Results 191 to 200 of about 552,293 (286)

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Economic evaluation of single-inhaler triple therapy for chronic obstructive pulmonary disease in Thailand. [PDF]

BMJ Open Respir Res
Dilokthornsakul P, Dilokthornsakul P, Chongmelaxme B, Niyompattama A.   +3 more
europepmc   +1 more source

The Metabolic Role of Mitochondria in the Perinatal Cardiac Development and Cardiovascular Diseases

Exploration, EarlyView.
This review explores the critical role of mitochondria in heart development and cardiovascular disease. It highlights how mitochondrial maturation during embryonic‐to‐postnatal transition, regulated by oxygen and metabolic changes, shapes cardiac structure and function.
Minghao Li, Ruiyi Zhang, Xinyuan Li, Hefeng Huang   +3 more
wiley   +1 more source

An Efficient Micropropagation Protocol for <i>Camellia chekiangoleosa</i> 'Ganhongyou 1' via Stem Segment Culture. [PDF]

Plants (Basel)
Liu A, Peng Y, Chen X, Cheng Q, Zha K, Wen Q.   +5 more
europepmc   +1 more source

A Finger Bud [PDF]

BMJ, 1953
openaire   +2 more sources

Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices

Exploration, EarlyView.
This review summarizes recent advances in liver‐on‐a‐chip (LOC) technologies, including fabrication strategies and functional integration approaches, and discusses their promising applications in drug screening and related biomedical fields. ABSTRACT Reliable in vitro liver models are indispensable for researching liver diseases and developing ...
Jie Wang, Ziwei Liang, Jiapu Wang, Zongyi Li, Shaojie Wang, Yan Wei, Xin Xie, Di Huang   +7 more
wiley   +1 more source

Fine-Grained Detection and Sorting of Fresh Tea Leaves Using an Enhanced YOLOv12 Framework. [PDF]

Foods
Zhao S, Ye C, Lian C, Mei L, Wu L, Chen J.   +5 more
europepmc   +1 more source

RBFOX1 Dysfunction Unlocks APOE4‐Associated Microglial Genesis and Exacerbates Alzheimer's Pathology in Human Cerebral Organoids

Exploration, EarlyView.
Genomic studies implicate RBFOX1 in Alzheimer's disease (AD) risk, highlighting the need to define its role and interactions with other risk factors. Here, CRISPR/Cas9‐mediated RBFOX1 loss in APOE4 human cerebral organoids induces autonomous microglial genesis and accelerates AD pathology, revealing a protective role of RBFOX1 and establishing a model ...
Bowen Zhang, Changjie Shi, Jiayi Zhao, Qiuhong Hua, Houchun Zhang, Hailin Gao, Yuanyuan Qian, Jiaxue Cha, Jing Li, Jiayao Chen, Tae‐Hyung Kim, Jianhuang Xue, Yujun Hou, Ru Zhang   +13 more
wiley   +1 more source

Single-cell transcriptional profiling revealed the protective effects of Buddleoside in sepsis-associated acute liver injury. [PDF]

Front Immunol
Shi Q, Lou N, Fu L, Wang Y, Xue C, Shen S, Li L.   +6 more
europepmc   +1 more source

GC × GC‐TOF MS and Sensory Profiling of Aroma Compounds in Magnolia Species: Effects of Processing Methods on Volatile Retention in M. wufengensis

Flavour and Fragrance Journal, EarlyView.
The first comparative analysis of Magnolia scents reveals that M. wufengensis is characterised by a high aldehyde content, exhibiting a fresh, sweet, and fruity fragrance profile. Furthermore, freeze‐drying preserves 6.7 times more 2‐nonenal compared to shade‐drying, highlighting its superior efficacy in retaining key volatile compounds.
Xiaole Wang, Zhonghua Du, Lei Xu, Junjie Hu, Tao Xiong, Chiqing Chen, Lichun Ye, Zhaohua Shi   +7 more
wiley   +1 more source