Results 121 to 130 of about 582,767 (331)
Railway scheduling reduces the expected project makespan. [PDF]
The Critical Chain Scheduling and Buffer Management (CC/BM) methodology, proposed by Goldratt (1997), introduced the concepts of feeding buffers, project buffers and resource buffers as well as the roadrunner mentality.
Demeulemeester, Erik, Tian, Wendi
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Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Model-Based Adaptation of Software Communicating via FIFO Buffers [PDF]
, 2015 Software Adaptation is a non-intrusive solution for composing black-box components or services (peers) whose individual functionality is as required for the new system, but that present interface mismatch, which leads to deadlock or other undesirable ...
Canal-Velasco, Jose Carlos +1 more
core
GERMINATION OF CLOSTRIDIUM SPORES IN BUFFERED GLUCOSE [PDF]
, 1954 E. Staten Wynne +2 more
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Hydrogen ions, titration and the buffer index of bacteriological media [PDF]
, 1921 J. H. Brown
openalex +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Avian Conservation and EcologySustainable forestry harvest requires a balance between resource extraction and the habitat needs of wildlife. The breeding habitat of threatened birds is often delineated for protection by surveying sites for nesting pairs and applying fixed habitat ...
Alicia M Korpach +3 more
doaj +1 more source