Results 131 to 140 of about 58,384 (313)
Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling. [PDF]
, 2013 Smoothened (Smo) is a member of the Frizzled (FzD) class of G-protein-coupled receptors (GPCRs), and functions as the key transducer in the Hedgehog (Hh) signalling pathway.
Bao, Ju +8 more
core +1 more source
Gastroenterology, 2018 BACKGROUND & AIMS Lymphocytic colitis is a common cause of chronic, nonbloody diarrhea. However, the effects of treatment are unclear and randomized placebo-controlled trials were requested in a Cochrane review.
Stephan Miehlke +39 more
semanticscholar +1 more source
Clinical and Translational Allergy, Volume 16, Issue 2, February 2026.ABSTRACT Primary diffuse type 2‐dominant chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory disease of the nasal cavity and paranasal sinuses associated with significant morbidity. Impaired sense of smell is a cardinal symptom of CRSwNP and one of the most burdensome for patients, impacting quality of life, mental health, and even ...
Thomas S. Higgins +9 more
wiley +1 more source
Journal of Crohn's & Colitis, 2017 Background and Aims: Safety and efficacy of budesonide multimatrix, an oral extended-release second-generation corticosteroid designed for targeted delivery throughout the colon, were examined for induction of remission in patients with mild to moderate ...
D. Rubin +9 more
semanticscholar +1 more source
Suppressive CD8+ T‐Cells Are Key Cellular Mediators of Extracorporeal Photopheresis
Journal of Clinical Apheresis, Volume 41, Issue 1, February 2026.ABSTRACT Extracorporeal photopheresis (ECP) is a widely utilized immunomodulatory procedure with an incompletely defined mechanism. In graft‐versus‐host disease (GvHD) and transplant rejection, ECP is thought to induce immune tolerance by increasing regulatory CD4+ T‐cells, whereas in cutaneous T cell lymphoa it may enhance dendritic cell–mediated ...
Kai J. Rogers +7 more
wiley +1 more source
Budesonide for the Treatment of Inflammatory Bowel Disease
Canadian Journal of Gastroenterology, 1994 While corticosteroids are the most effective treatment for the symptomatic management of patients with inflammatory bowel disease (IBD), they cause serious side effects.
Gordon R Greenberg
doaj +1 more source
Review 2: "Inhaled budesonide in the treatment of early COVID-19 illness: a randomised controlled trial" [PDF]
, 2021 Ariel Berlinski
openalex +1 more source
JGH Open, Volume 10, Issue 2, February 2026.ABSTRACT Aims Proton pump inhibitors (PPIs) and potassium‐competitive acid blockers (PCABs) are widely used for acid‐related disorders. Recent studies have raised concerns that acid suppression may alter gut microbiota and drug pharmacokinetics, potentially influencing therapeutic outcomes in patients with inflammatory bowel disease.
Shinsuke Otagiri +4 more
wiley +1 more source
Drug points: Anaphylactic-like reaction associated with oral budesonide [PDF]
, 2000 Marten Heeringa
openalex +1 more source
Journal of the Canadian Association of Gastroenterology, 2018 Background Budesonide is an oral glucocorticoid designed for the treatment of inflammatory bowel disease (IBD) that may reduce systemic adverse events (AEs).
M. Kuenzig +7 more
semanticscholar +1 more source