Results 171 to 180 of about 24,552 (280)

Bruton's Tyrosine Kinase Inhibitors in Multiple Sclerosis: Mechanistic Considerations Across Relapsing and Progressive Disease. [PDF]

Molecules
Ye Q, Ma S.
europepmc   +1 more source

Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong, Jieni Li, Mingxuan Pan, Xiaoxue Ke, Hongjuan Cui   +4 more
wiley   +1 more source

„A filozófiai irodalomnak a legnehezebb könyve”

Elpis
Attila Hangai, Kosztasz Rosta
doaj   +1 more source

Clinical outcomes and feasibility of nonthermal, nontumescent ablation for isolated below-the-knee great saphenous vein incompetence. [PDF]

J Vasc Surg Venous Lymphat Disord
Min J, Park SW, Hwang JH, Kim JS, Lee SA, Hwang JJ, Chee HK, Lee YH, Yang WY, Kwon YW.   +9 more
europepmc   +1 more source

Characterization of Pectinase from Bacillus subtilis Strain Btk 27 and Its Potential Application in Removal of Mucilage from Coffee Beans [PDF]

, 2017
Oliyad Jeilu Oumer, Dawit Abate
openalex   +1 more source

A Longitudinal Spaced‐Learning Approach to Support Faculty Calibration in Periodontal Diagnosis

Journal of Dental Education, Volume 90, Issue S1, Page S82-S85, June 2026.
Clara S. Kim, Karen Matsumura‐Lem, Simon Hong, Tobias K. Boehm   +3 more
wiley   +1 more source

Breaking Barriers Between Species: Integrated Multi‐Species PK Models Improve Human PK Predictions

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT The accurate prediction of human pharmacokinetics (PK) is critical for compound selection and determining the human efficacious dose in drug discovery. Besides predicting the key PK parameters clearance (CL) and steady‐state distribution volume (Vss), the prediction of exposure metrics, e.g., maximum and trough concentrations (Cmax, Ctrough ...
Miriam S. R. Happ, Jens M. Borghardt, Charlotte Kloft, Hermann Rapp, Achim Sauer, Anneke Himstedt, Bettina Gerner   +6 more
wiley   +1 more source

Bacillus thuringiensis Sublethal Concentration Effectively Alter Cytogenetic Response of Spodoptera frugiperda Larvae. [PDF]

Neotrop Entomol
Malak M, Shonouda M.
europepmc   +1 more source

Bioinformatics analysis of BTK expression in lung adenocarcinoma: implications for immune infiltration, prognostic biomarkers, and therapeutic targeting [PDF]

Lijun Jiao, Yujian Tao, Huizhen Ding, Feng Wu, Yantong Liu, Chuang Li, Feifei Li   +6 more
openalex   +1 more source

Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults—A Pilot Study

Aging Cell, Volume 25, Issue 6, June 2026.
Can we boost vaccine responses in older adults? In a double‐blind, randomised, placebo‐controlled pilot study (n = 40, > 65 years), spermidine supplementation (6 mg/day, 13 weeks) was safe and significantly improved immune responses following a 3rd SARS‐CoV‐2 vaccine dose.
Ghada Alsaleh, Mohammad Ali, Amir Hossein Kayvanjoo, Feng Liu, Tanaïs Moreau, Sagida Bibi, Lin Luo, Melissa Govender, Miles Carroll, Sebastian J. Hofer, Eisenberg Tobias, Christoph Magnes, Loren Kell, Christopher Chung, Yu Deng, Aneesha Bhandari, Lucy Garner, Thomas Conrad, Liye Chen, Barbara Kronsteiner‐Dobramysl, Susie Dunachie, Owen B. Spiller, Teresa Lambe, Paul Klenerman, Lucy C. Jones, A. Katharina Simon   +25 more
wiley   +1 more source