Results 51 to 60 of about 7,134 (210)
Food Safety and Health, EarlyView.In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso +3 more
wiley +1 more source
Drug DeliveryWith the rapid development of buccal films (BFs), the demand for film-forming materials and preparation techniques has increased. Cellulose ethers (CEs) exhibit favorable properties, such as effective film formation, mucosal adhesion, and ...
Hong Cheng +5 more
doaj +1 more source
Drug Design, Development and Therapy, 2021 Tivadar Bíró,1 Alexandra Bocsik,2 Bisera Jurišić Dukovski,3 Ilona Gróf,2,4 Jasmina Lovrić,3 Ildikó Csóka,1 Mária A Deli,2 Zoltán Aigner1 1Institute of Pharmaceutical Technology and Regulatory ...
Bíró T +7 more
doaj
Journal of Indian Academy of Oral Medicine and Radiology, 2016 Aims and Objectives: To evaluate and compare the efficacy of diclofenac and meloxicam as mucoadhesive patches in dental pain management. Materials and Method: This study was conducted among 45 adult patients of either sex, who were diagnosed with dental ...
Pratik R Pipalia +3 more
doaj +1 more source
Responsive Materials, EarlyView.Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan +8 more
wiley +1 more source
Mucosa-mimetic materials to replace animal tissue in mucoadhesion research
, 2016 Pharmaceutical scientists often wish to design dosage forms which adhere to mucosal membranes to provide a localised effect. These “mucoadhesive” formulations are typically evaluated using ex vivo animal tissue, a large amount of which is sourced from ...
Cook, Michael
core +4 more sources
Small, EarlyView.Schematic representation of diffusion‐based versus pH‐triggered drug release within a bacterial biofilm. In diffusion‐based systems, drug cargo is gradually released independent of local pH, resulting in rapid burst release and reduced sustained concentrations.
Amalie Kjær Andresen +9 more
wiley +1 more source
Binding and mucoadhesion of sulfurated derivatives of quaternary ammonium-chitosans and their nanoaggregates: An NMR investigation [PDF]
, 2020 The effect of insertion of SH and S-protected groups on the binding and mucoadhesion properties of quaternary ammonium-chitosans and their nanoparticulate forms has been investigated by NMR spectroscopy.
Fabiano A. +5 more
core +1 more source
GelsThe objective of this work was to investigate the use of nanocrystalline cellulose (NCC) as a drug-delivery excipient for buccal films. Gel-like dispersions were created by blending either gel or powder NCC (gNCC or pNCC) with natural polymers (alginate,
Katarina Bolko Seljak +3 more
doaj +1 more source
Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus
Advanced Science, Volume 13, Issue 55, 5 October 2026.Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto +5 more
wiley +1 more source