Results 121 to 130 of about 571,212 (332)
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Elements of Theory of the Correct Operations of Logistics Transforming Networks
Foundations of Management, 2017 In this paper, transformer logistics networks are treated as flow models of discrete manufacturing systems (FMDMS). The purpose is to formalize FMDMS into logical formulas called transformer functions.
Krupa Tadeusz
doaj +1 more source
Railway scheduling reduces the expected project makespan. [PDF]
The Critical Chain Scheduling and Buffer Management (CC/BM) methodology, proposed by Goldratt (1997), introduced the concepts of feeding buffers, project buffers and resource buffers as well as the roadrunner mentality.
Demeulemeester, Erik, Tian, Wendi
core
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
THE GROWTH OF ESCHERICHIA COLI IN BUFFER SUBSTRATE AND DISTILLED WATER [PDF]
, 1955 Ellen I. Garvie
openalex +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Grassland bird nest ecology and survival in upland habitat buffers near wooded edges
Wildlife Society Bulletin, 2011 Upland habitat buffers (i.e., strips of noncrop, herbaceous vegetation) that are established adjacent to wooded fencerows offer landowners an economical option to provide wildlife benefits within intensive agricultural landscapes.
Ross R. Conover +2 more
doaj +1 more source
Glyoxalines: the determination of their pK values and the use of their salts as buffers [PDF]
, 1938 A. H. M. Kirby, A. Neuberger
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
EFFECTS OF pH AND THE COMPONENTS OF BICARBONATE AND PHOSPHATE BUFFERED SOLUTIONS ON THE METABOLISM OF POTATO DISCS AND THEIR ABILITY TO ABSORB IONS [PDF]
, 1941 F. C. Steward, Christopher Preston
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