Results 131 to 140 of about 4,351,429 (251)

INDEX ACCESS WITH A FINITE BUFFER ABSTRACT:

open access: yes, 2008
A buffer is a main-memory area used to reduce access to disks. The buffer holds pages from secondary storage files. A process request-ing a page causes a fault if the page is not in the buffer: the requested page is read into the buffer.
Giovanni Maria Sacco
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Development of a network buffer for a Quantum Random Number Generator

open access: yes
openQuesta tesi presenta lo sviluppo di un buffer di rete generalizzato per la distribuzione in tempo reale degli eventi generati da un QRNG (Quantum Random Number Generator) e acquisiti tramite tre timetagger diversi (fake, quTAG, Swabian). Inizialmente
GOBBO, LORENZO KAROL
core  

A CNN-based approach to riparian buffer strip quality monitoring in agricultural areas using satellite imagery. [PDF]

open access: yesEnviron Monit Assess
de la Sablonnière S   +4 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Evaluation of a phage-inclusive multimodal strategy for recurrent urinary tract infections. [PDF]

open access: yesBMC Microbiol
Lieberknecht-Jouy SC   +11 more
europepmc   +1 more source

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