Results 31 to 40 of about 893 (260)

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Adaptive Collision Sensitivity for Efficient and Safe Human–Robot Collaboration

Advanced Intelligent Systems, EarlyView.
An adaptive collision‐sensitivity framework uses each robot link's effective mass to estimate contact forces online and decide when collaborative robots should stop or continue. Tested on simulated and real UR10e and simulated KUKA arms, it maintains conservative force estimates while reducing unnecessary stops and increasing task productivity. What is
Lukas Rustler, Matej Misar, Matej Hoffmann   +2 more
wiley   +1 more source

Numerical Simulation of Vertical Cyclic Responses of a Bucket in Over-Consolidated Clay

Journal of Marine Science and Engineering
Multi-bucket foundations have become an alternative for large offshore wind turbines, with the expansion of offshore wind energy into deeper waters. The vertical cyclic loading–displacement responses of the individual bucket of the tripod foundation are ...
Jun Jiang, Chengxi Luo, Dong Wang
doaj   +1 more source

Influencing Factors of Motion Responses for Large-Diameter Tripod Bucket Foundation

Applied Sciences, 2019
Large-diameter multi-bucket foundation is well suited for offshore wind turbines at deeper water than 20 m. Air floating transportation is one of the key technologies for the cost-effective development of bucket foundation.
Xianqing Liu, Puyang Zhang, Mingjie Zhao, Hongyan Ding, Conghuan Le   +4 more
doaj   +1 more source

Expectations and Reality: The Lived Experiences of Australians With Psychosocial Disability Within the NDIS

Australian Journal of Social Issues, EarlyView.
ABSTRACT While Australia's National Disability Insurance Scheme (NDIS) was founded on principles of choice and control, for people with significant mental health challenges (what the NDIS calls ‘psychosocial disability’) these ideals often remain elusive. Support systems continue to be fractured and in the context of ongoing policy reforms, it is vital
Joel Hollier, Jennifer Smith‐Merry
wiley   +1 more source

Bearing Capacity of Offshore Wind Power Suction Bucket with Supports Under Extreme Wind and Waves

Energies
In this study, we analyzed an offshore wind turbine suction bucket foundation with supports, referred to as the supported suction bucket foundation.
Changfeng Yuan, Qiming Zhang, Husheng Luo, Kaiwen Zhang   +3 more
doaj   +1 more source

A Numerical Analysis on Lateral Resistance of Pile–Bucket Foundation for Offshore Wind Turbines

Applied Sciences, 2022
The large-diameter single pile has been widely used in marine wind turbine foundations. In order to improve its lateral bearing capacity, the suction bucket foundation (BF) can be used as a reinforcement method, which surrounds the periphery of the ...
Zonghao Yuan, Ke Zhong, Xiaoqiang Wang, Xiaodong Pan, Ben He, Jing Wu, Jiankun Zhang, Shiwu Xu   +7 more
doaj   +1 more source

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu, Weifeng Guo, Jianxiang Li, Tiange Zhang, Dan Xu   +4 more
wiley   +1 more source

Experiment and analysis on penetration of suction bucket foundation

Shuili Shuiyun Gongcheng Xuebao, 2021
As a new type of foundation, the suction bucket foundation has good technical and economic performances compared with traditional foundations. The key construction parameter, soil plug, and construction efficiency are analyzed through model tests of a ...
FU Kun, LIU Zhanguo, YIN Liaoyuan, LI Sen   +3 more
doaj   +1 more source