Results 11 to 20 of about 7,134 (210)

Mucoadhesion: A food perspective [PDF]

Food Hydrocolloids, 2017
The role of mucoadhesion in the perception and sensory characterisation of food products is becoming more apparent. Traditionally, mucoadhesives are used to enhance drug permeability and retention at mucosal membranes in the body, by adherence to a mucosal membrane formed through various interactions between the mucoadhesive and proteins present in the
Sarah L. Cook, Stephanie P. Bull, Lisa Methven, Jane K. Parker, Vitaliy V. Khutoryanskiy   +4 more
openaire   +2 more sources

Advances in Mucoadhesion and Mucoadhesive Polymers

Macromolecular Bioscience, 2010
AbstractMucoadhesion is the ability of materials to adhere to mucosal membranes in the human body and provide a temporary retention. This property has been widely used to develop polymeric dosage forms for buccal, oral, nasal, ocular and vaginal drug delivery.
Khutoryanskiy, Vitaliy V., Vitaliy V. Khutoryanskiy   +1 more
openaire   +3 more sources

Mucoadhesive drug delivery systems

Journal of Pharmacy and Bioallied Sciences, 2011
Mucoadhesion is commonly defined as the adhesion between two materials, at least one of which is a mucosal surface. Over the past few decades, mucosal drug delivery has received a great deal of attention.
Rahamatullah Shaikh, Thakur Raghu Raj Singh, Martin James Garland, A David Woolfson, Ryan F Donnelly   +4 more
doaj   +4 more sources

Breaking Physiological Barriers in Women's Health: Mucoadhesive and Stimuli-Responsive Nanomaterials. [PDF]

Wiley Interdiscip Rev Nanomed Nanobiotechnol
Drug delivery vehicles generated from biomaterials for women's health. In particular, the breast and the reproductive system, including the ovary, uterus, cervix, vagina, and the surrounding tissues, targeted drug delivery. BioRender. ABSTRACT Biomaterials are natural or synthetic molecules that exhibit biocompatibility, biodegradability, or ...
Parsons M, Parker AR, Schneider L, Sullivan T, Givens BE.   +4 more
europepmc   +2 more sources

Applications of chitosan derivatives as adjuvants for nanoparticle-based vaccines: A comprehensive review. [PDF]

Smart Mol
This review highlights how chitosan derivatives enhance nanoparticle‐based vaccines through superior stability, mucoadhesion, and immune modulation. By triggering robust mucosal, humoral, and cellular responses, these biocompatible polymers serve as a transformative platform for next‐generation immunotherapeutics and safe and effective vaccine delivery
Dasgupta S, Paul S, Mukherjee S, Sarkar N, Kumar A, Chakraborty A, Bose A, Hazra A, Chakraborty M.   +8 more
europepmc   +2 more sources

Mucoadhesive Peptide-Catalase Self-Assembled Nano-Formulation for Effective Treatment of Mucosal Inflammatory Diseases. [PDF]

Adv Sci (Weinh)
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Li X, Ma Y, He D, Huang Y, Jiang Y, Zhao H, Ge S, Zhao R, Yuan H, Jiang W, Zhu W, Liu K, Zhang H, Liu Z.   +13 more
europepmc   +2 more sources

Mucoadhesion : mucin-polymer molecular interactions

, 2021
Mucoadhesion, adhesion of a material to a mucous membrane or a mucus-covered surface, has been employed in drug delivery to prolong contact with adsorption sites and consequently a likely improvement of drug absorption.
Topgaard, Daniel, Edman, Martin, Lindell, Katarina, Nöjd, Sofi, Pham, Quoc Dat, Wahlgren, Marie   +5 more
core   +2 more sources

Mucoadhesive Marine Polysaccharides

Marine Drugs, 2022
Mucoadhesive polymers are of growing interest in the field of drug delivery due to their ability to interact with the body’s mucosa and increase the effectiveness of the drug. Excellent mucoadhesive performance is typically observed for polymers possessing charged groups or non-ionic functional groups capable of forming hydrogen bonds and electrostatic
Irina M. Yermak, Viktoriya N. Davydova, Aleksandra V. Volod’ko   +2 more
openaire   +3 more sources

Mucoadhesion of Progesterone-Loaded Drug Delivery Nanofiber Constructs [PDF]

, 2018
Mucoadhesive delivery systems have attracted remarkable interest recently, especially for their potential to prolong dosage form resident times at sites of application such as the vagina or nasal cavity, thereby improving convenience and compliance as a ...
Mahalingam, Suntharavathanan, Thorogate, R, Bahijja Raimi-Abraham, Suntharavathanan Mahalingam, Raimi-Abraham, Bahijja, Raimi-Abraham, B, Edirisinghe, Mohan, Duncan Q. M. Craig, Brako, F, Craig, DQM, Craig, Duncan Q.M., Edirisinghe, M, Richard Thorogate, Mohan Edirisinghe, Mahalingam, S, Thorogate, Richard, Brako, Francis, Francis Brako   +17 more
core   +2 more sources

Aldehyde-functional thermoresponsive diblock copolymer worm gels exhibit strong mucoadhesion [PDF]

, 2022
A series of thermoresponsive diblock copolymer worm gels is prepared via reversible addition–fragmentation chain transfer (RAFT) aqueous dispersion polymerization of 2-hydroxypropyl methacrylate using a water-soluble methacrylic precursor bearing pendent
Armes, Steven P., Smallridge, Mark J., Khutoryanskiy, Vitaliy V., Neal, T.J., Neal, Thomas J., Brotherton, E.E., Smallridge, M.J., Khutoryanskiy, V.V., Brotherton, Emma E., Kaldybekov, Daulet B., Armes, S.P., Kaldybekov, D.B.   +11 more
core   +1 more source