Results 301 to 310 of about 571,212 (332)
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Changing the Buffer in Buffered Lidocaine
Journal of Infusion Nursing, 2022Hospitalized patients require venous access for procedures, treatments, or therapies. The use of lidocaine for pain relief during central vascular access device (CVAD) insertion is a standard of practice. Lidocaine buffered with sodium bicarbonate has been shown to provide significantly more pain relief in the sensation of pain upon injection ...
Ann, Plohal +4 more
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Cold Spring Harbor Protocols, 2018
Biological reactions work well only within a narrow concentration range of hydrogen ions. Paradoxically, however, many of these reactions themselves generate or consume protons. Buffers are substances that undergo reversible protonation within a particular pH range and therefore maintain the concentration of hydrogen ions within acceptable limits. This
Michael R, Green, Joseph, Sambrook
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Biological reactions work well only within a narrow concentration range of hydrogen ions. Paradoxically, however, many of these reactions themselves generate or consume protons. Buffers are substances that undergo reversible protonation within a particular pH range and therefore maintain the concentration of hydrogen ions within acceptable limits. This
Michael R, Green, Joseph, Sambrook
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Buffer capacity of biologics—from buffer salts to buffering by antibodies
Biotechnology Progress, 2013Controlling pH is essential for a variety of biopharmaceutical process steps. The chemical stability of biologics such as monoclonal antibodies is pH‐dependent and slightly acidic conditions are favorable for stability in a number of cases. Since control of pH is widely provided by added buffer salts, the current study summarizes the buffer ...
Sven Bahrenburg +2 more
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Buffer Index and Buffer Capacity for a Simple Buffer Solution
Journal of Chemical Education, 1997Many papers that present the buffering effect of the simple buffer solution consider the notion of buffer index and buffer capacity as being equivalent. Moreover, IUPAC defies them as the same thing. According to the definition of the authors who have introduced these two units, the paper shows that there is a large difference between them.
Gabriel Balea, Veronica Chiriac
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ChemPhysChem, 2014
AbstractThis paper proposes a new type of molecular device that is able to act as an inverse proton sponge to slowly decrease the pH inside a reaction vessel. This makes the automatic monitoring of the concentration of pH‐sensitive systems possible. The device is a composite formed of an alkyl chloride, which kinetically produces acidity, and a buffer ...
Alibrandi, Giuseppe +3 more
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AbstractThis paper proposes a new type of molecular device that is able to act as an inverse proton sponge to slowly decrease the pH inside a reaction vessel. This makes the automatic monitoring of the concentration of pH‐sensitive systems possible. The device is a composite formed of an alkyl chloride, which kinetically produces acidity, and a buffer ...
Alibrandi, Giuseppe +3 more
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Nature Chemistry, 2021
Bruce C. Gibb reminds us that buffers are not necessarily innocent bystanders and that they can bind to biomacromolecules too.
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Bruce C. Gibb reminds us that buffers are not necessarily innocent bystanders and that they can bind to biomacromolecules too.
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To buffer or not to buffer, that is the question
Journal of Chemical Education, 1985Question involves the preparation of a buffer solution by a chemical reaction but does not have the resultant solution act as a buffer.
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DNA and Buffers: Are There Any Noninteracting, Neutral pH Buffers?
Analytical Biochemistry, 2000The interaction of DNA with various neutral pH, amine-based buffers has been analyzed by free solution capillary electrophoresis, using a mixture of a plasmid-sized DNA molecule and a small DNA oligonucleotide as the reporter system. The two DNAs migrate as separate, nearly Gaussian-shaped peaks in 20-80 mM TAE (TAE, Tris-acetate-EDTA; Tris, tris ...
STELLWAGEN +3 more
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Archives of Internal Medicine, 1965
OUR conceptualization and operating knowledge of buffers and buffer mechanisms must, of necessity, have as their basis notions concerning the nature of acids and bases. The concurrent influence of two major theories of acids and bases, those of Arrhenius and Bronsted-Lowry, has resulted in much confusion concerning terminology and definitions in the ...
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OUR conceptualization and operating knowledge of buffers and buffer mechanisms must, of necessity, have as their basis notions concerning the nature of acids and bases. The concurrent influence of two major theories of acids and bases, those of Arrhenius and Bronsted-Lowry, has resulted in much confusion concerning terminology and definitions in the ...
openaire +3 more sources