Results 211 to 220 of about 21,585 (263)

Immune Checkpoint Inhibitors in Cancer Therapy: Clinical Landscape, Resistance Mechanisms, and Therapeutic Innovations

MedComm – Oncology, Volume 5, Issue 3, September 2026.
The up‐to‐date clinical progress of immune checkpoint inhibitor (ICI) therapy in solid tumors, specifically the combinational regimens between ICIs and other treatment strategies, the mechanisms underlying primary and acquired resistance, and mechanism‐matched strategies to improve clinical outcomes are synthesized in this review.
Qiongyu Zhang, Zhi Qin, Caijuan Guo
wiley   +1 more source

Treatment Preferences of Patients With Myasthenia Gravis: A Qualitative Study

Muscle &Nerve, Volume 74, Issue S1, Page S124-S131, September 2026.
ABSTRACT Introduction/Aims The burden of myasthenia gravis (MG) is often underestimated, and studies usually focus on the symptom burden. However, treatment‐related adverse events also contribute to patients' burdens and affect their treatment decisions.
Meg Mendoza, Elena Wolff, Michael Chou, Vera Bril, Hans Katzberg, Ahmed Bayoumi, Carolina Barnett‐Tapia   +6 more
wiley   +1 more source

Immune resistance in hepatobiliary and pancreatic cancers: rethinking the tumor microenvironment beyond checkpoint blockade. [PDF]

Front Immunol
Xu J, Yang L, Wang S, Wu L, Liang Y, Xie X, Wang W, Gao L, Sun K, Yan J.   +9 more
europepmc   +1 more source

Development of Novel mRNA Classifiers to Stratify Preoperative Thyroid Tumor Risk

Otolaryngology–Head and Neck Surgery, Volume 175, Issue 3, Page 578-586, September 2026.
Abstract Objective Develop a preoperative risk classifier for guiding the extent of surgery in differentiated thyroid carcinomas (DTCs) under 4 cm. Study Design In silico study, validation with retrospective cohort. Setting Genomic data repositories, academic tertiary medical center.
Thomas F. Barrett, Mohamed Jama, Mohammed Alshalalfa, Theresa Tharakan, Yangyang Hao, Joshua P. Klopper, Taylor B. Cavazos, Ryan S. Jackson, Patrik Pipkorn, Jason T. Rich, Paul A. Zolkind, Douglas R. Adkins, Peter Oppelt, Anthony J. Apicelli, Nikhil Rammohan, Taylor C. Brown, Sidharth V. Puram, Sina Jasim, R. Alex Harbison   +18 more
wiley   +1 more source

Exploring and validating hub genes associated with atopic dermatitis through weighted gene co-expression network analysis and machine learning. [PDF]

Medicine (Baltimore)
Miao Y, Wang A.
europepmc   +1 more source

Structural and biophysical characterization of Mycobacterium tuberculosis DciA reveals functional convergence in DnaB helicase recognition

Protein Science, Volume 35, Issue 9, September 2026.
Abstract In bacteria, DnaB replicative helicases are essential for unwinding genomic DNA to provide the single‐stranded templates required for replication. The recruitment of the hexameric DnaB helicase to the origin of replication is mediated by distinct mechanisms that rely on specialized factors known as helicase loaders. The DciA family of helicase
Daniele Mazzoletti, Andrea Garavaglia, Hayden Fisher, Nicholas Gao, Castrese Morrone, Paul Dominic B. Olinares, Brian T. Chait, David Jeruzalmi, Riccardo Miggiano   +8 more
wiley   +1 more source

Clinical Prognostic Factors and Survival Risk Stratification for Advanced Biliary Tract Cancer Treated with Gemcitabine-Based Palliative Chemotherapy: A Real-World Retrospective Study. [PDF]

Life (Basel)
Wonglhow J, Dechaphunkul A, Sunpaweravong P, Sathitruangsak C, Wetwittayakhlang P.   +4 more
europepmc   +1 more source

Improving Gallbladder Cancer Outcomes with Antibody-Based Therapies and Immunological Profiling: A Literature Review. [PDF]

Antibodies (Basel)
Caglevic C, Contreras-Torrez MA, Reyes-Cosmelli F, Uribe-Maturana R, Mahave M, Caire N, Villanueva-Olivares L, Cid F, Lladser A, Sapunar J.   +9 more
europepmc   +1 more source

Regulating Copper Nuclearity in Metal–Organic Frameworks for the Hydrogenation of Carbon Dioxide

Small Methods, Volume 10, Issue 18, 23 September 2026.
CO2 hydrogenation on Cu‐metalated MOFs at gas–solid and liquid–solid interfaces depend strongly on the nuclearity of the Cu, which can be adjusted via the density of defects and the synthesis process. In both reaction regimes, methanol formation is favored on Cu clusters rather than on isolated Cu sites, highlighting the critical role of metal ...
Soufiane Bahou, Chanokporn Kosri, Ashour A. Ahmed, Hesham Mena, Riya Sehrawat, Sebastian Wohlrab, Thanapa Numpilai, Pongtanawat Khemthong, Thongthai Witoon, Kajornsak Faungnawakij, Bunyarat Rungtaweevoranit, Ali Abdel‐Mageed   +11 more
wiley   +1 more source

Prognosis Using Modified Albumin-Bilirubin Grade in Resected Biliary Tract Cancer: A Multicenter Propensity Score-matched Analysis. [PDF]

Cancer Diagn Progn
Takahashi T, Yanagimoto H, Akita M, Tsugawa D, Yoshida M, Ueda Y, Okazaki T, Ueno K, Miyazaki H, Otsubo I, Komatsu S, Fukumoto T.   +11 more
europepmc   +1 more source