Results 151 to 160 of about 2,290,590 (298)

Nicotine stabilization in composite sodium alginate based wafers and films for nicotine replacement therapy [PDF]

, 2017
Composite wafers and films comprising HPMC and sodium alginate (SA) were formulated for nicotine (NIC) replacement therapy via the buccal route. Magnesium aluminium silicate (MAS) was added in different concentration ratios (0.25, 0.5, 0.75) to stabilize
Adhikari, Adrian, Aguzzi, Benowitz, Boateng, Boateng, Boateng, Dash, Gilman, Joshua S. Boateng, Khan, Manivannan, Mihranyan, Morales, Nair, Nair, Obinna C. Okeke, Okeke, Pandey, Pavlidou, Pawar, Pongjanyakul, Pongjanyakul, Pongjanyakul, Prabaharan, RakiĿ, Rowe, Sattar, Shoaib, Siepmann, Singhvi, Smart, ÿkinci   +32 more
core   +1 more source

Design, development, and optimization of mucoadhesive buccal films of ganaxolone for enhanced bioavailability

Journal of Applied Pharmaceutical Research
Background: CDD disorder affects children mainly during their first three months of life. The buccal route offers advantages over oral administration for ganaxolone by avoiding first-pass metabolism and providing direct systemic absorption.
Onkar Pawar, Rahul Godge, Ganesh Shinde, Kailas Barde, Akshay Vikhe   +4 more
doaj   +1 more source

Mucoadhesive Drug Delivery Systems for Oral Chronic Inflammatory Mucosal Diseases. The Future is Already Present. A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Background Oral lichen planus (OLP) and recurrent aphthous stomatitis (RAS) are considered the most painful oral inflammatory diseases, with high global prevalence and significant impacts on patients' quality of life. In the last decades, researchers have been exploring mucoadhesive drug delivery systems (MDDS) to improve drugs safety and ...
M. E. Mauceri, M. Coppini, V. De Caro, G. Di Prima, R. Mauceri, V. Panzarella, G. Giuliana, G. Campisi   +7 more
wiley   +1 more source

Acellular Bi-Layer Silk Fibroin Scaffolds Support Tissue Regeneration in a Rabbit Model of Onlay Urethroplasty [PDF]

, 2014
Acellular scaffolds derived from Bombyx mori silk fibroin were investigated for their ability to support functional tissue regeneration in a rabbit model of urethra repair.
Adam, Rosalyn M., Algarrahi, Khalid, Chung, Yeun Goo, Estrada Jr., Carlos R., Franck, Debra, Gil, Eun Seok, Kaplan, David L., Mauney, Joshua R., Tu, Duong   +8 more
core   +2 more sources

Development and Characterization of Buccal Film of Candesartan

Pharmaceutical Methods, 2016
Candesartan is potent antihypertensive drug of class angiotensin II receptor antagonist. But it exhibits poor water solubility and extensive first pass metabolism. Present research deals with development of candesartan buccal film. Optimisation of buccal film was done by design expert.
Malpure, Dipak Rajaram, Deore, Sharada Laxman   +1 more
openaire   +1 more source

The oral microbiota and periodontal health in orthodontic patients

Periodontology 2000, EarlyView.
Abstract The oral microbiota develops within the first 2 years of childhood and becomes distinct from the parents by 4 years‐of‐age. The oral microbiota plays an important role in the overall health/symbiosis of the individual. Deviations from the state of symbiosis leads to dysbiosis and an increased risk of pathogenicity.
Brandon W. Peterson, Geerten‐Has Tjakkes, Anne‐Marie Renkema, David J. Manton, Yijin Ren   +4 more
wiley   +1 more source

3D printed mucoadhesive gelatin based buccal films

, 2021
The oral mucoadhesive film is a novel and attractive formulation for local and/or systemic drug delivery through the mucosal membrane of the oral cavity. Certain active pharmaceutical ingredients (API) in conventional formulations (tablets, capsules, syrups) are absorbed in the gastrointestinal tract and undergo first-pass metabolism through the liver,
Jovanović, Marija N., Radisavljević, Anđela N., Petrović, Miloš M., Stojanović, Dušica B., Ibrić, Svetlana R., Uskoković, Petar S.   +5 more
openaire   +1 more source

Periodontal and orthodontic management of impacted canines

Periodontology 2000, EarlyView.
Abstract The maxillary and mandibular canines are described by many clinicians as the “cornerstone” of the arch. When in their optimal position, they play a critical role in providing a well‐balanced occlusal scheme that contributes toward functional as well as neuromuscular stability, harmony, esthetics, and dentofacial balance.
Mohammad Qali, Chenshuang Li, Chun‐Hsi Chung, Nipul Tanna   +3 more
wiley   +1 more source

Three‐dimensional digital quantitative analysis of periodontal and peri‐implant phenotype—A narrative review

Periodontology 2000, EarlyView.
Abstract 3D digital evaluation of the periodontal and peri‐implant tissue, including CBCT, intraoral scanning, optical surface scanning, and ultrasonography, is being used in the clinical arena with increasing frequency. Thus, to validate the utilization of 3D digital analysis for this purpose, a critical evaluation of the reliability of digital ...
Yi Te Lin, Chenshuang Li, Jonathan Korostoff, Joseph P. Fiorellini, Jie Yang, Yu‐Cheng Chang   +5 more
wiley   +1 more source

Formulation and evaluation of a bioadhesive patch for buccal delivery of tizanidine

Acta Pharmaceutica Sinica B, 2012
Tizanidine hydrochloride (THCl) is an antispasmodic agent which undergoes extensive first pass metabolism making it a possible candidate for buccal delivery.
Mohamed S. Pendekal, Pramod K. Tegginamat   +1 more
doaj   +1 more source