Results 151 to 160 of about 78,184 (307)

First‐Line Treatment of IGHV‐Unmutated Chronic Lymphocytic Leukemia: A Network Meta‐Analysis of Targeted and Chemoimmunotherapy Regimens

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Immunoglobulin heavy chain variable region‐unmutated (IGHV‐U) chronic lymphocytic leukemia (CLL) represents a biologically aggressive subgroup with limited responsiveness to chemoimmunotherapy (CIT). To clarify the comparative effectiveness of available frontline options, we conducted a comprehensive Bayesian network meta‐analysis of ...
Santino Caserta   +13 more
wiley   +1 more source

From Time‐Limited Therapy to Treatment‐Free Observation: The Evolving Role of MRD in CLL Management

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT The integration of measurable residual disease (MRD) into the management of chronic lymphocytic leukemia (CLL) has emerged as a major advance in risk stratification and trial design, particularly in the context of time‐limited, targeted regimens.
Enrica Antonia Martino   +13 more
wiley   +1 more source

An X-ray Survey in SA 57 with XMM-Newton

open access: yes, 2007
The maximum number density of Active Galactic Nuclei (AGNs), as deduced from X-ray studies, occurs at ...
Bershady, M. A.   +5 more
core   +1 more source

Regional Standardization of CLL Management: Results of a Delphi Consensus Process

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT The therapeutic landscape of chronic lymphocytic leukemia (CLL) has been profoundly transformed by the introduction of Bruton tyrosine kinase and BCL‐2 inhibitors. Despite improved survival outcomes, treatment selection remains complex, particularly in older patients with comorbidities, frailty, and increased infectious vulnerability.
Enrica Antonia Martino   +22 more
wiley   +1 more source

Superconducting gap parameters of MgB2 obtained on MgB2/Ag and MgB2/In junctions

open access: yes, 2001
MgB2 superconducting wires with critical temperature Tc approaching 40 K were used for preparation of MgB2/Ag and MgB2/In junctions. The differential conductance vs.
A. Plecenik   +7 more
core   +1 more source

Minimal Residual Disease as a Biological Trait: Rethinking Disease Persistence in Hematologic Malignancies

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Minimal residual disease (MRD) has emerged as a central biomarker in hematologic malignancies, enabling highly sensitive detection of tumor persistence beyond conventional morphologic assessment and serving as an increasingly important surrogate endpoint in clinical trials.
Santino Caserta   +14 more
wiley   +1 more source

Selective inhibition of thromboinflammation in COVID-19 by Btk inhibitors

open access: yesPlatelets, 2020
Wolfgang Siess   +2 more
doaj   +1 more source

Pairing state in the rutheno-cuprate superconductor RuSr2GdCu2O8: A point contact Andreev Reflection Spectroscopy study

open access: yes, 2006
The results of Point Contact Andreev Reflection Spectroscopy on polycrystalline RuSr$_2$GdCu$_2$O$_8$ pellets are presented. The wide variety of the measured spectra are all explained in terms of a modified BTK model considering a \emph{d-wave ...
Bobba, Fabrizio   +5 more
core   +1 more source

Evolving treatments for Sjögren disease: current approaches and emerging targets

open access: yesInternal Medicine Journal, EarlyView.
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani   +3 more
wiley   +1 more source

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