Results 41 to 50 of about 4,650,576 (300)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Experimental study of bubble flow behavior during flow instability under uniform and non-uniform transverse heat distribution

Nuclear Engineering and Technology, 2020
Experiments are conducted to study bubble flow behavior during the instability of subcooled boiling under uniform and non-uniform transverse heating. The non-uniform heat distribution introduces non-uniform bubble generation and condensation rates on the
Omar S. Al-Yahia, Ho Joon Yoon, Daeseong Jo   +2 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Numerical simulation of single bubble motion fragmentation mechanism in Venturi-type bubble generator

Mechanics & Industry
Microbubbles have been widely used in power, chemical, mining and petroleum applications to improve energy efficiency. The venture-type bubble generator can improve reaction efficiency in chemical engineering as an efficient bubble generation method ...
Chen Junliang, Lei Mao, Lu Shaobo, Xiao Xiaolong, Yao Mingxiu, Li Qiang   +5 more
doaj   +1 more source

Experimental analysis of the clustering behavior of spherical bubbles rising along an inclined flat plate

Nihon Kikai Gakkai ronbunshu, 2016
The behavior of mono-dispersed spherical bubbles rising along an inclined flat plate has been observed experimentally and the effects of the inclination angle and the air flow rate have been investigated.
Toshiyuki OGASAWARA, Shota SHIRAI, Hiroyuki TAKAHIRA   +2 more
doaj   +1 more source

Numerical investigation of mass transfer behavior of a gas–liquid two‐phase Taylor flow in a microchannel by a volume‐of‐fluid multiphase flow system

International Journal of Mechanical System Dynamics, 2022
The microchannel reactor is the most commonly used microreaction technology, an innovative reaction system developed in recent years. This study investigates the mass transfer behavior of a gas–liquid two‐phase Taylor flow in a microchannel by coupling ...
Qiuwen Zhong, Zhen Jiao, Wenhui Nie, Yan Li, Ning Gu   +4 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Methods for Predicting Bubble Size Distribution in Turbulent Flow

Water Resources Research
Gas bubbles are commonly observed in both natural and human‐made water systems, and their generation and distribution play pivotal roles in water quality and aquatic habitats.
Pengcheng Li, David Z. Zhu, Hang Wang, Rongcai Tang   +3 more
doaj   +1 more source

Influence of speed on the internal flow characteristics of a multiphase pump based on a coupled CFD-PBM model

Frontiers in Physics
Under the influence of the characteristic behavior of the bubbles, the flow pattern in the multiphase pump suffers a serious deterioration and the pressurization performance is significantly reduced. In order to be more close to the engineering practice,
Xin Guo, Guangtai Shi, Hongqiang Chai, Wenjuan Lv, Jie Fu   +4 more
doaj   +1 more source

A mesoscale approach for population balance modeling of bubble size distribution in bubble column reactors

, 2017
Prediction of bubble size distribution is of paramount importance for the study of bubble column reactors. Current kernel functions for coalescence or breakage in CFD-PBM simulation are usually derived from the isotropic turbulence theory and ...
Xiao, Qi, Yang, Ning
core   +1 more source