Results 31 to 40 of about 9,398 (181)

Induced Brugada syndrome: Possible sources of arrhythmogenesis

open access: yesRevista Portuguesa de Cardiologia, 2017
Brugada syndrome is an inherited cardiac condition with the potential for development of life-threatening arrhythmias in relatively young individuals without significant structural cardiac abnormalities. The condition is characterized by a distinct coved-
Gonçalo Tomé, João Freitas
doaj   +1 more source

Brugada syndrome unmasked by dengue fever

open access: yesClinical Case Reports, 2023
Key Clinical Message Understanding the circumstances, leading to unmasking of hidden Brugada syndrome is essential for the practicing clinician and the patients so that they are informed adequately to seek prompt medical attention.
Lokesh Koumar Sivanandam   +5 more
doaj   +1 more source

Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center study

open access: yesJournal of Arrhythmia, 2013
Background: Brugada syndrome is a distinct form of idiopathic ventricular fibrillation. We retrospectively investigated the incidence and clinical implications of supraventricular tachyarrhythmia in patients with Brugada syndrome. Methods: We reviewed 69
Kimie Ohkubo   +12 more
doaj   +1 more source

Brugada phenocopy or congenital Brugada syndrome in a patient with spontaneous pneumopericardium and pericarditis

open access: yesJournal of Arrhythmia, 2021
Brugada syndrome (BrS) is characterized by coved ST segment elevation in the right precordial lead (V1‐V3). Previous reports have described type‐1 or type‐2 Brugada ECG pattern as a Brugada phenocopy (BrP) in various clinical condition and once the ...
Pichmanil Khmao   +3 more
doaj   +1 more source

Hyperkalemia-induced brugada phenocopy: A rare electrocardiogram manifestation

open access: yesJournal of the Practice of Cardiovascular Sciences, 2022
Hyperkalemia-induced Brugada ECG pattern is rare. Although the association of hyperkalemia with Brugada pattern is a known entity, it is also very important to be aware of this presentation as the treatment of this Brugada Phenocopy is different from ...
Satyajit Singh   +3 more
doaj   +1 more source

Genetics of Brugada syndrome [PDF]

open access: yesJournal of Human Genetics, 2015
The Brugada syndrome is characterized by unique 'coved-type' ST-segment elevation in the right precordial leads of electrocardiogram and ventricular fibrillation, and is responsible for 4 to 12% of sudden cardiac death in the general population. The frequency is higher in Southeast Asia including Japan compared with Western countries.
Hiroshi, Watanabe, Tohru, Minamino
openaire   +2 more sources

The Genetics of Brugada Syndrome

open access: yesAnnual Review of Genomics and Human Genetics, 2022
Brugada syndrome is a heritable channelopathy characterized by a peculiar electrocardiogram (ECG) pattern and increased risk of cardiac arrhythmias and sudden death. The arrhythmias originate because of an imbalance between the repolarizing and depolarizing currents that modulate the cardiac action potential. Even if an overt structural cardiomyopathy
Marina, Cerrone   +2 more
openaire   +2 more sources

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay   +3 more
wiley   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam   +3 more
wiley   +1 more source

Brugada syndrome with a novel missense mutation in SCN5A gene: A case report from Bangladesh

open access: yesIndian Heart Journal, 2014
Brugada syndrome is an inherited cardiac arrhythmia that follows autosomal dominant transmission and can cause sudden death. We report a case of Brugada syndrome in a 55-year-old male patient presented with recurrent palpitation, atypical chest pain and ...
Md. Zahidus Sayeed   +3 more
doaj   +1 more source

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