Results 61 to 70 of about 2,471,143 (310)

Genetics of Brugada syndrome [PDF]

Journal of Human Genetics, 2015
The Brugada syndrome is characterized by unique 'coved-type' ST-segment elevation in the right precordial leads of electrocardiogram and ventricular fibrillation, and is responsible for 4 to 12% of sudden cardiac death in the general population. The frequency is higher in Southeast Asia including Japan compared with Western countries.
Hiroshi, Watanabe, Tohru, Minamino
openaire   +2 more sources

Brugada syndrome with a novel missense mutation in SCN5A gene: A case report from Bangladesh

Indian Heart Journal, 2014
Brugada syndrome is an inherited cardiac arrhythmia that follows autosomal dominant transmission and can cause sudden death. We report a case of Brugada syndrome in a 55-year-old male patient presented with recurrent palpitation, atypical chest pain and ...
Md. Zahidus Sayeed, Md. Abdus Salam, Md. Zahirul Haque, A.K.M. Monwarul Islam   +3 more
doaj   +1 more source

Brugada phenocopy or congenital Brugada syndrome in a patient with spontaneous pneumopericardium and pericarditis

Journal of Arrhythmia, 2021
Brugada syndrome (BrS) is characterized by coved ST segment elevation in the right precordial lead (V1‐V3). Previous reports have described type‐1 or type‐2 Brugada ECG pattern as a Brugada phenocopy (BrP) in various clinical condition and once the ...
Pichmanil Khmao, Vannak Long, No Ku, Sivutha Lim   +3 more
doaj   +1 more source

Hyperkalemia-induced brugada phenocopy: A rare electrocardiogram manifestation

Journal of the Practice of Cardiovascular Sciences, 2022
Hyperkalemia-induced Brugada ECG pattern is rare. Although the association of hyperkalemia with Brugada pattern is a known entity, it is also very important to be aware of this presentation as the treatment of this Brugada Phenocopy is different from ...
Satyajit Singh, Chandra Prakash Thakur, Surendra Naik, Muneshwar Kumar   +3 more
doaj   +1 more source

Incorporating Latent Variables Using Nonnegative Matrix Factorization Improves Risk Stratification in Brugada Syndrome

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background A combination of clinical and electrocardiographic risk factors is used for risk stratification in Brugada syndrome. In this study, we tested the hypothesis that the incorporation of latent variables between variables using nonnegative matrix ...
G. Tse, Jiandong Zhou, Sharen Lee, Tong Liu, G. Bazoukis, P. Mililis, I. Wong, Cheng Chen, Yunlong Xia, T. Kamakura, T. Aiba, K. Kusano, Qingpeng Zhang, K. Letsas   +13 more
semanticscholar   +1 more source

Genetic Biomarkers in the Risk Assessment of Sudden Cardiac Events: A Personalized Approach

iNew Medicine, EarlyView.
Genetic insights into the risk assessment of sudden cardiac events. ABSTRACT Sudden cardiac events are the leading cause of death worldwide. Conventional risk stratification methods, which largely depend on clinical history, imaging, and electrocardiography, are usually inadequate for identifying high‐risk individuals, especially those without visible ...
Shrikant Verma, Sushma Verma, Mohammad Abbas, Tabrez Faruqui, Bashir Ahmad Mir, Farzana Mahdi   +5 more
wiley   +1 more source

Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center study

Journal of Arrhythmia, 2013
Background: Brugada syndrome is a distinct form of idiopathic ventricular fibrillation. We retrospectively investigated the incidence and clinical implications of supraventricular tachyarrhythmia in patients with Brugada syndrome. Methods: We reviewed 69
Kimie Ohkubo, Ichiro Watanabe, Yasuo Okumura, Masayoshi Kofune, Koichi Nagashima, Hiroaki Mano, Kazumasa Sonoda, Toshiko Nakai, Satoshi Kunimoto, Yuji Kasamaki, Atsushi Hirayama, Naokata Sumitomo, Tomohiro Nakayama   +12 more
doaj   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

The Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan, Jenna Craddock, Tingting Gong, Ruth J Lyons, Igor Stevanovski, Sanjog R Chintalaphani, Ira W Deveson, Weerachai Jaratlerdsiri, Kishore R Kumar, Vanessa M Hayes   +9 more
wiley   +1 more source

Integration of “Omics” Strategies for Biomarkers Discovery and for the Elucidation of Molecular Mechanisms Underlying Brugada Syndrome [PDF]

, 2018
Purpose: The Brugada syndrome (BrS) is a severe inherited cardiac disorder. Given the high genetic and phenotypic heterogeneity of this disease, three different “omics” approaches are integrated in a synergic way to elucidate the molecular mechanisms ...
Oliva A., Curcio A., Tamme L., Campuzano O., Brugada R., Scumaci D., Pascali V. L., Ricci P., Fiumara C. V., Cuda G., Brugada J., Iglesias A., Casu G., Indolfi C., Olivo E., Coll M., Ausania F., Concolino A., Berne P.   +18 more
core   +2 more sources

Safety and Performance of INVICTA DF4 Ventricular Defibrillation Lead: Results From APOLLO Prospective Multicenter Study

Pacing and Clinical Electrophysiology, EarlyView.
Abstract Background Implantable cardioverter‐defibrillator (ICD) therapy relies on reliable right ventricular leads for pacing, sensing, and defibrillation. The INVICTA DF4 lead is an active‐fixation, quadripolar design intended to optimize implant workflow and long‐term safety and performance. Methods APOLLO was a prospective, multicenter, single‐arm,
Klaus K. Witte, Juan Gabriel Martínez, Mário M. Oliveira, Alberto Barrera, Maite Izquierdo, Cosimo Mandurino, Maria Emilce Trucco, José Juan García Salvador, Antoine Dompnier, Frédéric Jean, Pablo J. Sánchez Millán, Carsten Israel, Maria Martino, Pedro Marques   +13 more
wiley   +1 more source