Results 251 to 260 of about 2,290,590 (298)

Buccal Mucoadhesive Films: A Review

Systematic Reviews in Pharmacy, 2016
Traditional oral dosage forms prone to first pass metabolism and degra-dation due to enzymes but mucoadhesive films able to bypass first pass metabolism and related degradation. It also offers more patient compliance without risk of chocking in case of paediatric and geriatric patients. Present review has summarised basics of mucoadhesion, composition,
Dipak Malpure Rajaram, Sharada Deore Laxman   +1 more
openaire   +1 more source

In vitro techniques to evaluate buccal films

Journal of Controlled Release, 2013
Extensive research on transmucosal drug delivery in the past few decades has resulted in the clinical application of several drug molecules through the buccal route. Interestingly, most of the new chemical moieties under clinical trials are being screened for their potential to deliver through the buccal cavity.
Anroop B, Nair, Rachna, Kumria, Sree, Harsha, Mahesh, Attimarad, Bandar E, Al-Dhubiab, Ibrahim A, Alhaider   +5 more
openaire   +2 more sources

Manufacture and characterization of mucoadhesive buccal films

European Journal of Pharmaceutics and Biopharmaceutics, 2011
The buccal route of administration has a number of advantages including bypassing the gastrointestinal tract and the hepatic first pass effect. Mucoadhesive films are retentive dosage forms and release drug directly into a biological substrate. Furthermore, films have improved patient compliance due to their small size and reduced thickness, compared ...
Javier O, Morales, Jason T, McConville
openaire   +2 more sources

Formulation And Evaluation Of Buccal Film Of Vortioxetine Hydrobromide

International Journal of Research Publication and Reviews
: Vortioxetine hydrobromide is an atypical antidepressant used in the treatment of major depressive disorder (MDD). However, its oral bioavailability is limited due to poor solubility and first-pass metabolism.
Shubham M. Gadekar, Pranjal P. Lohakane, D. Salve   +2 more
semanticscholar   +1 more source

Mechanical strength test for orodispersible and buccal films

International Journal of Pharmaceutics, 2014
There are no test procedures, definitions and specifications available how to determine mechanical strength of orodispersible or buccal films. Aim of the study was to develop an appropriate and discriminating method to feature the evaluation of marketed and newly developed film products covering well-known and new approaches.
Maren Preis, Klaus Knop, Jörg Breitkreutz   +2 more
openaire   +2 more sources

Innovative buccal film delivery system for hypertension: Combining candesartan and hydrochlorothiazide

Journal of Biomaterials Applications
This study explores the development of buccal films as an innovative drug delivery system for hypertension management, combining candesartan cilexetil (CC) and hydrochlorothiazide (HCTZ).
Ola Tarawneh, Aisha Kanan, W. Al-Zyoud, Mohammad Khanfar, Mohammad Hailat, Ala A. Alhusban, Razan Abu Jaber   +6 more
semanticscholar   +1 more source

Incorporation of Antihypertensive Class IV Drug in Novel Buccal Film Formulation

Asian Journal of Pharmaceutical Research
Chlorthalidone is a thiazide-like diuretic drug used in the treatment of hypertension. It belongs to class IV of Biopharmaceutical Classification System (BCS) and exhibits first pass metabolism leading to low bioavailability.
Adesh Yelave, Geeta Sameer Bhagwat, Adnan Rehmatullah Siddique   +2 more
semanticscholar   +1 more source

Significance and Advantages of Buccal Film for Diabetes Management: Biocompatibility and Safety Considerations

International journal of pharmaceutical research and applications
Buccal film technology has emerged as a promising approach for diabetes management due to its unique advantages over conventional dosage forms. This review paper explores the significance of buccal films in diabetes management, highlighting their ...
Mr. Surya Prakash, Mr. Pravin Kumar Sahu, Ms. Geetanjali Sahu   +2 more
semanticscholar   +1 more source

Exploring the Role of Buccal Film in Drug Delivery

Asian Journal of Pharmacy and Technology
A buccal film is a thin film of medication placed between the gum and cheek and left to dissolve. It is commonly used as a method of drug delivery, particularly for medications that need to be administered in small doses over a long period of time.
V. Harshitha, P. Swetha, G. Bhuvaneshwari, N. Sreelatha, V. Ramya, Y. Kalyan   +5 more
semanticscholar   +1 more source

Nanosuspension-Based Repaglinide Fast-Dissolving Buccal Film for Dissolution Enhancement

AAPS PharmSciTech
Drug solubility and dissolution remain a significant challenge in pharmaceutical formulations. This study aimed to formulate and evaluate repanglinide (RPG) nanosuspension-based buccal fast-dissolving films (BDFs) for dissolution enhancement.
Hamsa Yaseen Ghadhban, K. K. Ahmed
semanticscholar   +1 more source