Results 111 to 120 of about 13,307 (305)

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Heat Transfer Between Gas and Non-coalescent Liquid in a Bubble Column

Chemical Engineering Transactions, 2019
Multiphase contactors, e.g. bubble columns, are often used in operations accompanied by heat transfer between the phases. The effect of multi-orifice aerator for the heat transfer between gas and the non-coalescent liquid was investigated for two ...
Martin Zizka, Radek Sulc, Pavel Ditl
doaj   +1 more source

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

Advanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller, Nicole Vo, Utkarsh, Ivan Sokirniy, Justin Pritchard, Benjamin S. Freedman, Scott H. Medina   +6 more
wiley   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Gas Holdup and Liquid-Phase Dispersion in Packed Bubble Columns

Tikrit Journal of Engineering Sciences, 2011
The gas holdup and liquid phase axial dispersion coefficient are measured in two semi batch packed bubble columns, 10 and 15 cm diameter for an air–water system, at atmospheric conditions.
Burhan Sadeq Abdulrazzaq
doaj   +1 more source

Mixing in mechanically agitated gas-liquid contactors, bubble columns and modified bubble columns

, 1983
Mixing time measurements were made in 300 and 1000 mm i.d. mechanically agitated contactors with different types of impellers, located at different heights from the bottom of the vessel.
Joshi, J. B., A.B. Pandit, J.B. Joshi, Pandit, A. B.   +3 more
core   +1 more source

Atomic Tuning of Metal‐Support Interactions for Pathway‐Selective CO2 Photoreduction on TiO2

Advanced Science, EarlyView.
Single‐atom Fe and Cu catalysts anchored on TiO2 steer photocatalytic CO2 reduction toward distinct pathways. Fe sites favor rapid *CO desorption and selective CO formation, whereas Cu sites stabilize *CHO intermediates, enabling deep reduction and C─C coupling. Combined spectroscopy and DFT calculations reveal how metal–support interactions and oxygen
Dongyun Kim, Wonjae Ko, Byoung‐Hoon Lee, Sanghoon Kim, Yun Do Kim, Hyunsoo Ahn, Yoon Jung, Chan Woo Lee, Kug‐Seung Lee, Eunhee Gong, Junho Lee, Minho Kim, Taeghwan Hyeon, Su‐Il In   +13 more
wiley   +1 more source

Behavior of bubbles in large scale bubble column.

JOURNAL OF CHEMICAL ENGINEERING OF JAPAN, 1979
Experimental work was conducted with a 550 cm-diameter bubble column to find the influence of column diameter on circulating liquid flow, gas holdup, bubble size and bubble velocity. The relationship between average gas holdup and superficial gas velocity in the column is almost the same as that in a small-size bubble column.
KOIDE, KOZO, MOROOKA, SHIGEHARU, UEYAMA, KOREKAZU, MATSUURA, AKINORI, YAMASHITA, FUKUJI, IWAMOTO, SHINJI, KATO, YASUO, INOUE, HAKUAI, SHIGETA, MASATOMO, SUZUKI, SEIICHI, AKEHATA, TAKASHI   +10 more
openaire   +2 more sources

Simulation of the multiphase flow in bubble columns with stability-constrained multi-fluid CFD models

, 2017
The simulation of multiphase flow using multi-fluid CFD models is pertinent to the closure models for drag coefficient and bubble diameter, and empirical correlations or adjustable model parameters were inevitably needed.
Li, Jinghai, Wang, Jue, Qi Xiao, Xiao, Qi, Jinghai Li, Jue Wang, Yang, Ning, Ning Yang   +7 more
core   +1 more source

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source