Results 31 to 40 of about 7,134 (210)

Mucoadhesive Gelatin Buccal Films with Propranolol Hydrochloride: Evaluation of Mechanical, Mucoadhesive, and Biopharmaceutical Properties [PDF]

Pharmaceutics, 2021
This study processes and characterizes propranolol hydrochloride/gelatin mucoadhesive buccal films. Two types of gelatin are used: Gelatin from porcine skin, type A (GA), and gelatin from bovine skin (GB). The influence of gelatin type on mechanical, mucoadhesive, and biopharmaceutical characteristics of buccal films is evaluated.
Marija Jovanović, Nataša Tomić, Sandra Cvijić, Dušica Stojanović, Svetlana Ibrić, Petar Uskoković   +5 more
openaire   +6 more sources

Development and evaluation of aceclofenac-loaded mucoadhesive microcapsules

Journal of Advanced Pharmaceutical Technology & Research, 2011
Microencapsulation is an accepted process used to achieve controlled release and drug targeting for many years. Mucoadhesion has been a topic of interest in the design of drug delivery systems to prolong its intestinal residence time.
Santhosh Kumar Mankala, Appanna Chowdary Korla, Sammaiah Gade   +2 more
doaj   +1 more source

Development of a Standardized Method for Measuring Bioadhesion and Mucoadhesion That Is Applicable to Various Pharmaceutical Dosage Forms

Pharmaceutics, 2022
Although some methods for measuring bioadhesion/mucoadhesion have been proposed, a standardized method is not yet available. This is expected to hinder systematic comparisons of results across studies.
Lola Amorós-Galicia, Anna Nardi-Ricart, Clara Verdugo-González, Carmen Martina Arroyo-García, Encarna García-Montoya, Pilar Pérez-Lozano, Josep Mª Suñé-Negre, Marc Suñé-Pou   +7 more
doaj   +1 more source

Improved Mucoadhesion, Permeation and In Vitro Anticancer Potential of Synthesized Thiolated Acacia and Karaya Gum Combination: A Systematic Study

Molecules, 2022
Thiolation of polymers is one of the most appropriate approaches to impart higher mechanical strength and mucoadhesion. Thiol modification of gum karaya and gum acacia was carried out by esterification with 80% thioglycolic acid.
Neha Munot, Ujjwala Kandekar, Chaitali Rikame, Abhinandan Patil, Poulomi Sengupta, Shabana Urooj, Anusha Bilal   +6 more
doaj   +1 more source

Formulation and evaluation of controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum

Journal of Advanced Pharmaceutical Technology & Research, 2011
The aim of study was to prepare controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum as natural polymer. Tablets were formulated by direct compression technology employing the natural polymer in different concentrations
Gurpreet Arora, Karan Malik, Inderbir Singh, Sandeep Arora, Vikas Rana   +4 more
doaj   +1 more source

Development of Thermosensitive and Mucoadhesive Hydrogel for Buccal Delivery of (S)-Ketamine

Pharmaceutics, 2022
(S)-ketamine presents potential for the management of acute pain and, more specifically, for the prevention of pain associated with care. However, the administration route can be a source of pain and distress.
Agathe Thouvenin, Balthazar Toussaint, Jelena Marinovic, Anne-Laure Gilles, Amélie Dufaÿ Wojcicki, Vincent Boudy   +5 more
doaj   +1 more source

Buccal Thin Films as Potent Permeation Enhancers for Cytisine Transbuccal Delivery

Membranes, 2022
Cytisine (CYT) is a powerful anti-smoking compound which could greatly benefit from transbuccal delivery because of both its unfavorable pharmacokinetics after oral administration and its intrinsic ability to permeate the buccal mucosa. This work aims to
Viviana De Caro, Giuseppe Angellotti, Fabio D’Agostino, Giulia Di Prima   +3 more
doaj   +1 more source

Development of Eudragit^® Nanoparticles for Intranasal Drug Delivery: Preliminary Technological and Toxicological Evaluation

Applied Sciences, 2022
Intranasal administration has assumed in the last years an increasing value as an alternative strategy for the systemic adsorption of drugs, as an alternative to oral and parenteral routes thanks to the high vascularized nasal mucosa.
Roberta Corsaro, Rosamaria Lombardo, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Daniele Bani, Angela Bonaccorso, Rosario Pignatello   +6 more
doaj   +1 more source

Assessing Mucoadhesion in Polymer Gels: The Effect of Method Type and Instrument Variables [PDF]

, 2018
The process of mucoadhesion has been widely studied using a wide variety of methods, which are influenced by instrumental variables and experiment design, making the comparison between the results of different studies difficult.
Cook, Michael Thomas, Marcos Bruschi, Jéssica Bassi da Silva, Sabrina Ferreira, Michael Cook, da Silva, Jéssica Bassi, Reis, Adriano Valim, Bruschi, Marcos Luciano, Adriano Reis, Ferreira, Sabrina Barbosa de Souza   +9 more
core   +1 more source

Comparison of in vitro methods of measuring mucoadhesion: Ellipsometry, tensile strength and rheological measurements

, 2012
In this work three in vitro methods for the measurement of mucoadhesion have been compared: ellipsometry, tensile strength and rheology. The conditions used for the three methods have been as similar as possible. Six different polymers were investigated:
Lund University., Ivarsson, David, Wahlgren, Marie,   +2 more
core   +2 more sources