Results 41 to 50 of about 407,065 (213)

The Governance Gap: Democratizing Drug Development Through Decision Architecture

Clinical Pharmacology &Therapeutics, EarlyView.
Drug development is most exposed to governance failure where it can least afford it, in global health. The field has more predictive power than at any point in its history and roughly the same failure rate it had a decade ago. We argue that this paradox persists because the field has invested heavily in prediction science while neglecting decision ...
Craig R. Rayner, Nancy E. Martin, Danielle Smith, Eliza Kruger, Carl M.J. Kirkpatrick, Goonaseelan (Colin) Pillai, Katy Moore, Darrell Nix, Cristina Donini, Jakob P. Cramer, Edmundo Muniz, Natalia Muniz, Ernst Bos, Douglas McNair, Shyam Bhaskaran, Mark Sullivan, Dan Hartman   +16 more
wiley   +1 more source

Two‐Stage Power Management for Triboelectric Nanogenerators: Toward Reliable and Efficient Self‐Powered Systems

Safety Science and Technology, EarlyView.
This review systematically outlines two‐stage power management circuits for TENGs, integrating AC–DC and DC–DC conversion to overcome high impedance and unstable output. It highlights strategies for efficient energy extraction and stable power delivery, enabling the development of reliable self‐powered systems for safety monitoring and applications in ...
Jiaxin Hu, Zhiyong Zhang, Haiyang Shao, Tianyu Shi, Baoling Yuan, Ming‐Lai Fu   +5 more
wiley   +1 more source

Recent Advances in Oriented Hydrogels: From Fundamental Mechanisms to Future Challenges

SusMat, EarlyView.
Traditional hydrogels suffer from weak mechanical properties and limited functionality due to their random polymer networks. This review comprehensively summarizes the reinforcement mechanisms of oriented structure for hydrogels, the design/fabrication strategies, and the latest application progress of high‐strength oriented hydrogels.
Chang Xu, Xijing Zhuang
wiley   +1 more source

NanoSentry: An Edge‐Deployable Unified Neural Architecture for Multi‐Domain Industrial Prognostics and Health Management

Artificial Intelligence for Engineering, EarlyView.
NanoSentry, a sub‐50 KiB unified architecture for multi‐domain prognostics, matches or outperforms models 4.5× $4.5\times $ larger across turbofan, battery, and bearing benchmarks while reducing end‐of‐life prediction error up to 5.8× $5.8\times $. Physical STM32H7 deployment confirms sub‐3 ms inference and up to 26 KiB peak SRAM without quantisation ...
Naem Azam Chowdhury, Abu Nasek, Khan Prottoy, Md Hamid Borkot Tulla, Jafor Sadik Chowdhury   +4 more
wiley   +1 more source

Efficient integration of buck converter into an active rectifier for DC-fault current limitation in DC networks

e-Prime: Advances in Electrical Engineering, Electronics and Energy
Voltage Source Converters (VSCs) operating as active rectifiers inherently lack current-limiting capabilities for faults occurring on the DC side due to the presence of freewheeling diodes in IGBT or MOSFET structures.
Evangelos E. Pompodakis, Georgios I. Orfanoudakis   +1 more
doaj   +1 more source

Exchange‐Rate Responses to Structural Oil‐Market Shocks: Revisiting Krugman's Real–Financial Adjustment Framework

Australian Economic Papers, EarlyView.
ABSTRACT This study examines how structural oil‐market shocks affect exchange rates through the real and financial adjustment mechanisms proposed by Krugman (1983). Using a two‐stage SVAR–ARDL/NARDL framework, we identify oil supply, aggregate demand, and oil‐specific demand shocks and estimate their symmetric and asymmetric effects for oil‐importing ...
Jungho Baek, Min‐Joon Kim
wiley   +1 more source

Letter to Alfred H. Buck and his wife from ''Brother''Charles Buck, 1870 May 16 [PDF]

, 1870
A handwritten letter to Alfred H. Buck and his wife from ''Brother'' Charles Buck dated May 6, 1870. It regards three drafts enclosed for $500.00 each and one draft for $192.91 from their father's estate settlement.Archival master image scanned in ...
Buck, Charles
core   +1 more source

A New Single-Stage Four-Switch Common-Ground-Type Buck–Boost Inverter

Energies
The output voltages of photovoltaic panels typically fluctuate due to variations in environmental conditions, and therefore the use of a buck–boost inverter is essential. This article presents a novel buck–boost voltage-source inverter topology.
Abd Ullah, Yong-Ho Park, Youn-Ok Choi
doaj   +1 more source

THE TRANSCALAR POLITICS AND SPATIAL IMPLICATIONS OF INVESTMENTS IN SHOPPING MALLS IN AFRICAN CITIES: A Study of Accra's West Hills Mall, Ghana

International Journal of Urban and Regional Research, EarlyView.
Abstract A surge in the number of shopping malls across many African cities reflects capital's responses to the continent's growing middle class and deepening neoliberal globalization. This article develops an analysis of the transcalar nature of these urban investments using the case of the West Hills Mall (WHM) in the Greater Accra Metropolitan Area (
Rosina Sheburah Essien, George Owusu, Kofi Kekeli Amedzro, Musah Aziba Issah, Jennifer Robinson, John Spyropoulos   +5 more
wiley   +1 more source

Two-Domains Control of a Buck Converter

E3S Web of Conferences, 2017
In the design of a power converter, the maximum output voltage transient under load change is one of the main drivers. The ECSS-E-ST-20C imposes specific requirements on the power quality of a regulated bus, which result most of the time in the use of a ...
Triggianese Mariel, Carbonnier Hadrien, Tonicello Ferdinando, Rogina Maria Rodriguez   +3 more
doaj   +1 more source