Results 181 to 190 of about 7,490 (233)

Bruton's tyrosine kinase inhibition for the treatment of allergic disorders. [PDF]

Ann Allergy Asthma Immunol
Lin EV, Suresh RV, Dispenza MC.
europepmc   +1 more source

小児科学 [PDF]

, 2001
二谷 武, 八木 信一, 宮脇 利男, 小西 徹, 市田 蕗子, 本郷 和久, 松倉 裕喜, 橋本 郁夫, 津幡 眞一, 足立 陽子, 足立 雄一, 野村 恵子, 金兼 弘和   +12 more
core   +1 more source

Fenebrutinib, a Bruton's tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways. [PDF]

J Neuroinflammation
Langlois J, Lange S, Ebeling M, Macnair W, Schmucki R, Li C, DeGeer J, Sudharshan TJJ, Yong VW, Shen YA, Harp C, Collin L, Keaney J.   +12 more
europepmc   +1 more source

Bruton's Tyrosine Kinase Inhibitors with Distinct Binding Modes Reveal Differential Functional Impact on B-Cell Receptor Signaling. [PDF]

Mol Cancer Ther
Li W, Sano R, Apatira M, DeAnda F, Gururaja T, Yang M, Lundgaard G, Pan C, Liu J, Zhai Y, Yoon WH, Wang L, Tse C, Souers AJ, Lee CH.   +14 more
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Expanded CD16⁺CD56⁺Granzyme B⁺ NK like CD8⁺ T cells an off target effect of bruton's tyrosine kinase inhibitors in Waldenström macroglobulinemia. [PDF]

Sci Rep
Hastak P, Phetsouphanh C, Zhang ZH, Bull RA, Shrestha LB, Klemm V, Louie R, Luciani F, Munier CML, Hoppé AC, Keoshkerian E, Beaton B, Rankin K, Wong A, Trotman J, Kelleher AD, Sasson SC.   +16 more
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Arrhythmogenic Ventricular Remodeling by Next-Generation Bruton's Tyrosine Kinase Inhibitor Acalabrutinib. [PDF]

Int J Mol Sci
Zhao Y, Chakraborty P, Tomassetti J, Subha T, Massé S, Thavendiranathan P, Billia F, Lai PFH, Abdel-Qadir H, Nanthakumar K.   +9 more
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Molecular interactions of bruton's tyrosine kinase

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Bruton’s Tyrosine Kinase in Ankylosing Spondylitis

Spine, 2023
Study Design. Prospective case-control study. Objective. To explore the role of Bruton’s tyrosine kinase (BTK) in ankylosing spondylitis (AS). Summary of Background Data.
Hsien-Tzung, Liao, Chun-Hsiung, Chen
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Signalling of Bruton's Tyrosine Kinase, Btk

Scandinavian Journal of Immunology, 1999
Bruton's tyrosine kinase, which is encoded by the BTK gene, is a cytoplasmic protein tyrosine kinase (PTK) crucial for B‐cell development and differentiation. It belongs to the Tec family of PTKs containing several domains that are characteristic of signalling molecules.
A J, Mohamed, B F, Nore, B, Christensson, C I, Smith   +3 more
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Bruton Tyrosine Kinase Degraders

American Journal of Clinical Oncology
Bruton tyrosine kinase (BTK) is a key enzyme involved in B-cell development and signaling, making it a crucial target in the treatment of B-cell malignancies, such as chronic lymphocytic leukemia and non-Hodgkin lymphoma. While BTK inhibitors (BTKi), such as ibrutinib, have been effective, resistance—both intrinsic and acquired—poses a significant ...
Giorgi, Sabakhtarishvili, Mouza, Alshebli, Omer, Bajwa, Imad A, Tabbara   +3 more
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