Results 111 to 120 of about 26,503 (228)

Differential anti-inflammatory effects of budesonide and a p38 MAPK inhibitor AZD7624 on COPD pulmonary cells

open access: yes, 2018
Andrew Higham,1,2 Pradeep Karur,1,2 Natalie Jackson,2 Danen M Cunoosamy,3 Paul Jansson,3 Dave Singh1,2 1Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic
Higham A   +5 more
core  

Chronic Rhinosinusitis and Nasal Polyps in Eosinophilic Granulomatosis With Polyangiitis: A Scoping Review

open access: yesInternational Forum of Allergy &Rhinology, Volume 16, Issue 9, Page 996-1011, September 2026.
ABSTRACT Background Chronic rhinosinusitis (CRS) is one of the most common manifestations of eosinophilic granulomatosis with polyangiitis (EGPA), often preceding the diagnosis of systemic vasculitis by several years. The sinonasal presentation of EGPA typically resembles CRS with nasal polyps (CRSwNP), making it clinically indistinguishable from those
Alisha Sharma   +12 more
wiley   +1 more source

Risk of venous thromboembolism after SARS‐CoV‐2 vaccination—Evidence from genome‐wide association study and population‐based observational study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3246-3256, September 2026.
Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind   +7 more
wiley   +1 more source

Comparison of the Consequences of Intratracheal Administration of Surfactant Plus Budesonide with Surfactant alone in Preterm Infants with Respiratory Distress Syndrome [PDF]

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان
Background and Aim: To control complications in infants with respiratory distress syndrome, surfactants and auxiliary drugs such as budesonide are used to reduce the inflammatory reactions of the airways. The aim of this study is to compare the effect of
Morteza Habibi, Fatemeh Toohidinia
doaj  

Population Pharmacokinetics and Dose De‐Escalation Regimens of Subcutaneous Vedolizumab in Inflammatory Bowel Disease

open access: yesJCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Background Vedolizumab is a therapeutic antibody approved for the treatment of Crohn's disease and ulcerative colitis. The population pharmacokinetics (popPK) of intravenous (IV) administered vedolizumab have been described, but remain to be defined for subcutaneous (SC) administration.
S. I. Anjie   +5 more
wiley   +1 more source

Change in (A) total asthma symptoms and (B) reliever medication-free days following treatment with budesonide pMDI, budesonide/formoterol DPI or budesonide/formoterol pMDI

open access: yes, 2011
Copyright information:Taken from "Therapeutic comparison of a new budesonide/formoterol pMDI with budesonide pMDI and budesonide/formoterol DPI in asthma"International Journal of Clinical Practice 2007;61(11):1874-1883.Published online Jan 2007PMCID ...
S Peterson (96080)   +3 more
core   +1 more source

Bronchiectasis as an Underrecognized Extraintestinal Manifestation of Inflammatory Bowel Disease

open access: yesJCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Introduction Inflammatory bowel diseases (IBD) are chronic inflammatory diseases of the gastrointestinal tract, often presenting with extraintestinal manifestations (EIMs). The most prevalent pulmonary EIM is IBD‐associated bronchiectasis (IBD‐BE), which is often overlooked.
Lynn te Slaa   +2 more
wiley   +1 more source

Isolated Mild Hyperemia Identified by Intestinal Ultrasound Is Associated With Adverse Outcomes in Inflammatory Bowel Disease

open access: yesJCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Background Increased bowel wall thickness (BWT) measured by intestinal ultrasound (IUS) is the most predictive sonographic parameter of endoscopic disease activity in Crohn's disease (CD) and ulcerative colitis (UC). The clinical significance of hyperemia in the absence of increased BWT has yet to be delineated.
Noa Krugliak Cleveland   +8 more
wiley   +1 more source

Next‐Generation Pluronic Micelles for Advanced Drug Delivery Application

open access: yesMacromolecular Materials and Engineering, Volume 311, Issue 9, September 2026.
The present review provides a comprehensive overview of Pluronic‐based micelles for advanced drug and gene delivery. It highlights their structure, classification, synthesis, self‐assembly, and functionalization, as well as their biocompatibility and stimuli‐responsive properties.
Manoj Gundeti   +6 more
wiley   +1 more source

Net Renal Drug Secretion Critically Requires Significant Contribution of Basal Uptake Transporters: Perspective From Mechanistic Kidney Model Simulation and Integration of Clinical and In Vitro Data

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACT Renal clearance (CLr) is the net outcome of glomerular filtration, secretion, and reabsorption, which makes the quantitative requirements for net renal secretion difficult to infer from simple clearance models. Using a mechanistic kidney model (MechKiM), we simulated blood‐referenced CLr (CLr,b) for 30,000 virtual drugs (neutral, monoanionic ...
Toshiaki Tsuchitani   +2 more
wiley   +1 more source

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