Computational Investigation of the Covalent Inhibition Mechanism of Bruton's Tyrosine Kinase by Ibrutinib. [PDF]
Barragan AM, Ghaby K, Pond MP, Roux B.
europepmc +1 more source
E41K mutation activates Bruton's tyrosine kinase by stabilizing an inositol hexakisphosphate-dependent invisible dimer. [PDF]
Chowdhury S+5 more
europepmc +1 more source
Bruton's tyrosine kinase inhibitors in primary central nervous system lymphoma: New hopes on the horizon. [PDF]
Lino-Silva LS+2 more
europepmc +1 more source
The contribution of Bruton's tyrosine kinase to innate host defense during bacterial infections [PDF]
Liu, Z.
core +2 more sources
Screening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine Kinase. [PDF]
Kueffer LE+6 more
europepmc +1 more source
Evidence-based expert consensus on clinical management of safety of Bruton's tyrosine kinase inhibitors (2024). [PDF]
Song Z+21 more
europepmc +1 more source
The impact of Bruton's tyrosine kinase inhibitor treatment on COVID-19 outcomes in Chinese patients with chronic lymphocytic leukemia. [PDF]
Yang S+7 more
europepmc +1 more source
Labeling of Bruton's Tyrosine Kinase (BTK) Inhibitor [11C]BIO-2008846 in Three Different Positions and Measurement in NHP Using PET. [PDF]
Nag S+6 more
europepmc +1 more source
Dermatological Toxicities of Bruton’s Tyrosine Kinase Inhibitors
The development of Bruton's tyrosine kinase (BTK) inhibitors represents a major breakthrough in the treatment of chronic lymphocytic leukemia and other B cell malignancies. The first-generation inhibitor ibrutinib works by covalent irreversible binding to BTK, a non-receptor tyrosine kinase of the TEC (transient erythroblastopenia of childhood) family ...
V. Sibaud+5 more
semanticscholar +4 more sources