Results 41 to 50 of about 2,290,590 (298)

Novel development of Poly(2-ethyl-2-oxazoline)-based mucoadhesive buccal film for poorly water-soluble drug delivery via hot-melt extrusion.

European journal of pharmaceutics and biopharmaceutics
Ziru Zhang, Sheng Feng, Rasha El-Kanayati, Indrajeet Karnik, S. Vemula, Michael A. Repka   +5 more
semanticscholar   +2 more sources

Buccal Thin Films as Potent Permeation Enhancers for Cytisine Transbuccal Delivery

Membranes, 2022
Cytisine (CYT) is a powerful anti-smoking compound which could greatly benefit from transbuccal delivery because of both its unfavorable pharmacokinetics after oral administration and its intrinsic ability to permeate the buccal mucosa. This work aims to
Viviana De Caro, Giuseppe Angellotti, Fabio D’Agostino, Giulia Di Prima   +3 more
doaj   +1 more source

Single-Dose Pharmacokinetics of Fentanyl Buccal Soluble Film [PDF]

Pain Medicine, 2010
The objectives of the study were to determine the absolute bioavailability of fentanyl from fentanyl buccal soluble film, estimate the percentage of a fentanyl dose absorbed through the buccal mucosa, and compare the bioavailability of equivalent doses administered either as single or multiple dose units.Open-label, randomized, four-period, Latin ...
Vasisht, Niraj, Gever, Larry N, Tagarro, Ignacio, Finn, Andrew L   +3 more
openaire   +2 more sources

Immunopathogenesis of canine chronic ulcerative stomatitis. [PDF]

, 2020
Canine Chronic Ulcerative Stomatitis is a spontaneously occurring inflammatory disease of the oral mucosa. An immune-mediated pathogenesis is suspected though not yet proven.
Anderson, JG, Bizikova, P, Ford, K, Jimenez, RJ, Kol, A, Murphy, BG, Stapelton, BP, Vasilatis, D, Villarreal, A   +8 more
core   +1 more source

Formulation and evaluation of buccal film of an antihypertensive drug

Journal of Innovations in Applied Pharmaceutical Science (JIAPS), 2023
The aim of the study was to formulate and evaluate Losartan potassium buccal films, an angiotensin receptor blocker and is used to treat hypertension. Losartan potassium is having less bioavailability (33%), so the buccal films are expected to increase ...
Ashinaa Benedict, Irin rose Paul, M. M. Mathews, B. R   +3 more
semanticscholar   +1 more source

Formulation and Characterization of Nicotine Microemulsion-Loaded Fast-Dissolving Films for Smoking Cessation

Molecules, 2022
The present study aimed to develop a nicotine microemulsion (NCT-ME) and incorporate it into a fast-dissolving film. The NCT-ME was prepared by mixing the specified proportions of nicotine (NCT), surfactant, co-solvent, and water. The NCT-ME was measured
Kantaporn Kheawfu, Pattaraporn Panraksa, Pensak Jantrawut   +2 more
doaj   +1 more source

Polysaccharide food matrices for controlling the release, retention and perception of flavours [PDF]

, 2018
Polysaccharides have many roles across both the food and pharmaceutics industries. They are commonly used to enhance viscosity, stabilise emulsions and to add bulk to food products.
Cook, Sarah L., Khutoryanskiy, Vitaliy V., Methven, Lisa, Parker, Jane K.   +3 more
core   +1 more source

Solid and Semisolid Innovative Formulations Containing Miconazole-Loaded Solid Lipid Microparticles to Promote Drug Entrapment into the Buccal Mucosa

Pharmaceutics, 2021
The currently available antifungal therapy for oral candidiasis (OC) has various limitations restricting its clinical use, such as short retention time, suboptimal drug concentration and low patients compliance. These issues could be overcome using micro
Viviana De Caro, Libero Italo Giannola, Giulia Di Prima   +2 more
doaj   +1 more source

Silodosin oral films: Development, physico-mechanical properties and in vitro dissolution studies in simulated saliva [PDF]

, 2019
Sublingual film dosage forms for drugs used for fast symptomatic treatment have promise because they allow a rapid onset of action. The aim of this study was to prepare films of silodosin intended for sublingual administration for the symptomatic ...
Adair, Alhayali, Allam, Alonzo, Boateng, Brady, Brouwers, Campisi, Chapple, Curatolo, De Caro, El-Setouhy, ElMeshad, Gao, Garsuch, Gittings, Guo, Hanif, Hobbs, Huang, Humphrey, Jug, Kalia, Kapoor, Kim, Koland, Korhonen, Li, Liew, Madhav, Mashru, Matsubara, Miller-Chou, Montorsi, Nagy, Patel, Prabhu, Prasad, Preis, Preis, Preis, Radebaugh, Repka, Rossi, Runja, Sharma, Singh, Singh, Singh, Singh, Slavkova, Tanno, Vila, Visser, Vuddanda, Vuddanda, Yang, Zhang   +57 more
core   +2 more sources

Formulation and evaluation of nitrendipine buccal films

Indian Journal of Pharmaceutical Sciences, 2008
A mucoadhesive drug delivery system for systemic delivery of nitrendipine, a calcium channel blocker through buccal route was formulated. Mucoadhesive polymers like hydroxypropylmethylcellulose K-100, hydroxypropylcellulose, sodium carboxymethylcellulose, sodium alginate, polyvinyl alcohol, polyvinyl pyrrolidone K-30 and carbopol-934P were used for ...
Nappinnai, M., Chandanbala, R., Balaijirajan, R.   +2 more
openaire   +3 more sources