Results 21 to 30 of about 7,134 (210)

Bilayer Mucoadhesive Buccal Film for Mucosal Ulcers Treatment: Development, Characterization, and Single Study Case

Pharmaceutics, 2020
The formation of mucosal ulcers is an end result of epithelial damage, and it occurs due to some specific causes, such as trauma, aphthous stomatitis, lichen planus and lichenoid reactions, cytotoxic effects of chemotherapy and radiation, and drug ...
Thais F. R. Alves, Alesssandra C. Rios, Katiusca da Silva Pontes, Decio L. Portella, Norberto Aranha, Patricia Severino, Eliana B. Souto, Joyce K. M. Gonsalves, Rogeria de Souza Nunes, Marco V. Chaud   +9 more
doaj   +1 more source

Preparation and evaluation of Levosalbutamol sulphate chitosan microsphere for the treatment of asthma

Journal of Pharmacy and Bioallied Sciences, 2012
Mucoadhesive drug delivery systems are those that provide intimate contact of the drug with the mucosa for an extended period of time. In present work, mucoadhesive chitosan microspheres of Levosalbutamol sulphate were prepared by Spray drying method ...
D Dinal Patel, V Nirav Patel, T Vaishali Thakkar, R Tejal Gandhi   +3 more
doaj   +1 more source

In Vitro and In Vivo Evaluation of a Nano-Tool Appended Oil_mix (Clove and Tea Tree Oil) Thermosensitive Gel for Vaginal Candidiasis

Journal of Functional Biomaterials, 2022
The main objective of the proposed work was the development of a thermosensitive gel (containing clove and tea tree oil) for the management of vaginal candidiasis. Both oils have been recommended to be used separately in a topical formulation for vaginal
Abdulrab Ahmed M. Alkhanjaf, Md Tanwir Athar, Zabih Ullah, Ahmad Umar, Ibrahim Ahmed Shaikh   +4 more
doaj   +1 more source

Mucoadhesive Nanocarriers as a Promising Strategy to Enhance Intracellular Delivery against Oral Cavity Carcinoma

Pharmaceutics, 2022
Oral cancer, particularly squamous cell carcinoma (SCC), has posed a grave challenge to global health due to its high incidence, metastasis, and mortality rates.
Manisha Pandey, Hira Choudhury, Jenifer Ngu Shao Ying, Jessica Foo Sze Ling, Jong Ting, Jocelyn Su Szhiou Ting, Ivory Kuek Zhia Hwen, Ho Wan Suen, Hazimah Syazwani Samsul Kamar, Bapi Gorain, Neha Jain, Mohd Cairul Iqbal Mohd Amin   +11 more
doaj   +1 more source

Augmentation of Antidiabetic Activity of Glibenclamide Microspheres Using S-Protected Okra Powered by QbD: Scintigraphy and In Vivo Studies

Pharmaceuticals, 2022
Successful drug delivery by mucoadhesive systems depends on the polymer type, which usually gets adherent on hydration. The intended polymers must sustain the association with biomembranes and preserve or accommodate the drug for an extended time.
Waleed Y. Rizg, N. Raghavendra Naveen, Mallesh Kurakula, Awaji Y. Safhi, Samar S. Murshid, Rayan Y. Mushtaq, Walaa A. Abualsunun, Majed Alharbi, Rana B. Bakhaidar, Alshaimaa M. Almehmady, Ahmad Salawi, Adel Al Fatease, Khaled M. Hosny   +12 more
doaj   +1 more source

Development of an ANN optimized mucoadhesive buccal tablet containing flurbiprofen and lidocaine for dental pain

Acta Pharmaceutica, 2016
A novel mucoadhesive buccal tablet containing flurbiprofen (FLB) and lidocaine HCl (LID) was prepared to relieve dental pain. Tablet formulations (F1-F9) were prepared using variable quantities of mucoadhesive agents, hydroxypropyl methyl cellulose (HPMC)
Hussain Amjad, Syed Muhammad Ali, Abbas Nasir, Hanif Sana, Arshad Muhammad Sohail, Bukhari Nadeem Irfan, Hussain Khalid, Akhlaq Muhammad, Ahmad Zeeshan   +8 more
doaj   +1 more source

Novel Mucoadhesive Wafers for Treating Local Vaginal Infections

Biomedicines, 2022
Current vaginal formulations, such as gels and pessaries, have limitations, including poor retention. Therefore, the use of mucoadhesive formulations that adhere to the vaginal wall would allow prolonged retention and controlled drug release while ...
Ahmed Alzainy, Joshua Boateng
doaj   +1 more source

Lactobacillus crispatus BC1 Biosurfactant Delivered by Hyalurosomes: An Advanced Strategy to Counteract Candida Biofilm

Antibiotics, 2021
The emergence of resistance to antifungal drugs has made the treatment of vulvovaginal candidiasis (VVC) very challenging. Among natural substances, biosurfactants (BS) produced by Lactobacillus have gained increasing interest in counteracting Candida ...
Angela Abruzzo, Barbara Giordani, Carola Parolin, Priscilla R. De Gregorio, Claudio Foschi, Teresa Cerchiara, Federica Bigucci, Beatrice Vitali, Barbara Luppi   +8 more
doaj   +1 more source

Sorafenib Repurposing for Ophthalmic Delivery by Lipid Nanoparticles: A Preliminary Study

Pharmaceutics, 2021
Uveal melanoma is the second most common melanoma and the most common intraocular malignant tumour of the eye. Among various treatments currently studied, Sorafenib was also proposed as a promising drug, often administered with other compounds in order ...
Angela Bonaccorso, Veronica Pepe, Cristina Zappulla, Cinzia Cimino, Angelo Pricoco, Giovanni Puglisi, Francesco Giuliano, Rosario Pignatello, Claudia Carbone   +8 more
doaj   +1 more source

Posterior Segment Ophthalmic Drug Delivery: Role of Muco-Adhesion with a Special Focus on Chitosan

Pharmaceutics, 2021
Posterior segment eye diseases (PSEDs) including age macular degeneration (AMD) and diabetic retinopathy (DR) are amongst the major causes of irreversible blindness worldwide.
Ayah Mohammad Burhan, Butsabarat Klahan, Wayne Cummins, Vanessa Andrés-Guerrero, Mark E. Byrne, Niall J. O’Reilly, Anuj Chauhan, Laurence Fitzhenry, Helen Hughes   +8 more
doaj   +1 more source