Results 131 to 140 of about 38,435 (236)

Rosa roxburghii‐Derived Exosome‐Like Nanovesicles Alleviate Ulcerative Colitis Based on Th17/Treg Immune Balance and Gut Microbiota Modulation

Food Frontiers, Volume 7, Issue 3, May 2026.
Rosa roxburghii‐derived exosome‐like nanovesicles target the intestine, repairing barriers, regulating gut microbiota, balancing Th17/Treg, and combating oxidative stress/inflammation to alleviate colitis, a promising UC therapy. ABSTRACT Plant‐derived nanovesicles (PDVs), an innovative and bioactive form of natural products, are key mediators of ...
Yuanyuan Wang, Yan Zeng, Guoying Liu, Hai Zou, Jie Wang, Jun Zhang, Ketao Jin, Zhangfeng Zhong, Xiaozhou Mou   +8 more
wiley   +1 more source

Corticosteroid Administration to Prevent Complications of Anterior Cervical Spine Fusion: A Systematic Review. [PDF]

, 2018
Study Design: Systematic review. Objectives: Anterior cervical approach is associated with complications such as dysphagia and airway compromise. In this study, we aimed to systematically review the literature on the efficacy and safety of corticosteroid
Abedi, Aidin, Bonaki, Hirbod Nasiri, Jazayeri, Seyed Behnam, Rahimi-Movaghar, Vafa, Vaccaro, Alexander R., Zadegan, Shayan Abdollah   +5 more
core   +1 more source

Multicenter experience using tofacitinib for treatment of refractory pediatric inflammatory bowel diseases in the United States

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 5, Page 1218-1225, May 2026.
Abstract Objectives Tofacitinib is a selective Janus kinase (JAK‐1) inhibitor approved for the treatment of ulcerative colitis (UC) in adults. Data is limited in the pediatric population. The aim of this study was to evaluate the efficacy of tofacitinib in pediatric inflammatory bowel disease (IBD).
Denise D. Young, Jennifer E. Murphy, Mallory Chavannes, Jennifer L. Dotson, Jeanne Tung, Erica Chang, Brad Pasternak, Erin Crawford, Nancy McGreal, Jonathan Moses, Sandra C. Kim   +10 more
wiley   +1 more source

Dupilumab as an effective therapy for eosinophilic esophagitis in pediatric patients weighing less than 15 kilograms

JPGN Reports, Volume 7, Issue 2, Page 185-191, May 2026.
Abstract Objectives Eosinophilic esophagitis (EoE) is a type 2 cytokine‐mediated chronic inflammatory condition leading to esophageal dysfunction. Dupilumab blocks IL‐4 and IL‐13 signaling, which are key inflammatory mediators in EoE and other allergic disorders.
Sindhura Kasturi, Tanaz Danialifar, Thirumazhisai Gunasekaran, Nick Shillingford, Paul Zamiara, Vrinda Bhardwaj, Melinda Braskett   +6 more
wiley   +1 more source

Case series: Joubert syndrome and eosinophilic esophagitis

JPGN Reports, Volume 7, Issue 2, Page 329-331, May 2026.
Abstract Joubert syndrome (JS) is a rare genetic disorder characterized by developmental abnormalities, particularly in the brainstem and cerebellar vermis, alongside multisystem manifestations such as kidney and liver anomalies, polydactyly, cleft lip or palate, and tongue defects.
Jonathon Schening, Stephanie Leon‐Paredes, Eric Chiou, Vibha Szafron, Anthony Olive, Sara Anvari   +5 more
wiley   +1 more source

Therapeutic drug monitoring of corticosteroids/β2-agonists in the hair of patients with asthma: an open-label feasibility study

Frontiers in Pharmacology
Background: Although adherence to inhaled medication is critically important for treatment efficiency, around half of patients taking these drugs are non-adherent or make critical errors when using their delivery device.
Hélène Salvator, Hélène Salvator, Hélène Salvator, Elodie Lamy, Camille Roquencourt, Emmanuelle Bardin, Emmanuelle Bardin, Emmanuelle Bardin, Philippe Devillier, Philippe Devillier, Stanislas Grassin-Delyle, Stanislas Grassin-Delyle   +11 more
doaj   +1 more source

Prevalence of Contact Sensitisation Among Patients With Atopic Dermatitis in Thailand: A 20‐Year Retrospective Study

Contact Dermatitis, Volume 94, Issue 6, Page 689-693, June 2026.
Silada Kanokrungsee, Rungsima Kiratiwongwan, Nicha Wareesawetsuwan, Sasitorn Yenyuwadee, Pichanee Chaweekulrat, Titinun Kumpangsin, Waranya Boonchai   +6 more
wiley   +1 more source

Collagenous gastritis: A cause of anemia and gastric nodularity in the pediatric population

JPGN Reports, Volume 7, Issue 2, Page 231-235, May 2026.
Abstract We present a case series of seven pediatric patients with collagenous gastritis (CG) with the aim of contributing data to existing literature about this rare disease to assist in the understanding and management of these patients. Gross nodularity seen on esophagogastroduodenoscopy and increased subepithelial collagen on biopsy were noted in ...
Megan Emiliani, Dyer Heintz, Marisa Izaguirre   +2 more
wiley   +1 more source

Occupational Asthma and Contact Urticaria in a Wildlife Worker With Type I Hypersensitivity to Deer Dander

Contact Dermatitis, Volume 94, Issue 6, Page 717-719, June 2026.
Eglė Janušonytė, Thomas Harr, Peter Jandus, Haïg Nigolian   +3 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source