Results 101 to 110 of about 555,570 (296)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

GROUND WATER FLOW AND WATER BUDGET FOR THARTHAR LAKE

Journal of Engineering and Sustainable Development, 2017
Groundwater inflow to Tharthar lake and leakage from it, in time and space, were evaluated using hydrologic data and simulation model (Processing Modflow Pro) of the groundwater system adjacent to the lake. The temporal parameters include the time unit,
Thair Sharif Khayyun, Mustafa Majeed AbdulAaimma, Ahlam Sajir Mohamad   +2 more
doaj  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Best-value in Korean public building construction

, 2011
Although the low-bid system has played a major role in public building construction sector for a long time, this system has arguably delivered work of low quality, an continued and rising number of claims within the industry.
Park, Junhong
core  

Modification of Pinhole Apparatus for Identification and Classification of Dispersive Clay Soils

Journal of Engineering and Sustainable Development, 2014
In this research, modification of the pinhole apparatus is made as required by the specification of the American Society for Testing and Materials (ASTM D4647 – 93)[3], which works on the basis that distilled water is passed horizontally under the ...
Mohammed Yousif Fattah, Hassan Ali Omran, Thabet Mohammed Abdulatif   +2 more
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Is Construction Industry Still Performing Worse Than Other Industries?

, 2022
Research Questions: Is the construction industry improving performance in Finland? Is construction industry performing worse than other industries? Why is the industry scoring high on customer satisfaction, even if it scores low in many other cross ...
Seppänen, Olli, Elfving, Jan A.
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

THREE-DIMENSIONAL ANALYSIS FOR THE EFFECT OF PILES GEOMETRY AND ARRANGEMENT ON THE DYNAMIC RESPONSE OF PILED RAFT FOUNDATION

Journal of Engineering and Sustainable Development, 2018
In the present study, three-dimensional analysis is presented to investigate the effect of pile dimensions and configuration on the dynamic response of piled raft foundations subjected to vertical vibration.
Mahmood Rashid Al-Qayssi, Saad Faik Al-Wakel, Ihab Ghaleb Abdulwahhab   +2 more
doaj