An Optimasi Polivinil Pirolidon dan Kitosan dalam Sediaan Mucoadhesive Buccal Film Diltiazem HCl [PDF]
, 2020 Diltiazem HCl adalah golongan benzoatiazepin penghambat kanal kalsium (calcium channel blocker) yang digunakan dalam pengobatan angina pektoris, aritmia, dan hipertensi. Diltiazem HCl mengalami first pass metabolism di hati, waktu paruh yang pendek yakni
Novita, Ulfia Dwi +2 more
core +3 more sources
Formulation, characterisation and stabilisation of buccal films for paediatric drug delivery of omeprazole [PDF]
, 2015 This study aimed to develop films for potential delivery of omeprazole (OME) via the buccal mucosa of paediatric patients. Films were prepared using hydroxypropylmethylcellulose (HPMC), methylcellulose (MC), sodium alginate (SA), carrageenan (CA) and ...
A Abruzzo +27 more
core +4 more sources
Functional physico-chemical, ex vivo permeation and cell viability characterization of omeprazole loaded buccal films for pediatric drug delivery [PDF]
, 2016 Buccal films were prepared from aqueous and ethanolic Metolose gels using the solvent casting approach (40 °C). The hydration (PBS and simulated saliva), mucoadhesion, physical stability (20 °C, 40 °C), in vitro drug (omeprazole) dissolution (PBS and ...
Boateng, Joshua +2 more
core +4 more sources
Effects of cyclodextrins (β and γ) and L-Arginine on stability and functional properties of mucoadhesive Buccal Films loaded with Omeprazole for pediatric Patients [PDF]
, 2018 Omeprazole (OME) is employed for treating ulcer in children, but is unstable and exhibits first pass metabolism via the oral route. This study aimed to stabilize OME within mucoadhesive metolose (MET) films by combining cyclodextrins (CD) and l-arginine (
Armspach +5 more
core +4 more sources
Conversion of sustained release omeprazole loaded buccal films into fast dissolving strips using supercritical carbon dioxide (scCO2) processing, for potential paediatric drug delivery [PDF]
, 2016 This study involves the development of thin oral solvent cast films for the potential delivery of the proton pump inhibitor, omeprazole (OME) via the buccal mucosa for paediatric patients.
Boateng, Joshua S. +3 more
core +3 more sources
Aerosil in Solid-state Buccal Film for Improved and Sustained Delivery of Valsartan: Molecular Docking Studies [PDF]
, 2023 To overcome low oral bioavailability and short biological half-life, improved and sustained buccal delivery of valsartan has been proposed. Valsartan film with colloidal silicon dioxide has been prepared using HPMC as mucoadhesive polymer matrix by ...
Bardhan, P. +5 more
core +2 more sources
High-fidelity intensity diffraction tomography with a non-paraxial multiple-scattering model [PDF]
Opt. Express 30, 32808-32821 (2022), 2022 We propose a novel intensity diffraction tomography (IDT) reconstruction algorithm based on the split-step non-paraxial (SSNP) model for recovering the 3D refractive index (RI) distribution of multiple-scattering biological samples. High-quality IDT reconstruction requires high-angle illumination to encode both low- and high- spatial frequency ...
arxiv +1 more source
In vivo antiplasmodial potential of Carrageenan and Prosopis africana buccal films of artemether on malariogenic mice [PDF]
, 2020 Objective: To deliver bioadhesive buccal films of artemether (ART) with ability to adhere, hydrate and release drug across the buccal membrane. Methods: Buccal films prepared by film casting using carrageenan (CAR) and Prosopis africana (PRO) were ...
Attama, Anthony +9 more
core +2 more sources
OPTIMASI MORINGA GUM DAN GLISERIN DALAM SEDIAAN MUCOADHESIVE BUCCAL FILM DILTIAZEM HIDROKLORIDA [PDF]
, 2023 Moringa Gum is a gum derived from the Moringa oleifera tree which can be used as a stabilizer, binder, mucoadhesive, disintegrant, sustained release and controlled release matrix.
Lidya Ameliana +2 more
core +2 more sources
BUCCAL FILM: A NOVEL APPROACH FOR ORAL MUCOSAL DRUG DELIVERY SYSTEM [PDF]
, 2021 Buccal drug delivery especially refers to the delivery of drugs through the buccal mucosal membrane lining of the oral cavity. For geriatric and pediatric patients who undergo difficulties in swallowing conventional oral solid dosage forms, the buccal ...
BAIG, REESHA +3 more
core +1 more source