Results 131 to 140 of about 24,788 (241)

Effects of budesonide and surfactant in preterm fetal sheep

, 2018
Mechanical ventilation causes lung injury and systemic inflammatory responses in preterm sheep and is associated with bronchopulmonary dysplasia (BPD) in preterm infants. Budesonide added to surfactant decreased BPD by 20% in infants.
Masatoshi Saito, Noah H. Hillman, Kothe, T Brett, Emily Royse, Augusto Schmidt, Hillman, Noah H, Fabrizio Salomone, T. Brett Kothe, Alan H. Jobe, Gabrielle C. Musk, Salomone, Fabrizio, Matthew W. Kemp, Schmidt, Augusto, Watanabe, Shimpei, Musk, Gabrielle C, Royse, Emily, Kemp, Matthew W, Haruo Usuda, Shimpei Watanabe, Saito, Masatoshi, Usuda, Haruo, Jobe, Alan H   +21 more
core   +1 more source

A Rare Clinical Presentation of Variegate Porphyria

Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.
WGS redirected the diagnostic focus, underscoring the complex interplay between porphyria and a potential MYMK‐related neuromuscular phenotype. ABSTRACT Background Variegate porphyria is a rare heme biosynthesis disorder caused by pathogenic variants in the PPOX gene.
I. Viakhireva, A. Murtazina, A. Orlova, N. Makretskaya, S. Nikitin, M. Skoblov   +5 more
wiley   +1 more source

Clozapine‐induced diarrhea: A case report and mechanistic overview

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Abstract Background Clozapine is an atypical antipsychotic that is highly effective in managing treatment‐resistant schizophrenia. However, its use is associated with a wide range of adverse effects, including agranulocytosis, seizures, sedation, and gastrointestinal issues such as constipation, and less commonly, diarrhea. While constipation is a well‐
Shahab Dastmardi, Soha Namazi
wiley   +1 more source

Use of Home Spirometry for Steroid Tapering

Respirology Case Reports, Volume 14, Issue 6, June 2026.
Organizing pneumonia (OP) is a late, non‐infectious pulmonary complication that occurs following hematopoietic cell transplant (HCT) and treatment typically involves protracted courses of corticosteroids that are associated with dose‐limiting adverse effects and pulmonary exacerbations upon corticosteroid tapering.
Zayan Musa, Carson Tyler Moss, Carlos Daniel Hernandez Borges, Husham Sharifi, Joe Hsu   +4 more
wiley   +1 more source

Removal of a Fishhook‐Shaped Foreign Body in the Bronchus and Literature Review

Respirology Case Reports, Volume 14, Issue 6, June 2026.
Fishhook‐shaped bronchial foreign bodies are rare and difficult to remove. We report a case of a fishhook‐shaped foreign body in the basal segment of the right lower lobe removed via rigid bronchoscopy combined with flexible bronchoscopy. The value of the combined use of rigid and flexible bronchoscopy for foreign body removal is emphasised.
Wan Hu, Fanrui Zeng
wiley   +1 more source

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

Respirology, Volume 31, Issue 6, Page 561-577, June 2026.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

Rectal budesonide and mesalamine formulations in active ulcerative proctosigmoiditis: efficacy, tolerance, and treatment approach

, 2016
George P Christophi, Arvind Rengarajan, Matthew A Ciorba Division of Gastroenterology, Washington University School of Medicine, St.
Christophi GP, Rengarajan A, Ciorba MA
core  

Understanding Patient and Gastroenterologist Preferences at the Time of Treatment Escalation to First‐Line Advanced Therapy in Ulcerative Colitis: A Discrete Choice Experiment in Five European Countries

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Background With guidelines recommending earlier advanced therapy (AT) use after 5‐ASA failure for patients with moderately‐to‐severely active ulcerative colitis (UC), it is important to explore treatment preferences at the point of escalation to first‐line AT.
Stefan Schreiber, Alissa Walsh, Peter Hur, Laura Panattoni, Brett Hauber, Natalie Land, Josh Coulter, Grace Gahlon, Karolina Wosik, Joseph C. Cappelleri, Melissa Culhane Maravic, Xiang Guo, Anthony Buisson   +12 more
wiley   +1 more source

Artificial Intelligence Versus Conventional Scoring for Assessing Small Bowel Capsule Endoscopy Cleanliness in Crohn's Disease

United European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Background and Aims Evaluation of cleanliness in capsule endoscopy is essential to validate the exam. However, reliable evaluation of bowel cleanliness remains challenging. The validated KODA score provides robust assessment but is time‐consuming and impractical in routine practice.
Raphaëlle Rouveyre, Catherine Le Berre, Romain Leenhardt, Michael Collins, Astrid De Massin, Mathurin Flamant, Caroline Trang‐Poisson, Guillaume Bouguen, Nina Dib, Aymeric Histace, Theo Soude, Xavier Dray, Arnaud Bourreille   +12 more
wiley   +1 more source

Transcriptional Modulation of the Nrf2 Antioxidant Pathway and Tight Junctions by a Plant Sterol Food Supplement in an Intestinal Inflammation Coculture Model

Journal of Food Science, Volume 91, Issue 6, June 2026.
ABSTRACT There is growing evidence supporting the anti‐inflammatory activity of plant sterols (PS) in preclinical models of intestinal inflammation. However, the underlying mechanisms driving these beneficial effects remain incompletely understood. This study investigates the transcriptional modulatory activity of a PS food supplement (PS‐FS) on genes ...
Mussa Makran, Ilenia Concetta Giardina, Guadalupe Garcia‐Llatas, Alessandro Attanzio, Antonio Cilla   +4 more
wiley   +1 more source