Results 201 to 210 of about 178,517 (322)

Inhibition of Bruton's tyrosine kinase restricts neuroinflammation following intracerebral hemorrhage. [PDF]

Theranostics
Hao H, Yin T, Li T, Zhou X, Ren H, Liu M, Huang H, Qi C, Xiu Y, Qiu W, Wang D, Shi M, Wang X, Dumont AS, Liu Q.   +14 more
europepmc   +1 more source

Bruton's tyrosine kinase is a possible therapeutic target in microscopic polyangiitis. [PDF]

Arthritis Res Ther, 2023
Nakade I, Tamura Y, Hashimoto F, Ariza Y, Hotta S, Fujigaya H, Arai S, Taniguchi M, Ogawa H, Nishibata Y, Masuda S, Nakazawa D, Tomaru U, Ishizu A.   +13 more
europepmc   +1 more source

Inhibition of Bruton's Tyrosine Kinase Suppresses Cancer Stemness and Promotes Carboplatin-induced Cytotoxicity Against Bladder Cancer Cells [PDF]

, 2020
YUEH PAN, Ya-Hsu Chiu, Shao‐Chih Chiu, Der‐Yang Cho, Liang-Ming Lee, Yu-Ching Wen, Jacqueline Whang‐Peng, Chi-Hao Hsiao, Ping‐Hsiao Shih   +8 more
openalex   +1 more source

Comparing novel treatments in chronic spontaneous urticaria: A critical appraisal of Bruton's tyrosine kinase inhibitors versus anti-cytokine biologics in clinical trials. [PDF]

Clin Transl Allergy
Diamanti A, Tontini C, Bulfone-Paus S.
europepmc   +1 more source

Mechanism of Bruton's Tyrosine Kinase-mediated Recruitment and Regulation of TFII-I

, 2004
Catarina Sacristán, Marı́a Isabel Tussié-Luna, Sheila M. Logan, Ananda L. Roy   +3 more
openalex   +1 more source

Safety, pharmacokinetics and pharmacodynamics of BI 705564, a highly selective, covalent inhibitor of Bruton's tyrosine kinase, in Phase I clinical trials in healthy volunteers [PDF]

, 2020
Tobias Litzenburger, Jürgen Steffgen, Ewald Benediktus, Fabian Müller, Armin Schultz, Elliott Klein, Meera Ramanujam, Christian Harcken, Alpana Gupta, Jing Wu, Sabrina Wiebe, Xiujiang Li, Mary Flack, Steven J. Padula, Sudha Visvanathan, Andreas Hünnemeyer, Jianan Hui   +16 more
openalex   +1 more source

Design and application of a fluorescent probe for imaging of endogenous Bruton's tyrosine kinase with preserved enzymatic activity. [PDF]

RSC Chem Biol
Valaka AP, Nyström H, Håversen L, Benitez-Martin C, Schäfer C, Jang WS, Camponeschi A, Andréasson J, Borén J, Grøtli M.   +9 more
europepmc   +1 more source

A phosphorylation site in Bruton's tyrosine kinase selectively regulates B cell calcium signaling efficiency by altering phospholipase C-γ activation

, 2004
Shuling Guo, Gregory Z. Ferl, Rajendar Deora, Mireille Riedinger, Sheng Yin, James L. Kerwin, Joseph A. Loo, Owen N. Witte   +7 more
openalex   +1 more source

The role of microglia in multiple sclerosis: implications for treatment with Bruton's tyrosine kinase inhibitors. [PDF]

Front Immunol
Vermersch P, Airas L, Berger T, Deisenhammer F, Grigoriadis N, Hartung HP, Magyari M, Popescu V, Pozzilli C, Pugliatti M, Van Wijmeersch B, Zakaria M, Oreja-Guevara C.   +12 more
europepmc   +1 more source

Rilzabrutinib, a reversible covalent Bruton's tyrosine kinase inhibitor: Absorption, metabolism, excretion, and absolute bioavailability in healthy participants. [PDF]

Clin Transl Sci, 2023
Ucpinar S, Smith PF, Long L, Li F, Yan H, Wadhwa J, Chu KA, Shu J, Nunn P, Li M.   +9 more
europepmc   +1 more source