Results 31 to 40 of about 2,290,590 (298)
Study of the Effect of Temperature on the Production of Carrageenan-Based Buccal Films and Optimization of the Process Parameters [PDF]
PharmaceuticalsBackground/Objectives: Films in the mouth offer a promising alternative drug delivery system for oral administration, with several advantages over traditional oral formulations.
Katalin Kristó +6 more
doaj +2 more sources
International Journal of Current Pharmaceutical Research, 2021 The buccal route of administration has many advantages, including gastrointestinal bypass surgery and first pass through the liver. The mucoadhesive membrane is a retention dosage form that can release the drug directly into the biological matrix. Cheek technology has proven to be an advanced alternative to other traditional devices.
SINDHU G. D. +2 more
openaire +2 more sources
Buprenorphine Buccal Film for Chronic Pain Management [PDF]
Pain Management, 2020 Buprenorphine is a Schedule III opioid with unique pharmacodynamic and pharmacokinetic properties that contribute to effective analgesia and fewer safety risks than other opioids. This review article focuses on the buccal film formulation, which is preferable to other buprenorphine formulations on the basis of bioavailability, safety and efficacy.
Martin, Hale +2 more
openaire +2 more sources
An Updated Overview of the Emerging Role of Patch and Film-Based Buccal Delivery Systems
Pharmaceutics, 2021 Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery, anatomical and physiological aspects of oral mucosa, and various in ...
Shery Jacob +5 more
doaj +1 more source
Buccal films of prednisolone with enhanced bioavailability [PDF]
Drug Delivery, 2014 The conventional formulation of prednisolone is considered to be low in efficacy, primarily on account of their failure in providing and maintaining effective therapeutic drug levels. This study aims to focus on development of a mucoadhesive buccal delivery system with a twofold objective of offering a rapid as well as a prolonged delivery of ...
Rachna, Kumria +3 more
openaire +2 more sources
Pharmaceutics, 2023 The therapeutic effectiveness of paliperidone in the treatment of schizophrenia has been limited by its poor oral bioavailability; hence, an alternative route could be appropriate.
Fahad Mohammed AlMulhim +7 more
doaj +1 more source
Formulation and Evaluation of Biopolymer Based Buccal Film of Diclofenac Sodium
Journal of Basic and Applied Research in Biomedicine, 2022 Buccal drug delivery gives easier and safe method of drug administration because in case of toxicity it can be terminated by simply removing the dosage form from buccal cavity.
Pooja Kashid +2 more
doaj +2 more sources
Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388. [PDF]
, 2020 COR388, a small-molecule lysine-gingipain inhibitor, is currently being investigated in a Phase 2/3 clinical trial for Alzheimer's disease (AD) with exploratory endpoints in periodontal disease.
Arastu-Kapur, Shirin +10 more
core +1 more source
Pharmaceutics, 2023 The mucosal membrane of the oral cavity, due to its unique structure and availability, constitutes an appropriate site for the delivery of drugs, both with local and systemic effects.
Marta Szekalska +6 more
doaj +1 more source