Cubic Microcontainers Improve In Situ Colonic Mucoadhesion and Absorption of Amoxicillin in Rats [PDF]
Pharmaceutics, 2020 An increased interest in colonic drug delivery has led to a higher focus on the design of delivery devices targeting this part of the gastrointestinal tract. Microcontainers have previously facilitated an increase in oral bioavailability of drugs.
Antonio José Guillot +2 more
exaly +4 more sources
Development of keratin nanoparticles for controlled gastric mucoadhesion and drug release
Journal of Nanobiotechnology, 2018 Background Nanotechnology-based drug delivery systems have been widely used for oral and systemic dosage forms delivery depending on the mucoadhesive interaction, and keratin has been applied for biomedical applications and drug delivery.
Zhongjun Cheng +8 more
doaj +2 more sources
Recent advancement in polymeric nanoparticles for oral chemotherapy: Transforming cancer treatment [PDF]
BioImpactsOral chemotherapy offers an attractive alternative to conventional intravenous administration by providing high patient compliance and improved treatment adherence.
Karthik Mangu +2 more
doaj +2 more sources
Heliyon, 2023 The present work aimed to develop nanoparticles of tobramycin (TRM) using thiolated chitosan (TCS) in order to improve the mucoadhesion, antibacterial effect and pharmacokinetics.
Sadaf Javed +14 more
doaj +1 more source
Development of nanoparticles coated with cassava bagasse pectin (Manihot esculenta Crantz) containing β-carotene for mucoadhesive applications [PDF]
Anais da Academia Brasileira de Ciências, 2020 Pectin (PC) extracted from a solid residue from cassava roots (Manihot esculenta Crantz) was used to coat nanoparticles (NP) containing β-carotene (BC) aiming at the gastrointestinal administration of this lipophilic nutraceutical.
BIANCA COELHO +9 more
doaj +1 more source
Study on Mucoadhesion Properties of Chitosan [PDF]
علوم و تکنولوژی پلیمر, 2008 Using controlled drug delivery devices is one of the novel methods of drug delivery which is used to perform drug therapy with the minimum side effects. Mucoadhesive polymers are one of these devices.
S.M. Taghizadeh, G. Davari
doaj +1 more source
Foods, 2021 Whey protein is fortified into beverages to provide functional benefits, however, these beverages are considered mouthdrying. To date whey protein derived mouthdrying has not been quantified using a ‘physical measure’ in parallel with rated perception ...
Victoria Norton +2 more
doaj +1 more source
Pharmacokinetic Investigation to Study the In Vivo Bioavailability of Thiolated Chitosan Based Repaglinide Buccal Tablets [PDF]
Pharmaceutical Sciences, 2020 Background: Repaglinide (REP) is an antihyperglycemic drug having low bioavailability due to its extensive first-pass metabolism. The present study aimed to develop and pharmacokinetic investigte the thiolated chitosan (TC) based buccal tablets of REP ...
Raja Navamanisubramanian +2 more
doaj +1 more source
Polycomplex Carrier for Buccal Mucoadhesion Delivery of Metronidazole
Разработка и регистрация лекарственных средств, 2020 Introduction. One of the well-known requirements for buccal drug delivery systems is the demonstration of mucoadhesive properties of the carrier, ensuring retention on the mucosa for a long time with the gradual release of the included drug. It should be
R. I. Moustafine +4 more
doaj +1 more source
Comparative Evaluation of Polymers for Fabrication of Mucoadhesive Tablets: Impact on Mucoadhesion Properties and In-vitro Drug Release [PDF]
Brazilian Journal of Pharmaceutical SciencesThis study explores the effect of various polymers on drug release and mucoadhesion, using miconazole as a model drug. Tablets were prepared with polymers such as Eudragit RS, hydroxypropyl methylcellulose (HPMC), carbomer 940, cress seed gum (CSG ...
Sadaf Eshraghi +3 more
doaj +2 more sources