, Postema, PG, Behr, Elijah R, Kusano, Kengo F, Tfelt-Hansen, J, Belhassen, Bernard, Sabbag, Avi, Nam, Gi-Byoung, Conte, Giulio, Wijeyeratne, Yanushi, Behr, Elijah, Champagne, J, Michowitz, Yoav, Corrado, Domenico, Belhassen, B, Maeda, S, Milman, Anat, Kamakura, Tsukasa, Sacher, F, Veltmann, Christian, Postema, Pieter, Nam, G-B, Calo, L, Juang, Jimmy Jm, Priori, Silvia G, Mabo, P, Huang, Z, Kim, S-H, Giustetto, Carla, Mizusawa, Y, Sacher, Frederic, Gourraud, J-B, Champagne, Jean, Brugada, Ramon, Mazzanti, Andrea, Behr, ER, Brugada, Pedro, Casado Arroyo, Ruben, Anat Milman, Vincent Probst, Ramon Brugada, Elena Arbelo, Philippe Mabo, Josep Brugada, Antoine Leenhardt, Yoshihide Takahashi, Andrea Mazzanti, Jean Champagne, Domenico Corrado, Jacob Tfelt-Hansen, Leonardo Calo, Frederic Sacher, Bernard Belhassen, Gi-Byoung Nam, Yuka Mizusawa, Carla Giustetto, Christian Veltmann, Takeshi Aiba, Antoine Andorin, Pieter G. Postema, Sung-Hwan Kim, Tsukasa Kamakura, Pietro Delise, Fiorenzo Gaita, Zhengrong Huang, Gan-Xin Yan, Kenzo Hirao, Arthur A.M. Wilde, Eran Leshem, Avi Sabbag, Pedro Brugada, Giulio Conte, Georgia Sarquella-Brugada, Yoav Michowitz, Silvia G. Priori, Jean-Baptiste Gourraud, Yanushi D. Wijeyeratne, Elijah R. Behr, Jimmy JM Juang, Isabelle Denjoy, Shingo Maeda, Kengo F. Kusano, Ruben Casado-Arroyo, Masahiko Takagi   +148 more
core   +1 more source

Fever Unmasked Brugada Syndrome in Pediatric Patient: A Case Report

Clinical Practice and Cases in Emergency Medicine, 2020
Introduction: Brugada syndrome is an arrhythmogenic disorder that is a known cause of sudden cardiac death. It is characterized by a pattern of ST segment elevation in the precordial leads on an electrocardiogram (EKG) due to a sodium channelopathy. Case
Orhay Mirzapolos, Perry Marshall, April Brill   +2 more
doaj   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Brugada syndrome: 12 years of progression. [PDF]

, 2004
Brugada syndrome is increasingly being recognized in clinical medicine. What started as an electrocardiographic curiosity has become an important focus of attention for individuals working in the different disciplines related to sudden cardiac death ...
Antzelevitch, Charles, Hong, Kui, Brugada, Ramon, Brugada, Josep, Brugada, Pedro, Ohe, Tohru   +5 more
core   +1 more source

The interplay between dynamic regulation of ion‐channel gating and trafficking in cardiac arrhythmogenesis

The Journal of Physiology, EarlyView.
Abstract figure legend Cardiac cellular electrophysiology is modulated by multiple factors, including temperature, extracellular K+, heart rate/pacing frequency, and drugs. These modulators can have distinct effects on ion‐channel gating and transcription/trafficking over time.
Stefan Meier, Anna S. Savchenko, Paul G. A. Volders, Jordi Heijman   +3 more
wiley   +1 more source

A Variant of Brugada Syndrome [PDF]

Baylor University Medical Center Proceedings, 2017
Brugada syndrome is an inherited disorder that can present with syncope, cardiac arrest, or sudden cardiac death. Multiple genetic mutations have been described that cause this disease. We present a 56-year-old man who sustained an out-of-hospital cardiac arrest, was resuscitated, and was found to have typical features of the Brugada criteria on the ...
Maryna Popp, Switzer, Mohamed, Teleb, Enoch, Agunanne, Aamer, Abbas   +3 more
openaire   +2 more sources

Adjusting for Medication Use in GWAS and Its Impact on Mendelian Randomisation Analyses: An Example of Systolic Blood Pressure in UK Biobank

Genetic Epidemiology, Volume 50, Issue 8, December 2026.
ABSTRACT Medication use is common in large‐scale population cohorts, and can modify phenotypic traits of interest. This can potentially bias effect estimates in genome‐wide association studies (GWAS) and impact downstream analyses such as Mendelian randomisation (MR). The best approach to account for medication use in GWAS is unclear. In this study, we
Aaron Jun Yi Yap, Aimee L. Hanson, Gareth J. Griffith, Eleanor Sanderson   +3 more
wiley   +1 more source

Analysis of a Family with Brugada Syndrome and Sudden Cardiac Death Caused by a Novel Mutation of SCN5A

Cardiology Research and Practice, 2022
Background. Brugada syndrome is a hereditary cardiac disease associated with mutations in ion channel genes. The clinical features include ventricular fibrillation, syncope, and sudden cardiac death.
Yao-Bin Zhu, Jian-Hui Zhang, Yuan-Yuan Ji, Ya-Nan Hu, Han-Lu Wang, Dan-Dan Ruan, Xiao-Rong Meng, Xin-Fu Lin, Jie-Wei Luo, Wei Chen   +9 more
doaj   +1 more source