Results 121 to 130 of about 555,570 (296)

Surveying the extent and use of 4D BIM in the UK

open access: yes, 2016
More than half of construction projects exceed their agreed time schedules. Attempts to remedy this have been monitored over a number of years in the UK using standard industry KPI measurement data.
Greenwood, David, Gledson, Barry
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

PERFORMANCE OF DRIVEN REINFORCED CONCRETE PILES UNDER THE EFFECT OF DYNAMIC LOADING

open access: yesJournal of Engineering and Sustainable Development, 2019
Dynamic analysis for reinforced concrete precast piles with (300x300 mm) in dimension and length (12 m) with different types of loading was carried out. The common precast pile in Iraq was adopted in this study. Finite element analysis by ANSYS software
Mohammed Yousif Fattah   +2 more
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Building construction illustrated / Francis D.K. Ching.

open access: yes, 2014
engineering bookfair2015Includes bibliographical references and index.1 volume (various pagings) :"This new edition of the revered classic remains as relevant as ever, providing the latest information in Francis D.K. Ching's signature style. Its rich and
Ching, Francis D. K., 1943-
core  

GIS APPLICATION TO EVALUATE TRANSPORTATIONS NETWORK IN NASIRIYAH CITY

open access: yesJournal of Engineering and Sustainable Development, 2017
Transportation is an essential element for the development of countries economically, socially, and culturally, where the progress in countries is measured through the progress in transportation systems and urban road networks.
Abdul-Razzak T. Ziboon   +2 more
doaj  

Effect of Steam, Carbonation, and Autoclave Curing on the Mechanical, Durability, and Microstructure Properties of UHPC: A Comprehensive Review

open access: yesAdvances in Civil Engineering
Ultra high-performance concrete (UHPC) is a material that brings revolutionary changes to modern building construction due to its outstanding mechanical, durability, and microstructural properties.
Shuvo Dip Datta, Samir Mazumder
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Construction workers on steel frame of State Office Building

open access: yes, 1931
Photograph of construction workers on the steel frame of the State Office (Ohio Departments of State) building in Columbus, ca. 1931-1932. Groundbreaking for the Ohio State Office Building took place on November 19, 1929.

core  

Home - About - Disclaimer - Privacy